2H7C
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![BU of 2h7c by Molmil](/molmil-images/mine/2h7c) | Crystal structure of human carboxylesterase in complex with Coenzyme A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COENZYME A, ... | 著者 | Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R. | 登録日 | 2006-06-02 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 J.Mol.Biol., 363, 2006
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6GIW
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![BU of 6giw by Molmil](/molmil-images/mine/6giw) | Water-soluble Chlorophyll Protein (WSCP) from Lepidium virginicum (Mutation L91P) with Chlorophyll-a | 分子名称: | CHLOROPHYLL A, Water-soluble chlorophyll protein | 著者 | Palm, D.M, Agostini, A, Averesch, V, Girr, P, Werwie, M, Takahashi, S, Satoh, H, Jaenicke, E, Paulsen, H. | 登録日 | 2018-05-15 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Chlorophyll a/b binding-specificity in water-soluble chlorophyll protein. Nat Plants, 4, 2018
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2B1U
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![BU of 2b1u by Molmil](/molmil-images/mine/2b1u) | Solution structure of Calmodulin-like Skin Protein C terminal domain | 分子名称: | Calmodulin-like protein 5 | 著者 | Babini, E, Bertini, I, Capozzi, F, Chirivino, E, Luchinat, C, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-09-16 | 公開日 | 2006-05-30 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A Structural and Dynamic Characterization of the EF-Hand Protein CLSP. Structure, 14, 2006
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6GKK
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![BU of 6gkk by Molmil](/molmil-images/mine/6gkk) | Translation initiation factor 4E in complex with beta-phosphorothioate trinucleotide mRNA 5' cap diastereomer 1 (m7GppSpApG D1) | 分子名称: | Eukaryotic translation initiation factor 4E, GLYCEROL, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate | 著者 | Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M. | 登録日 | 2018-05-21 | 公開日 | 2019-06-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.858 Å) | 主引用文献 | Translation initiation factor 4E in complex with beta-phosphorothioate trinucleotide mRNA 5' cap diastereomer 1 (m7GppSpApG D1) To Be Published
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2UXE
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![BU of 2uxe by Molmil](/molmil-images/mine/2uxe) | The structure of Vaccinia virus N1 | 分子名称: | HYPOTHETICAL PROTEIN | 著者 | Cooray, S, Bahar, M.W, Abrescia, N.G.A, McVey, C.E, Bartlett, N.W, Chen, R.A.-J, Stuart, D.I, Grimes, J.M, Smith, G.L. | 登録日 | 2007-03-28 | 公開日 | 2007-05-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Functional and Structural Studies of the Vaccinia Virus Virulence Factor N1 Reveal a Bcl-2-Like Anti- Apoptotic Protein J.Gen.Virol., 88, 2007
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3B1U
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![BU of 3b1u by Molmil](/molmil-images/mine/3b1u) | Crystal structure of human peptidylarginine deiminase 4 in complex with o-F-amidine | 分子名称: | 2-{[(2S)-1-amino-5-{[(1Z)-2-fluoroethanimidoyl]amino}-1-oxopentan-2-yl]carbamoyl}benzoic acid, CALCIUM ION, Protein-arginine deiminase type-4, ... | 著者 | Causey, C.P, Jones, J.E, Slack, J.L, Kamei, D, Jones Jr, L.E, Subramanian, V, Knuckley, B, Ebrahimi, P, Chumanevich, A.A, Luo, Y, Hashimoto, H, Shimizu, T, Sato, M, Hofseth, L.J, Thompson, P.R. | 登録日 | 2011-07-13 | 公開日 | 2011-10-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Development of N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine Amide (o-F-amidine) and N-alpha-(2-Carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine Amide (o-Cl-amidine) As Second Generation Protein Arginine Deiminase (PAD) Inhibitors J.Med.Chem., 54, 2011
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3IZ0
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![BU of 3iz0 by Molmil](/molmil-images/mine/3iz0) | Human Ndc80 Bonsai Decorated Microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Alushin, G.M, Ramey, V.H, Pasqualato, S, Ball, D.A, Grigorieff, N, Musacchio, A, Nogales, E. | 登録日 | 2010-08-09 | 公開日 | 2010-10-13 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | 主引用文献 | The Ndc80 kinetochore complex forms oligomeric arrays along microtubules. Nature, 467, 2010
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6GO9
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![BU of 6go9 by Molmil](/molmil-images/mine/6go9) | Structure of GFPmut2 crystallized at pH 6 and transferred to pH 7 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Green fluorescent protein | 著者 | Lolli, G, Raboni, S, Pasqualetto, E, Campanini, B, Mozzarelli, A, Bettati, S, Battistutta, R. | 登録日 | 2018-06-01 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | 主引用文献 | Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography. J.Phys.Chem.B, 122, 2018
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4IJ1
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![BU of 4ij1 by Molmil](/molmil-images/mine/4ij1) | Bianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (AnPRT; trpD) in absence of substrates. | 分子名称: | 2,2'-iminodibenzoic acid, Anthranilate phosphoribosyltransferase, GLYCEROL, ... | 著者 | Evans, G.L, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-12-20 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis. Chembiochem, 15, 2014
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1E14
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![BU of 1e14 by Molmil](/molmil-images/mine/1e14) | PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M197 REPLACED WITH ARG (CHAIN M, FM197R) AND GLY M203 REPLACED WITH ASP (CHAIN M, GM203D) | 分子名称: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | 著者 | Fyfe, P.K, Ridge, J.P, McAuley, K.E, Cogdell, R.J, Isaacs, N.W, Jones, M.R. | 登録日 | 2000-04-18 | 公開日 | 2000-06-02 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Consequences of the Replacement of Glycine M203 with Aspartic Acid in the Reaction Center from Rhodobacter Sphaeroides. Biochemistry, 39, 2000
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3UQR
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![BU of 3uqr by Molmil](/molmil-images/mine/3uqr) | Crystal structure of BACE1 with its inhibitor | 分子名称: | Beta-secretase 1, METHYL (2S)-1-[(2R,5S,8S,12S,13S)-2,13-DIBENZYL-12-HYDROXY-3,5-DIMETHYL-15-(3-[METHYL(METHYLSULFONYL)AMINO]-5-{[(1R)-1-PHENYLETHYL]CARBAMOYL}PHENYL)-8-(2-METHYLPROPYL)-4,7,10,15-TETRAOXO-3,6,9,14-TETRAAZAPENTADECAN-1-OYL]PYRROLIDINE-2-CARBOXYLATE | 著者 | Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. | 登録日 | 2011-11-21 | 公開日 | 2012-11-21 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.056 Å) | 主引用文献 | Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012
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2AJ1
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![BU of 2aj1 by Molmil](/molmil-images/mine/2aj1) | Solution structure of apoCadA | 分子名称: | Probable cadmium-transporting ATPase | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Su, X.-C, Miras, R, Bal, N, Mintz, E, Catty, P, Shokes, J.E, Scott, R.A. | 登録日 | 2005-08-01 | 公開日 | 2006-05-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for metal binding specificity: the N-terminal cadmium binding domain of the P1-type ATPase CadA J.Mol.Biol., 356, 2006
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4IIQ
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![BU of 4iiq by Molmil](/molmil-images/mine/4iiq) | |
6GU4
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![BU of 6gu4 by Molmil](/molmil-images/mine/6gu4) | CDK1/CyclinB/Cks2 in complex with CGP74514A | 分子名称: | Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 2, G2/mitotic-specific cyclin-B1, ... | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | 登録日 | 2018-06-19 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
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6GUH
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![BU of 6guh by Molmil](/molmil-images/mine/6guh) | CDK2 in complex with AZD5438 | 分子名称: | 1,2-ETHANEDIOL, 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine, Cyclin-dependent kinase 2 | 著者 | Wood, D.J, Korolchuk, S, Tatum, N.J, Wang, L.Z, Endicott, J.A, Noble, M.E.M, Martin, M.P. | 登録日 | 2018-06-19 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition. Cell Chem Biol, 26, 2019
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1JYD
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![BU of 1jyd by Molmil](/molmil-images/mine/1jyd) | Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution | 分子名称: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | 著者 | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | 登録日 | 2001-09-12 | 公開日 | 2003-07-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Role of conserved residues in structure and stability: Tryptophans of human serum
retinol-binding protein, a model for the lipocalin superfamily Protein Sci., 10, 2001
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6GUO
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![BU of 6guo by Molmil](/molmil-images/mine/6guo) | Siderophore hydrolase EstA from Aspergillus nidulans | 分子名称: | CHLORIDE ION, GLYCEROL, Putative siderophore-degrading esterase (Eurofung), ... | 著者 | Ecker, F, Haas, H, Groll, M, Huber, E.M. | 登録日 | 2018-06-19 | 公開日 | 2018-08-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases. Angew. Chem. Int. Ed. Engl., 57, 2018
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5A21
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![BU of 5a21 by Molmil](/molmil-images/mine/5a21) | Structure of bacteriophage SPP1 head-to-tail interface without DNA and tape measure protein | 分子名称: | 15 PROTEIN, HEAD COMPLETION PROTEIN GP16, MAJOR TAIL PROTEIN 17.1, ... | 著者 | Chaban, Y, Lurz, R, Brasiles, S, Cornilleau, C, Karreman, M, Zinn-Justin, S, Tavares, P, Orlova, E.V. | 登録日 | 2015-05-06 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structural Rearrangements in the Phage Head-to-Tail Interface During Assembly and Infection. Proc.Natl.Acad.Sci.USA, 112, 2015
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3DYF
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![BU of 3dyf by Molmil](/molmil-images/mine/3dyf) | T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461 and Isopentyl Diphosphate | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, ACETATE ION, ... | 著者 | Cao, R, Gao, Y, Robinson, H, Goddard, A, Oldfield, E. | 登録日 | 2008-07-27 | 公開日 | 2009-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. J.Am.Chem.Soc., 131, 2009
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6H3H
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![BU of 6h3h by Molmil](/molmil-images/mine/6h3h) | Fab fragment of antibody against fullerene C60 | 分子名称: | Anti-fullerene antibody Fab fragment Heavy chain, Anti-fullerene antibody Fab fragment Light chain, GLYCEROL, ... | 著者 | Osipov, E.M, Tikhonova, T.V. | 登録日 | 2018-07-18 | 公開日 | 2019-05-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of the Anti-C60 Fullerene Antibody Fab Fragment: Structural Determinants of Fullerene Binding. Acta Naturae, 11, 2019
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6H3S
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![BU of 6h3s by Molmil](/molmil-images/mine/6h3s) | Schmallenberg Virus Glycoprotein Gc Head/Stalk Domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Envelopment polyprotein, ... | 著者 | Hellert, J, Aebischer, A, Wernike, K, Haouz, A, Brocchi, E, Reiche, S, Guardado-Calvo, P, Beer, M, Rey, F.A. | 登録日 | 2018-07-19 | 公開日 | 2019-02-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.023 Å) | 主引用文献 | Orthobunyavirus spike architecture and recognition by neutralizing antibodies. Nat Commun, 10, 2019
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6H3X
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![BU of 6h3x by Molmil](/molmil-images/mine/6h3x) | Oropouche Virus Glycoprotein Gc Head Domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Polyprotein, ... | 著者 | Hellert, J, Aebischer, A, Wernike, K, Haouz, A, Brocchi, E, Reiche, S, Guardado-Calvo, P, Beer, M, Rey, F.A. | 登録日 | 2018-07-19 | 公開日 | 2019-02-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.092 Å) | 主引用文献 | Orthobunyavirus spike architecture and recognition by neutralizing antibodies. Nat Commun, 10, 2019
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3UN8
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![BU of 3un8 by Molmil](/molmil-images/mine/3un8) | Yeast 20S proteasome in complex with PR-957 (epoxide) | 分子名称: | 2-(acetylamino)-4,5-anhydro-1,2-dideoxy-4-methyl-1-phenyl-D-xylitol, Proteasome component C1, Proteasome component C11, ... | 著者 | Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. | 登録日 | 2011-11-15 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148, 2012
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3IYP
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![BU of 3iyp by Molmil](/molmil-images/mine/3iyp) | The Interaction of Decay-accelerating Factor with Echovirus 7 | 分子名称: | Capsid protein, Complement decay-accelerating factor, LAURIC ACID, ... | 著者 | Plevka, P, Hafenstein, S, Zhang, Y, Harris, K.G, Cifuente, J.O, Bowman, V.D, Chipman, P.R, Lin, F, Medof, D.E, Bator, C.M, Rossmann, M.G. | 登録日 | 2010-04-07 | 公開日 | 2010-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Interaction of decay-accelerating factor with echovirus 7. J.Virol., 84, 2010
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6H4G
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![BU of 6h4g by Molmil](/molmil-images/mine/6h4g) | Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, INOSINE, Protein kinase A regulatory subunit | 著者 | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | 登録日 | 2018-07-21 | 公開日 | 2019-08-14 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.143517 Å) | 主引用文献 | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
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