5UE3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ue3 by Molmil](/molmil-images/mine/5ue3) | proMMP-9desFnII | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Matrix metalloproteinase-9, ... | 著者 | Alexander, R.S, Spurlino, J, Milligan, C. | 登録日 | 2016-12-29 | 公開日 | 2017-09-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation. J. Biol. Chem., 292, 2017
|
|
2NPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2npc by Molmil](/molmil-images/mine/2npc) | |
6ASD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6asd by Molmil](/molmil-images/mine/6asd) | Zinc finger region of human TET1 in complex with CpG DNA | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase TET1, UNKNOWN ATOM OR ION, ... | 著者 | Liu, K, Xu, C, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-08-24 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 26, 2018
|
|
4YD5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yd5 by Molmil](/molmil-images/mine/4yd5) | |
2NPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2npk by Molmil](/molmil-images/mine/2npk) | |
4YBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ybf by Molmil](/molmil-images/mine/4ybf) | Aspartic Proteinase Sapp2 Secreted from Candida Parapsilosis at 1.25 A Resolution | 分子名称: | Candidapepsin-2, DI(HYDROXYETHYL)ETHER | 著者 | Dostal, J, Hruskova-Heidingsfeldova, O, Rezacova, P, Brynda, J, Mareckova, L, Pichova, I. | 登録日 | 2015-02-18 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis. Acta Crystallogr.,Sect.D, 71, 2015
|
|
6B3W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b3w by Molmil](/molmil-images/mine/6b3w) | Structure of Hs/AcPRC2 in complex with 5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one | 分子名称: | 5,8-dichloro-7-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one, Enhancer of zeste 2 polycomb repressive complex 2 subunit,Enhancer of zeste 2 polycomb repressive complex 2 subunit, Polycomb protein EED, ... | 著者 | Gajiwala, K.S, Brooun, A, Liu, W, Deng, Y, Stewart, A.E. | 登録日 | 2017-09-25 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497). J. Med. Chem., 61, 2018
|
|
2NDN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ndn by Molmil](/molmil-images/mine/2ndn) | NMR solution structure of PawS Derived Peptide 20 (PDP-20) | 分子名称: | PawS1a Derived Peptide 20 | 著者 | Franke, B, Jayasena, A.S, Fisher, M.F, Swedberg, J.E, Taylor, N.L, Mylne, J.S, Rosengren, K. | 登録日 | 2016-07-26 | 公開日 | 2016-08-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Diverse cyclic seed peptides in the Mexican zinnia (Zinnia haageana). Biopolymers, 106, 2016
|
|
2NPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2npj by Molmil](/molmil-images/mine/2npj) | |
4YU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yu1 by Molmil](/molmil-images/mine/4yu1) | |
4Y3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y3h by Molmil](/molmil-images/mine/4y3h) | |
6B65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b65 by Molmil](/molmil-images/mine/6b65) | IMPase (AF2372) R92Q/K164E | 分子名称: | DI(HYDROXYETHYL)ETHER, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ISOPROPYL ALCOHOL, ... | 著者 | Goldstein, R.I, Roberts, M. | 登録日 | 2017-10-01 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
|
|
5UC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uc5 by Molmil](/molmil-images/mine/5uc5) | |
4Y51
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y51 by Molmil](/molmil-images/mine/4y51) | |
4Y5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y5b by Molmil](/molmil-images/mine/4y5b) | |
6AO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ao6 by Molmil](/molmil-images/mine/6ao6) | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) | 分子名称: | COPPER (II) ION, GLYCEROL, NICKEL (II) ION, ... | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | 登録日 | 2017-08-15 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase. Commun Biol, 1, 2018
|
|
6B8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b8a by Molmil](/molmil-images/mine/6b8a) | Crystal structure of MvfR ligand binding domain in complex with M64 | 分子名称: | 2-[(5-nitro-1H-benzimidazol-2-yl)sulfanyl]-N-(4-phenoxyphenyl)acetamide, COBALT HEXAMMINE(III), DNA-binding transcriptional regulator | 著者 | Kitao, T, Steinbacher, S, Maskos, K, Blaesse, M, Rahme, L.G. | 登録日 | 2017-10-05 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Molecular Insights into Function and Competitive Inhibition ofPseudomonas aeruginosaMultiple Virulence Factor Regulator. MBio, 9, 2018
|
|
4Y5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y5p by Molmil](/molmil-images/mine/4y5p) | |
5UEK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uek by Molmil](/molmil-images/mine/5uek) | |
6B8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6b8y by Molmil](/molmil-images/mine/6b8y) | |
5UE6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ue6 by Molmil](/molmil-images/mine/5ue6) | Structure of nitrite reductase AniA from Neisseria gonorrhoeae, space group I4122 | 分子名称: | COPPER (II) ION, Nitrite reductase, SODIUM ION | 著者 | Hamza, A, Williamson, Z.A, Reed, R.W, Sikora, A.E, Korotkov, K.V. | 登録日 | 2016-12-29 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA. Antimicrob. Agents Chemother., 61, 2017
|
|
2NBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nbv by Molmil](/molmil-images/mine/2nbv) | |
4YL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yl9 by Molmil](/molmil-images/mine/4yl9) | Crystal Structure of wild-type of hsp14.1 from Sulfolobus solfatataricus P2 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Heat shock protein Hsp20 | 著者 | Liu, L, Chen, J.Y, Yun, C.H. | 登録日 | 2015-03-05 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function Structure, 23, 2015
|
|
6AUY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6auy by Molmil](/molmil-images/mine/6auy) | Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-Methyl-6-(3-(3-(methylamino)propyl)phenethyl)pyridin-2-amine | 分子名称: | 4-methyl-6-(2-{3-[3-(methylamino)propyl]phenyl}ethyl)pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... | 著者 | Li, H, Poulos, T.L. | 登録日 | 2017-09-01 | 公開日 | 2018-07-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker. J. Med. Chem., 60, 2017
|
|
4Y8V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y8v by Molmil](/molmil-images/mine/4y8v) | |