5HVX
 
 | | Full length Wild-Type Open-form Sodium Channel NavMs | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, ... | | 著者 | Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. | | 登録日 | 2016-01-28 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The complete structure of an activated open sodium channel.
Nat Commun, 8, 2017
|
|
5H8H
 | | Structure of the human GluN1/GluN2A LBD in complex with GNE3419 | | 分子名称: | 7-[[ethyl(phenyl)amino]methyl]-2-methyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one, ACETATE ION, CALCIUM ION, ... | | 著者 | Wallweber, H.J.A, Lupardus, P.J. | | 登録日 | 2015-12-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
Neuron, 89, 2016
|
|
3L8N
 | | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A | | 分子名称: | Brefeldin A-inhibited guanine nucleotide-exchange protein 2 | | 著者 | Seetharaman, J, Su, M, Forouhar, F, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-12-31 | | 公開日 | 2010-04-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Crystal Structure of a domain of Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BrefeldinA-inhibited GEP 2) from Homo sapiens (Human). Northeast Structural Genomics Consortium target id HR5562A
To be Published
|
|
5HW3
 | |
3LP5
 | |
5H92
 | | Crystal structure of the complex between maize Sulfite Reductase and ferredoxin in the form-3 crystal | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, chloroplastic, ... | | 著者 | Kurisu, G, Nakayama, M, Hase, T. | | 登録日 | 2015-12-25 | | 公開日 | 2016-04-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural and mutational studies of an electron transfer complex of maize sulfite reductase and ferredoxin.
J.Biochem., 160, 2016
|
|
5HWF
 | |
3L8U
 | |
3L9D
 | |
5H9L
 | | Crystal Structure of LTBP1 in complex with cleaved Leukotriene C4 | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, GLUTATHIONE, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-28 | | 公開日 | 2016-05-11 | | 最終更新日 | 2016-07-27 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
|
|
3LPB
 | | Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor | | 分子名称: | N-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide, Tyrosine-protein kinase JAK2 | | 著者 | Tavares, G.A, Pissot-Soldermann, C, Gerspacher, M, Furet, P, Kroemer, M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-04-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
|
|
5HWM
 | | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | | 分子名称: | 2-OXOADIPIC ACID, FORMIC ACID, Probable 5-dehydro-4-deoxyglucarate dehydratase | | 著者 | Taberman, H, Parkkinen, T, Hakulinen, N, Rouvinen, J. | | 登録日 | 2016-01-29 | | 公開日 | 2016-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Structure and function of a decarboxylating Agrobacterium tumefaciens keto-deoxy-d-galactarate dehydratase.
Biochemistry, 53, 2014
|
|
5H9Q
 | | Crystal Structure of Human Galectin-7 in Complex with TD139 | | 分子名称: | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, Galectin-7 | | 著者 | Hsieh, T.J, Lin, H.Y, Lin, C.H. | | 登録日 | 2015-12-29 | | 公開日 | 2016-06-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.931 Å) | | 主引用文献 | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
|
|
3L9N
 | | crystal structure of PKAB3 (pka triple mutant V123A, L173M, Q181K) with compound 27 | | 分子名称: | (2S)-N~1~-[5-(1H-indazol-5-yl)-1,3,4-thiadiazol-2-yl]-3-(4-methylphenyl)propane-1,2-diamine, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | | 著者 | Huang, X. | | 登録日 | 2010-01-05 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Azole-based inhibitors of AKT/PKB for the treatment of cancer.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
5HA0
 | | Crystal structure of the LTBP1 leukotriene d4 complex | | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-29 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
|
|
3LQH
 | |
5HXG
 | | STM1697-FlhD complex | | 分子名称: | Flagellar transcriptional regulator FlhD, Uncharacterized protein STM1697 | | 著者 | Li, B, Yuan, Z, Qin, L, Gu, L. | | 登録日 | 2016-01-30 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | | 主引用文献 | Crystal structure of STM1697-FlhD complex
To Be Published
|
|
6UIU
 | | Artificial Iron Proteins: Modelling the Active Sites in Non-Heme Dioxygenases | | 分子名称: | N-(2-{bis[(pyridin-2-yl)methyl]amino}ethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide, Streptavidin | | 著者 | Miller, K.R, Paretsky, J.D, Follmer, A.H, Heinisch, T, Mittra, K, Gul, S, Kim, I.-S, Fuller, F.D, Batyuk, A, Sutherlin, K.D, Brewster, A.S, Bhowmick, A, Sauter, N.K, Kern, J, Yano, J, Green, M.T, Ward, T.R, Borovik, A.S. | | 登録日 | 2019-10-01 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Artificial Iron Proteins: Modeling the Active Sites in Non-Heme Dioxygenases.
Inorg.Chem., 59, 2020
|
|
5HA8
 | |
5HY4
 | | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | | 分子名称: | Ring-opening amidohydrolase | | 著者 | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | | 登録日 | 2016-02-01 | | 公開日 | 2017-02-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
|
|
3LQN
 | | Crystal Structure of CBS Domain-containing Protein of Unknown Function from Bacillus anthracis str. Ames Ancestor | | 分子名称: | CBS domain protein, FORMIC ACID, GLYCEROL, ... | | 著者 | Kim, Y, Mulligan, R, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-02-09 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of CBS Domain-containing Protein of Unknown Function from Bacillus anthracis str. Ames Ancestor
To be Published
|
|
3LR1
 | | The crystal structure of the tungstate ABC transporter from Geobacter sulfurreducens | | 分子名称: | GLYCEROL, TUNGSTEN ION, Tungstate ABC transporter, ... | | 著者 | Zhang, R, Volkart, L, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-02-10 | | 公開日 | 2010-03-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of the tungstate ABC transporter from Geobacter sulfurreducens
To be Published
|
|
5HAE
 | | Crystal structure of LTBP1 LTC4 complex collected on an in-house source | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, GLUTATHIONE, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-30 | | 公開日 | 2016-05-11 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
|
|
3LAI
 | | Structural insights into the molecular mechanism of H-NOX activation | | 分子名称: | IMIDAZOLE, Methyl-accepting chemotaxis protein, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Olea Jr, C, Herzik Jr, M.A, Kuriyan, J, Marletta, M.A. | | 登録日 | 2010-01-06 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.144 Å) | | 主引用文献 | Structural insights into the molecular mechanism of H-NOX activation.
Protein Sci., 19, 2010
|
|
5HZ0
 | |
