5HA0

Crystal structure of the LTBP1 leukotriene d4 complex

Summary for 5HA0

Related5H9L 5H9N 5HAE
DescriptorLipocalin AI-4, (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid (3 entities in total)
Functional Keywordslipocalin, leukotriene, rhodnius, salivary, transport protein
Biological sourceRhodnius prolixus (Triatomid bug)
Total number of polymer chains1
Total molecular weight17401.37
Authors
Andersen, J.F. (deposition date: 2015-12-29, release date: 2016-05-11, Last modification date: 2016-07-27)
Primary citation
Jablonka, W.,Pham, V.,Nardone, G.,Gittis, A.,Silva-Cardoso, L.,Atella, G.C.,Ribeiro, J.M.,Andersen, J.F.
Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11:1934-1944, 2016
PubMed: 27124118 (PDB entries with the same primary citation)
DOI: 10.1021/acschembio.6b00032
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.441 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.188100.8%3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution