PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6RH4	Human Carbonic Anhydrase II in complex with 4-Nitrobenzenesulfonamide. 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-nitrobenzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-04-18 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.948 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
1ZQP	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF KCL (75 MILLIMOLAR) AND NACL (75 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), POTASSIUM ION, ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-12 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
4JSA	Benzenesulfonamide complexed with hCAII H94D 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, SULFATE ION, ... 著者 Martin, D.P, Hann, Z.S, Cohen, S.M. 登録日 2013-03-22 公開日 2013-06-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site. Inorg.Chem., 52, 2013
9NIK	Structure of E1277A mutant of the acyltransferase domain of NcdE, a multi-domain NRPS protein from nocardichelin biosynthesis 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, NcdE 著者 Fisk, M.B, Gulick, A.M. 登録日 2025-02-26 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. Acs Chem.Biol., 20, 2025
1IH0	Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033 分子名称: 5-[1-(3,4-DIMETHOXY-BENZOYL)-1,2,3,4-TETRAHYDRO-QUINOLIN-6-YL]-6-METHYL-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-ONE, CALCIUM ION, TROPONIN C, ... 著者 Wang, X, Li, M.X, Spyracopoulos, L, Beier, N, Chandra, M, Solaro, R.J, Sykes, B.D. 登録日 2001-04-18 公開日 2001-10-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033. J.Biol.Chem., 276, 2001
9NIJ	Structure of the acyltransferase domain of NcdE, a multi-domain NRPS protein from nocardichelin biosynthesis 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, NcdE 著者 Fisk, M.B, Gulick, A.M. 登録日 2025-02-26 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. Acs Chem.Biol., 20, 2025
9NIM	Structure of a K1305A mutant of the acyltransferase domain of NcdE, a multi-domain NRPS protein from nocardichelin biosynthesis 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NcdE 著者 Fisk, M.B, Gulick, A.M, Barrera Ramirez, J. 登録日 2025-02-26 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Identification and Characterization of the Biosynthesis of the Hybrid NRPS-NIS Siderophore Nocardichelin. Acs Chem.Biol., 20, 2025
6RHJ	Crystal structure of human carbonic anhydrase isozyme II with 4-(4-benzyl-1,4-diazepane-1-carbonyl)benzenesulfonamide 分子名称: 4-[[4-(phenylmethyl)-1,4-diazepan-1-yl]carbonyl]benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Ferraroni, M, Angeli, A, Supuran, C.T. 登録日 2019-04-21 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
3IIA	Crystal structure of apo (91-244) RIa subunit of cAMP-dependent protein kinase 分子名称: GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Sjoberg, T.J, Kim, C, Kornev, A.P, Taylor, S.S. 登録日 2009-07-31 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design. Mol.Cell Proteomics, 10, 2011
9NYY	Nucleic acid bound human SLFN14, State 1 分子名称: MAGNESIUM ION, Protein SLFN14, RNA (5'-R(P*AP*UP*GP*GP*G)-3'), ... 著者 Van Riper, J, Martinez-Claros, A.O, Wang, L, Schneiderman, H, Maheshwari, S, Pillon, M.C. 登録日 2025-03-29 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage Nat Commun, 16, 2025
3IIF	Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form B) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1 著者 Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. 登録日 2009-07-31 公開日 2009-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16, 2009
1ZQR	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF NICL2 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), NICKEL (II) ION, ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-12 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
9FHU	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex hexamannuluronic acid at pH 3.5 分子名称: Alginate lyase family protein, SULFATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FHW	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex tetraguluronic acid at pH 8 分子名称: Alginate lyase family protein, SULFATE ION, alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
6RRI	Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 2,3,5,6-tetrakis(fluoranyl)benzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-18 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.097 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
9FHV	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex pentasaccharide (ManGul)3 at pH 3.5 分子名称: Alginate lyase family protein, SULFATE ION, beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FHX	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex tetramannuronic acid at pH 8 分子名称: Alginate lyase family protein, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
1REK	Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 8 分子名称: 3-[(3-SEC-BUTYL-4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL 4-(2-HYDROXY-5-METHOXYBENZOYL)BENZOATE, PENTANAL, cAMP-dependent protein kinase, ... 著者 Akamine, P, Madhusudan, Brunton, L.L, Ou, H.D, Canaves, J.M, Xuong, N.H, Taylor, S.S. 登録日 2003-11-06 公開日 2004-02-24 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit Biochemistry, 43, 2004
9FHY	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex with an unsaturated mannuronic acid tetramer at pH 3.5 分子名称: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid, Alginate lyase family protein, SULFATE ION 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FHZ	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) wild type in complex unsaturated guluronic acid tetramer at pH 3.5 分子名称: 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, 4-deoxy-alpha-L-erythro-hex-4-enopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid, Alginate lyase family protein, ... 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
6RJH	3D structure of horse spleen apoferritin determined using multifunctional graphene supports for electron cryomicroscopy 分子名称: Ferritin light chain 著者 Naydenova, K, Peet, M.J, Russo, C.J. 登録日 2019-04-26 公開日 2019-06-05 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Multifunctional graphene supports for electron cryomicroscopy. Proc.Natl.Acad.Sci.USA, 116, 2019
9FI0	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant D108N 分子名称: Alginate lyase family protein 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FI2	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant N242A at pH 3.5 分子名称: Alginate lyase family protein 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FI1	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant H297N at pH 3.5 分子名称: Alginate lyase family protein, SULFATE ION 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025
9FI3	Bacteroides ovatus polysaccharide lyase family 38 (BoPL38) mutant Q173N in complex with tetraguluronic acid at pH 3.5 分子名称: Alginate lyase family protein, SULFATE ION 著者 Tandrup, T, Wilkens, C. 登録日 2024-05-28 公開日 2025-07-09 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The Swiss Army Knife of Alginate Metabolism: Mechanistic Analysis of a Mixed-Function Polysaccharide Lyase/Epimerase of the Human Gut Microbiota. J.Am.Chem.Soc., 2025

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