PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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3GYB	Crystal structure of a LacI-family transcriptional regulatory protein from Corynebacterium glutamicum 分子名称: MAGNESIUM ION, Transcriptional regulators (LACI-FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN) 著者 Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-03 公開日 2009-04-14 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a LacI-family transcriptional regulatory protein from Corynebacterium glutamicum To be Published
6TZ6	Crystal Structure of Candida Albicans Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus) 分子名称: 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... 著者 Fox III, D, Lukacs, C.M. 登録日 2019-08-10 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nat Commun, 10, 2019
6UMY	Crystal structure of photoactive yellow protein (PYP); F96(4-IF) construct 分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein 著者 Lin, C.-Y, Romei, M.G, Boxer, S.G. 登録日 2019-10-10 公開日 2020-07-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (0.923 Å) 主引用文献 Structural and spectroscopic characterization of photoactive yellow protein and photoswitchable fluorescent protein constructs containing heavy atoms. J Photochem Photobiol A Chem, 401, 2020
8DKD	Sliding clamp from M. thermoresistibile 分子名称: Beta sliding clamp 著者 Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. 登録日 2022-07-05 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Interaction of sliding clamp with mycobacterial polymerases To Be Published
6M9L	Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping - compound 10 分子名称: 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, Mitogen-activated protein kinase 14 著者 Lane, W, Okada, K. 登録日 2018-08-23 公開日 2019-04-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1. Chemmedchem, 14, 2019
3LFF	Human p38 MAP Kinase in Complex with RL166 分子名称: (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1H-pyrazol-1-yl}phenyl)acetic acid, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
3LFE	Human p38 MAP Kinase in Complex with RL116 分子名称: 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(pyridin-4-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
6U5J	CryoEM Structure of Pyocin R2 - postcontracted - collar 分子名称: Collar PA0615, Sheath PA0622 著者 Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. 登録日 2019-08-27 公開日 2020-04-15 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
6P7V	Structure of the K. lactis CBF3 core 分子名称: Cep3, Ctf13, Skp1 著者 Lee, P.D, Wei, H, Tan, D, Harrison, S.C. 登録日 2019-06-06 公開日 2019-09-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of the Centromere Binding Factor 3 Complex from Kluyveromyces lactis. J.Mol.Biol., 431, 2019
3LFA	Human p38 MAP Kinase in Complex with Dasatinib 分子名称: Mitogen-activated protein kinase 14, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
3LFB	Human p38 MAP Kinase in Complex with RL98 分子名称: 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
6UN2	Crystal structure of photoactive yellow protein (PYP); C69U construct (selenocysteine incorporation) 分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein 著者 Lin, C.-Y, Romei, M.G, Boxer, S.G. 登録日 2019-10-10 公開日 2020-07-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Structural and spectroscopic characterization of photoactive yellow protein and photoswitchable fluorescent protein constructs containing heavy atoms. J Photochem Photobiol A Chem, 401, 2020
6UND	Pseudomonas fluorescens isocyanide hydratase thioimidate intermediate at 298 K XFEL data 分子名称: Isonitrile hydratase InhA, N-(4-nitrophenyl)methanimine 著者 Dasgupta, M, van den Bedem, H, Wilson, M.A. 登録日 2019-10-11 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis. Proc.Natl.Acad.Sci.USA, 116, 2019
6UN0	Crystal structure of photoactive yellow protein (PYP); F96(4-IF) construct with 3-Br-p-coumaric acid chromophore 分子名称: (2E)-3-(3-bromo-4-hydroxyphenyl)prop-2-enoic acid, Photoactive yellow protein 著者 Lin, C.-Y, Romei, M.G, Boxer, S.G. 登録日 2019-10-10 公開日 2020-07-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 Structural and spectroscopic characterization of photoactive yellow protein and photoswitchable fluorescent protein constructs containing heavy atoms. J Photochem Photobiol A Chem, 401, 2020
6RVD	Revised cryo-EM structure of the human 2:1 Ptch1-Shh complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 El Omari, K, Rudolf, A.F, Kowatsch, C, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. 登録日 2019-05-31 公開日 2019-10-02 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
3LFD	Human p38 MAP Kinase in Complex with RL113 分子名称: 1-{4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. 登録日 2010-01-16 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha To be Published
6UKA	Crystal structure of RHOG and ELMO complex 分子名称: Engulfment and cell motility protein 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Jo, C.H, Killoran, R.C, Smith, M.J. 登録日 2019-10-04 公開日 2020-08-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state. Nat Commun, 11, 2020
6UNF	Pseudomonas fluorescens isocyanide hydratase post-catalysis at 298 K XFEL data 分子名称: Isonitrile hydratase InhA 著者 Dasgupta, M, van den Bedem, H, Wilson, M.A. 登録日 2019-10-11 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis. Proc.Natl.Acad.Sci.USA, 116, 2019
5XWR	Crystal Structure of RBBP4-peptide complex 分子名称: Histone-binding protein RBBP4, MET-SER-ARG-ARG-LYS-GLN-ALA-LYS-PRO-GLN-HIS-ILE 著者 Jobichen, C, Lui, B.H, Daniel, G.T, Sivaraman, J. 登録日 2017-06-30 公開日 2018-07-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6TWR	Structure of a constitutively active CAT-PRD1 mutant of the antiterminator LicT protein. 分子名称: Beta-glucoside bgl operon antiterminator BglG family 著者 Demene, H, Declerck, N, Yinshan, Y. 登録日 2020-01-13 公開日 2021-04-14 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Resolving the activation mechanism of the D99N antiterminator LicT protein. J.Struct.Biol., 213, 2021
8UJW	Crystal structure of the KETc7 antigen from Taenia solium 分子名称: GRAM domain-containing protein 著者 Sotelo-Mundo, R.R, Gomez-Yanes, A.C, Lopez-Zavala, A.A, Ochoa-Leyva, A. 登録日 2023-10-11 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structure of the KETc7 antigen from Taenia solium To Be Published
6UP3	Crystal structure of the murine DHX36 helicase in complex with ANP 分子名称: Dhx36 protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Chuenchor, W, Jiang, J, Xiao, T.S. 登録日 2019-10-16 公開日 2020-10-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.691 Å) 主引用文献 Crystal structure of the murine DHX36 helicase in complex with ANP To be published
5XXQ	Crystal structure of RBBP4: ZNF827 and its function in telomere 分子名称: Histone-binding protein RBBP4, Zinc finger protein 827 著者 Sun, A, Shi, Y. 登録日 2017-07-04 公開日 2018-08-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of RBBP4: ZNF827 and its function in telomere To Be Published
5Y1U	Crystal structure of RBBP4 bound to AEBP2 RRK motif 分子名称: Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2 著者 Sun, A, Li, F, Wu, J, Shi, Y. 登録日 2017-07-21 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.141 Å) 主引用文献 Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4 Protein Cell, 2017
6M95	Structure-based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridine-2-one based p38 MAP Kinase Inhibitors by scaffold hopping: compound 1 分子名称: (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone, Mitogen-activated protein kinase 14 著者 Lane, W, Okada, K. 登録日 2018-08-22 公開日 2019-04-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1. Chemmedchem, 14, 2019

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