PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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3U85	Crystal structure of human menin in complex with MLL1 分子名称: Histone-lysine N-methyltransferase 2A, Menin 著者 Huang, J, Wan, B, Lei, M. 登録日 2011-10-15 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
4LNF	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q 分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ... 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.949 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
2Q1Z	Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR 分子名称: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ... 著者 Campbell, E.A, Darst, S.A. 登録日 2007-05-25 公開日 2007-09-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria. Mol.Cell, 27, 2007
1MJA	Crystal structure of yeast Esa1 histone acetyltransferase domain complexed with acetyl coenzyme A 分子名称: COENZYME A, Esa1 protein 著者 Yan, Y, Harper, S, Speicher, D, Marmorstein, R. 登録日 2002-08-27 公開日 2002-10-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
7XHE	Crystal structure of CBP bromodomain liganded with CCS151 分子名称: (6S)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]-1-(3-fluoranyl-4-methoxy-phenyl)piperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein 著者 Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. 登録日 2022-04-08 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
7XH6	Crystal structure of CBP bromodomain liganded with CCS1477 分子名称: (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, DIMETHYL SULFOXIDE, ... 著者 Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. 登録日 2022-04-07 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
7XI0	Crystal structure of CBP bromodomain liganded with CCS150 分子名称: (6S)-1-(3-chloranyl-4-methoxy-phenyl)-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(3R)-1-methylsulfonylpyrrolidin-3-yl]benzimidazol-2-yl]piperidin-2-one, CREB-binding protein, GLYCEROL 著者 Xu, H, Xiang, Q, Wang, C, Zhang, C, Luo, G, Wu, X, Zhang, Y, Xu, Y. 登録日 2022-04-11 公開日 2022-07-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain Biochem.Biophys.Res.Commun., 623, 2022
6P5J	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
1MME	THE CRYSTAL STRUCTURE OF AN ALL-RNA HAMMERHEAD RIBOZYME: A PROPOSED MECHANISM FOR RNA CATALYTIC CLEAVAGE 分子名称: RNA HAMMERHEAD RIBOZYME 著者 Scott, W.G, Finch, J.T, Klug, A. 登録日 1995-12-09 公開日 1996-02-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell(Cambridge,Mass.), 81, 1995
6P5I	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-02-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
7XC3	Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) 分子名称: Papain-like protease nsp3 著者 Li, J, Gao, J. 登録日 2022-03-22 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen. J.Med.Chem., 65, 2022
3H5T	Crystal structure of a transcriptional regulator, Lacl family protein from Corynebacterium glutamicum 分子名称: Transcriptional regulator, LacI family 著者 Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-22 公開日 2009-05-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Crystal structure of a transcriptional regulator, Lacl family protein from Corynebacterium glutamicum To be Published
7XC4	Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin 分子名称: 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid, Papain-like protease nsp3 著者 Li, J, Liu, Y, Gao, J, Ruan, K. 登録日 2022-03-22 公開日 2022-11-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen. J.Med.Chem., 65, 2022
1MJ9	Crystal structure of yeast Esa1(C304S) mutant complexed with Coenzyme A 分子名称: COENZYME A, ESA1 PROTEIN, SODIUM ION 著者 Yan, Y, Harper, S, Speicher, D, Marmorstein, R. 登録日 2002-08-27 公開日 2002-10-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
7X8B	Crystal structure of ENL T1 mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-11 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7X8G	Crystal structure of ENL T1(H116P) mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-12 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7XCL	Crystal structure of trimethylamine methyltransferase MttB from Methanosarcina barkeri at 2.5 A resolution 分子名称: GLYCEROL, SODIUM ION, Trimethylamine methyltransferase 著者 Li, J, Chan, M.K. 登録日 2022-03-24 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex. Commun Biol, 6, 2023
7X8F	Crystal structure of ENL T4 mutant YEATS domain in complex with histone H3 acetylation at K27 分子名称: CHLORIDE ION, H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y, Peng, B, Li, H. 登録日 2022-03-12 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7XCM	Crystal structure of sulfite MttB structure at 3.2 A resolution 分子名称: 3-METHYL-5-SULFO-PYRROLIDINE-2-CARBOXYLIC ACID, GLYCEROL, SODIUM ION, ... 著者 Li, J, Chan, M.K. 登録日 2022-03-24 公開日 2023-01-18 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex. Commun Biol, 6, 2023
7X88	Crystal structure of ENL YEATS domain T2 mutant in complex with histone H3 acetylation at K27 分子名称: CITRIC ACID, Histone H3K27ac(24-27) peptide, Protein ENL 著者 Li, Y.Y, Li, H.T. 登録日 2022-03-11 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. Mol.Cell, 82, 2022
7XCN	Crystal structure of the MttB-MttC complex at 2.7 A resolution 分子名称: 5-HYDROXYBENZIMIDAZOLYLCOBAMIDE, GLYCEROL, Trimethylamine methyltransferase, ... 著者 Li, J, Chan, M.K. 登録日 2022-03-24 公開日 2023-01-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex. Commun Biol, 6, 2023
1M4M	Mouse Survivin 分子名称: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 5, ZINC ION 著者 Muchmore, S.W, Chen, J, Jakob, C, Zakula, D, Matayoshi, E.D, Wu, W, Zhang, H, Li, F, Ng, S.C, Altieri, D.C. 登録日 2002-07-03 公開日 2002-09-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 CRYSTAL STRUCTURE AND MUTAGENIC ANALYSIS OF THE INHIBITOR-OF-APOPTOSIS PROTEIN SURVIVIN MOL.CELL, 6, 2000
1MKJ	Human Kinesin Motor Domain With Docked Neck Linker 分子名称: ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ... 著者 Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R. 登録日 2002-08-29 公開日 2002-10-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy. Nat.Struct.Biol., 9, 2002
7WVB	Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state 分子名称: Fructose-1,6-bisphosphatase 1 著者 Chen, Y, Zhang, J, Li, C, Cao, Y. 登録日 2022-02-10 公開日 2023-02-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state To Be Published
8AGA	Structure of p-hydroxy benzoic acid ligand bound HosA transcriptional regulator from enteropathogenic Escherichia coli O127:H6 (strain E2348/69) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, P-HYDROXYBENZOIC ACID, ... 著者 Goswami, A, Kannika, B.R, Madan Kumar, S. 登録日 2022-07-19 公開日 2023-08-02 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Horizontally acquired HosA transcription factor bound with 4-hydroxy-benzoic acid exhibits unique tug-of-water dynamics Biorxiv, 2024

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