1HQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hqa by Molmil](/molmil-images/mine/1hqa) | ALKALINE PHOSPHATASE (H412Q) | 分子名称: | ALKALINE PHOSPHATASE, ZINC ION | 著者 | Ma, L, Kantrowitz, E.R. | 登録日 | 1995-11-30 | 公開日 | 1996-03-08 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites. Biochemistry, 35, 1996
|
|
5R9D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r9d by Molmil](/molmil-images/mine/5r9d) | |
5R9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5r9t by Molmil](/molmil-images/mine/5r9t) | PanDDA analysis group deposition Form1 MAP kinase p38-alpha -- Fragment N13477a in complex with MAP kinase p38-alpha | 分子名称: | 6-methyl-5-[(4-propan-2-ylphenyl)amino]-2~{H}-1,2,4-triazin-3-one, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | De Nicola, G.F, Nichols, C.E. | 登録日 | 2020-03-04 | 公開日 | 2020-07-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
|
|
4Z3Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z3z by Molmil](/molmil-images/mine/4z3z) | Active site complex BamBC of Benzoyl Coenzyme A reductase in complex with Zinc | 分子名称: | Benzoyl-CoA reductase, putative, IRON/SULFUR CLUSTER, ... | 著者 | Weinert, T, Kung, J.W, Weidenweber, S, Huwiler, S.G, Boll, M, Ermler, U. | 登録日 | 2015-04-01 | 公開日 | 2015-06-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.666 Å) | 主引用文献 | Structural basis of enzymatic benzene ring reduction. Nat.Chem.Biol., 11, 2015
|
|
5RA9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ra9 by Molmil](/molmil-images/mine/5ra9) | |
1UU6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uu6 by Molmil](/molmil-images/mine/1uu6) | X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A IN COMPLEX WITH A SOAKED CELLOPENTAOSE | 分子名称: | ENDO-BETA-1,4-GLUCANASE, TETRAETHYLENE GLYCOL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | 登録日 | 2003-12-15 | 公開日 | 2004-09-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A J.Mol.Biol., 342, 2004
|
|
4NU5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nu5 by Molmil](/molmil-images/mine/4nu5) | Crystal Structure of PTDH R301A | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Phosphonate dehydrogenase | 著者 | Nair, S.K, Chekan, J.R. | 登録日 | 2013-12-03 | 公開日 | 2014-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Chemical rescue and inhibition studies to determine the role of arg301 in phosphite dehydrogenase. Plos One, 9, 2014
|
|
5KN9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kn9 by Molmil](/molmil-images/mine/5kn9) | MutY N-terminal domain in complex with DNA containing an intrahelical oxoG:A base-pair | 分子名称: | Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*CP*AP*GP*GP*AP*T)-3'), ... | 著者 | Wang, L, Chakravarthy, S, Verdine, G.L. | 登録日 | 2016-06-27 | 公開日 | 2017-02-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase. J. Biol. Chem., 292, 2017
|
|
1UXT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uxt by Molmil](/molmil-images/mine/1uxt) | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Lorentzen, E, Hensel, R, Pohl, E. | 登録日 | 2004-03-01 | 公開日 | 2004-08-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
|
|
4ND1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nd1 by Molmil](/molmil-images/mine/4nd1) | |
1V3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v3i by Molmil](/molmil-images/mine/1v3i) | The roles of Glu186 and Glu380 in the catalytic reaction of soybean beta-amylase | 分子名称: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | 登録日 | 2003-11-02 | 公開日 | 2004-06-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Roles of Glu186 and Glu380 in the Catalytic Reaction of Soybean beta-Amylase. J.Mol.Biol., 339, 2004
|
|
1V3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v3u by Molmil](/molmil-images/mine/1v3u) | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase in apo form | 分子名称: | CHLORIDE ION, leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase | 著者 | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-11-05 | 公開日 | 2004-07-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop J.Biol.Chem., 279, 2004
|
|
3PCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pcf by Molmil](/molmil-images/mine/3pcf) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 3-FLURO-4-HYDROXYBENZOATE | 分子名称: | 3-FLUORO-4-HYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, FE (III) ION, ... | 著者 | Orville, A.M, Elango, N, Lipscomb, J.D, Ohlendorf, D.H. | 登録日 | 1997-06-27 | 公開日 | 1998-01-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry, 36, 1997
|
|
3PCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pcc by Molmil](/molmil-images/mine/3pcc) | STRUCTURE OF PROTOCATECHUATE 3,4-DIOXYGENASE COMPLEXED WITH 4-HYDROXYBENZOATE | 分子名称: | BETA-MERCAPTOETHANOL, FE (III) ION, P-HYDROXYBENZOIC ACID, ... | 著者 | Elango, N, Orville, A.M, Lipscomb, J.D, Ohlendorf, D.H. | 登録日 | 1997-04-29 | 公開日 | 1998-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structures of competitive inhibitor complexes of protocatechuate 3,4-dioxygenase: multiple exogenous ligand binding orientations within the active site. Biochemistry, 36, 1997
|
|
1HXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hxk by Molmil](/molmil-images/mine/1hxk) | GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R. | 登録日 | 2001-01-16 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells. EMBO J., 20, 2001
|
|
4NGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ngv by Molmil](/molmil-images/mine/4ngv) | Previously de-ionized HEW lysozyme batch crystallized in 0.5 M YbCl3 | 分子名称: | CHLORIDE ION, Lysozyme C, YTTERBIUM (III) ION | 著者 | Benas, P, Legrand, L, Ries-Kautt, M. | 登録日 | 2013-11-03 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Weak protein-cationic co-ion interactions addressed by X-ray crystallography and mass spectrometry. Acta Crystallogr.,Sect.D, 70, 2014
|
|
4ZDZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zdz by Molmil](/molmil-images/mine/4zdz) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with fluconazole | 分子名称: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R.K, Tyndall, J.D.A, Monk, B.C. | 登録日 | 2015-04-20 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
|
|
1UIE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uie by Molmil](/molmil-images/mine/1uie) | |
1HP1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hp1 by Molmil](/molmil-images/mine/1hp1) | 5'-NUCLEOTIDASE (OPEN FORM) COMPLEX WITH ATP | 分子名称: | 5'-NUCLEOTIDASE, ADENOSINE-5'-TRIPHOSPHATE, CARBONATE ION, ... | 著者 | Knoefel, T, Straeter, N. | 登録日 | 2000-12-12 | 公開日 | 2002-03-20 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of hydrolysis of phosphate esters by the dimetal center of 5'-nucleotidase based on crystal structures. J.Mol.Biol., 309, 2001
|
|
3PBL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pbl by Molmil](/molmil-images/mine/3pbl) | Structure of the human dopamine D3 receptor in complex with eticlopride | 分子名称: | 3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide, D(3) dopamine receptor, Lysozyme chimera, ... | 著者 | Chien, E.Y.T, Liu, W, Han, G.W, Katritch, V, Zhao, Q, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | 登録日 | 2010-10-20 | 公開日 | 2010-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist. Science, 330, 2010
|
|
1UIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uic by Molmil](/molmil-images/mine/1uic) | |
4NHS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nhs by Molmil](/molmil-images/mine/4nhs) | X-ray structure of the complex between hen egg white lysozyme and pentachlorocarbonyliridate(III) (9 days) | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION, ... | 著者 | Petruk, A.A, Bikiel, D.E, Vergara, A, Merlino, A. | 登録日 | 2013-11-05 | 公開日 | 2014-09-17 | 最終更新日 | 2015-06-24 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Interaction between proteins and Ir based CO releasing molecules: mechanism of adduct formation and CO release. Inorg.Chem., 53, 2014
|
|
1URB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1urb by Molmil](/molmil-images/mine/1urb) | ALKALINE PHOSPHATASE (N51MG) | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Tibbitts, T.T, Murphy, J.E, Kantrowitz, E.R. | 登録日 | 1996-02-03 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase. J.Mol.Biol., 257, 1996
|
|
4NHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nhx by Molmil](/molmil-images/mine/4nhx) | Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with N-oxalylglycine (NOG) | 分子名称: | 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Horita, S, McDonough, M.A, Schofield, C.J. | 登録日 | 2013-11-05 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | 主引用文献 | Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
|
|
3PBG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pbg by Molmil](/molmil-images/mine/3pbg) | 6-PHOSPHO-BETA-GALACTOSIDASE FORM-C | 分子名称: | 6-PHOSPHO-BETA-D-GALACTOSIDASE, SULFATE ION | 著者 | Wiesmann, C, Schulz, G.E. | 登録日 | 1997-02-21 | 公開日 | 1997-07-23 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures and mechanism of 6-phospho-beta-galactosidase from Lactococcus lactis. J.Mol.Biol., 269, 1997
|
|