6MZM
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![BU of 6mzm by Molmil](/molmil-images/mine/6mzm) | Human TFIID bound to promoter DNA and TFIIA | 分子名称: | SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | 登録日 | 2018-11-05 | 公開日 | 2018-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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6O2T
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![BU of 6o2t by Molmil](/molmil-images/mine/6o2t) | Acetylated Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | 登録日 | 2019-02-24 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6NMI
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![BU of 6nmi by Molmil](/molmil-images/mine/6nmi) | Cryo-EM structure of the human TFIIH core complex | 分子名称: | CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ... | 著者 | Greber, B.J, Toso, D, Fang, J, Nogales, E. | 登録日 | 2019-01-10 | 公開日 | 2019-03-13 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The complete structure of the human TFIIH core complex. Elife, 8, 2019
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6O2S
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![BU of 6o2s by Molmil](/molmil-images/mine/6o2s) | Deacetylated Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | 登録日 | 2019-02-24 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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3PP0
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![BU of 3pp0 by Molmil](/molmil-images/mine/3pp0) | Crystal Structure of the Kinase domain of Human HER2 (erbB2). | 分子名称: | 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol, Receptor tyrosine-protein kinase erbB-2 | 著者 | Skene, R.J, Aertgeerts, K, Sogabe, S. | 登録日 | 2010-11-23 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein. J.Biol.Chem., 286, 2011
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3L29
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![BU of 3l29 by Molmil](/molmil-images/mine/3l29) | Crystal Structure of Zaire Ebola VP35 interferon inhibitory domain K319A/R322A mutant | 分子名称: | CHLORIDE ION, Polymerase cofactor VP35 | 著者 | Leung, D.W, Ramanan, P, Borek, D.M, Amarasinghe, G.K. | 登録日 | 2009-12-14 | 公開日 | 2010-02-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mutations abrogating VP35 interaction with double-stranded RNA render ebola virus avirulent in guinea pigs. J.Virol., 84, 2010
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4XA7
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![BU of 4xa7 by Molmil](/molmil-images/mine/4xa7) | Soluble part of holo NqrC from V. harveyi | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit C | 著者 | Borshchevskiy, V, Round, E, Bertsova, Y, Polovinkin, V, Gushchin, I, Mishin, A, Kovalev, K, Kachalova, G, Popov, A, Bogachev, A, Gordeliy, V. | 登録日 | 2014-12-12 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structural and Functional Investigation of Flavin Binding Center of the NqrC Subunit of Sodium-Translocating NADH:Quinone Oxidoreductase from Vibrio harveyi. Plos One, 10, 2015
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2MBL
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![BU of 2mbl by Molmil](/molmil-images/mine/2mbl) | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 | 分子名称: | Top7 Fold Protein Top7m13 | 著者 | Liu, G, Zanghellini, A.L, Chan, K, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-08-02 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 To be Published
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6HYG
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![BU of 6hyg by Molmil](/molmil-images/mine/6hyg) | Heteromeric tandem IgG4/IgG1 Fc | 分子名称: | IgHG1 and IgHG4 hybrid, ZINC ION | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-21 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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2MBM
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![BU of 2mbm by Molmil](/molmil-images/mine/2mbm) | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 | 分子名称: | Top7 Fold Protein Top7m13 | 著者 | Liu, G, Zanghellini, A.L, Chan, K, Xiao, R, Janjua, H, Kogan, S, Maglaqui, M, Ciccosanti, C, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-08-02 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 To be Published
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6I6I
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![BU of 6i6i by Molmil](/molmil-images/mine/6i6i) | Circular permutant of ribosomal protein S6, adding 6aa to C terminal of P68-69, L75A mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6, SULFATE ION | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2018-11-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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4XCR
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![BU of 4xcr by Molmil](/molmil-images/mine/4xcr) | Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, mutant I35A | 分子名称: | Superoxide dismutase [Cu-Zn] | 著者 | Wang, H, Logan, D.T, Danielsson, J, Mu, X, Binolfi, A, Theillet, F, Bekei, B, Lang, L, Wennerstrom, H, Selenko, P, Oliveberg, M. | 登録日 | 2014-12-18 | 公開日 | 2016-01-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.602 Å) | 主引用文献 | Thermodynamics of protein destabilization in live cells. Proc. Natl. Acad. Sci. U.S.A., 112, 2015
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6RSW
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![BU of 6rsw by Molmil](/molmil-images/mine/6rsw) | HFD domain of mouse CAP1 bound to the pointed end of G-actin | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | 著者 | Kotila, T, Kogan, K, Lappalainen, P. | 登録日 | 2019-05-22 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat Commun, 10, 2019
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6I6E
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6ICH
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![BU of 6ich by Molmil](/molmil-images/mine/6ich) | Grb2 SH2 domain in domain swapped dimer form | 分子名称: | Growth factor receptor-bound protein 2 | 著者 | Hosoe, Y, Numoto, N, Inaba, S, Ogawa, S, Morii, H, Abe, R, Ito, N, Oda, M. | 登録日 | 2018-09-06 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and functional properties of Grb2 SH2 dimer in CD28 binding. Biophys Physicobio., 16, 2019
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4OEC
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![BU of 4oec by Molmil](/molmil-images/mine/4oec) | Crystal structure of glycerophosphodiester phosphodiesterase from Thermococcus kodakarensis KOD1 | 分子名称: | Glycerophosphoryl diester phosphodiesterase, MAGNESIUM ION | 著者 | Atsuta, Y, You, D.J, Takano, K, Koga, Y, Kanaya, S. | 登録日 | 2014-01-13 | 公開日 | 2015-01-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of glycerophosphodiester phosphodiesterase from Thermococcus kodakarensis KOD1 To be Published
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4Y04
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![BU of 4y04 by Molmil](/molmil-images/mine/4y04) | Crystal structure of dipeptidyl peptidase 11 (DPP11) from Porphyromonas gingivalis (Space) | 分子名称: | GLYCEROL, POTASSIUM ION, Peptidase S46 | 著者 | Sakamoto, Y, Suzuki, Y, Iizuka, I, Tateoka, C, Roppongi, S, Fujimoto, M, Inaka, K, Tanaka, H, Yamada, M, Ohta, K, Nonaka, T, Ogasawara, W, Tanaka, N. | 登録日 | 2015-02-05 | 公開日 | 2015-07-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity. Sci Rep, 5, 2015
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6I69
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2MVF
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![BU of 2mvf by Molmil](/molmil-images/mine/2mvf) | Structural insight into an essential assembly factor network on the pre-ribosome | 分子名称: | Uncharacterized protein | 著者 | Lee, W, Bassler, J, Paternoga, H, Holdermann, I, Thomas, M, Granneman, S, Barrio-Garcia, C, Nyarko, A, Stier, G, Clark, S.A, Schraivogel, D, Kallas, M, Beckmann, R, Tollervey, D, Barbar, E, Sinning, I, Hurt, E. | 登録日 | 2014-10-02 | 公開日 | 2014-12-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
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6I6O
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![BU of 6i6o by Molmil](/molmil-images/mine/6i6o) | Circular permutant of ribosomal protein S6, swap helix 2, L75A mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6 | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2018-11-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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6I6Y
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6IAU
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![BU of 6iau by Molmil](/molmil-images/mine/6iau) | Amine Dehydrogenase from Cystobacter fuscus in complex with NADP+ and cyclohexylamine | 分子名称: | Amine Dehydrogenase, CYCLOHEXYLAMMONIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Beloti, L, Mayol, O, Turkenburg, J.P, Vaxelaire-Vergne, C, Grogan, G. | 登録日 | 2018-11-27 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | A family of native amine dehydrogenases for the asymmetric reductive amination of ketones Nat Catal, 2019
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6IC5
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![BU of 6ic5 by Molmil](/molmil-images/mine/6ic5) | Human cathepsin-C in complex with dipeptidyl cyclopropyl nitrile inhibitor 2 | 分子名称: | (2~{S})-2-azanyl-~{N}-[(1~{R},2~{R})-1-(iminomethyl)-2-[4-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]cyclopropyl]-3-thiophen-2-yl-propanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Hakansson, M, Logan, D.T, Korkmaz, B, Lesner, A, Wysocka, M, Gieldon, A, Gauthier, F, Jenne, D, Lauritzen, C, Pedersen, J. | 登録日 | 2018-12-02 | 公開日 | 2019-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochem. Pharmacol., 164, 2019
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6RT8
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![BU of 6rt8 by Molmil](/molmil-images/mine/6rt8) | Structure of catharanthine synthase - an alpha-beta hydrolase from Catharanthus roseus with a cleaviminium intermediate bound | 分子名称: | 18-carboxymethoxy-cleaviminium, Catharanthine synthase, HEXAETHYLENE GLYCOL | 著者 | Caputi, L, Franke, J, Bussey, K, Farrow, S.C, Curcino Vieira, I.J, Stevenson, C.E.M, Lawson, D.M, O'Connor, S.E. | 登録日 | 2019-05-22 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids. Nat.Chem.Biol., 16, 2020
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6I6U
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![BU of 6i6u by Molmil](/molmil-images/mine/6i6u) | Circular permutant of ribosomal protein S6, adding 9aa to N terminal of P81-82, L75A mutant | 分子名称: | 30S ribosomal protein S6,30S ribosomal protein S6 | 著者 | Wang, H, Logan, D.T, Oliveberg, M. | 登録日 | 2018-11-15 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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