PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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8V5Z	UIC-1 mutant - UIC-1-L6M 分子名称: ACETONITRILE, UIC-1-L6M 著者 Heinz-Kunert, S.L. 登録日 2023-12-01 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (0.84 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8V5Y	Crystal structure of Tyr p 36.0101 in complex with a poly(L-proline) peptide 分子名称: Profilin, SULFATE ION, poly(L-proline) peptide 著者 O'Malley, A, Chruszcz, M. 登録日 2023-12-01 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.059 Å) 主引用文献 Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity. Biol.Chem., 405, 2024
8V5X	UIC-1 mutant - UIC-1-L6A 分子名称: ACETONITRILE, UIC-1-L6A 著者 Heinz-Kunert, S.L. 登録日 2023-12-01 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8V5W	UIC-1 mutant UIC-1-B5T 分子名称: UIC-1-B5T 著者 Heinz-Kunert, S.L. 登録日 2023-12-01 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8V5R	Active conformation of DNA polymerase gamma bound to DNA 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, ... 著者 Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. 登録日 2023-11-30 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
8V5O	Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-11-30 公開日 2023-12-20 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (8.99 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8V5N	Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-11-30 公開日 2023-12-20 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (8.56 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8V5M	Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-11-30 公開日 2023-12-20 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (9.22 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8V5K	Structure of the Human Respirovirus 3 Fusion Protein Bound to Camelid Nanobodies 4C03 and 4C06 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid Nanobody 4C03, Camelid Nanobody 4C06, ... 著者 Johnson, N.V, Ramamohan, A.R, McLellan, J.S. 登録日 2023-11-30 公開日 2024-05-22 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for potent neutralization of human respirovirus type 3 by protective single-domain camelid antibodies. Nat Commun, 15, 2024
8V5G	Crystal Structure of Acetyl-CoA synthetase from Cryptococcus neoformans H99 in complex with an ethylsulfamide AMP inhibitor 分子名称: 5'-deoxy-5'-(ethylsulfamamido)adenosine, Acetyl-coenzyme A synthetase, CHLORIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-11-30 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Acetyl-CoA synthetase from Cryptococcus neoformans H99 in complex with an ethylsulfamide AMP inhibitor To be published
8V5D	Human mitochondrial DNA polymerase catalytic subunit, PolG, in an APO conformation 分子名称: DNA polymerase subunit gamma-1 著者 Riccio, A.A, Brannon, A.J, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. 登録日 2023-11-30 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
8V5A	Prefusion-stabilized Respirovirus type 3 Fusion protein 分子名称: Camelid nanobody 4C06, Fusion glycoprotein F0 著者 Johnson, N.V, McLellan, J.S. 登録日 2023-11-30 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein. Nat Commun, 15, 2024
8V59	UIC-1 mutant - UIC-1-B5I 分子名称: METHANOL, UIC-1-B5I 著者 Heinz-Kunert, S.L. 登録日 2023-11-30 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8V56	UIC-1 mutant - UIC-1-B5W 分子名称: UIC-1-B5W 著者 Heinz-Kunert, S.L. 登録日 2023-11-30 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Pore Restructuring of Peptide Frameworks by Mutations at Distal Packing Residues. Biomacromolecules, 25, 2024
8V55	Human mitochondrial DNA polymerase gamma bound to a replication fork in an open conformation 分子名称: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... 著者 Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, M.J, Copeland, W.C. 登録日 2023-11-30 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
8V54	Engaged conformation of the human mitochondrial DNA polymerase gamma bound to DNA 分子名称: DNA (25-MER), DNA (44-MER), DNA polymerase subunit gamma-1, ... 著者 Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. 登録日 2023-11-30 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
8V52	Crystal structure of 2A10 Fab bound to Human TGF-beta3 分子名称: 2A10 Fab Heavy Chain, 2A10 Fab Light chain, Transforming growth factor beta-3 著者 Yin, J, Lupardus, P.J. 登録日 2023-11-30 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Isoform-selective TGF-beta 3 inhibition for systemic sclerosis. Med, 5, 2024
8V4Y	Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ... 著者 Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y. 登録日 2023-11-29 公開日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking. Nat Commun, 15, 2024
8V4X	Structure of MALT1 in complex with an allosteric inhibitor 分子名称: Inhibitor peptide, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, N-{7-[(1S)-1-methoxyethyl]-2-methyl[1,3]thiazolo[5,4-b]pyridin-6-yl}-N'-[6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea 著者 Judge, R.A, Pappano, W.N. 登録日 2023-11-29 公開日 2024-05-01 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.486 Å) 主引用文献 Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma. Mol.Cancer Ther., 23, 2024
8V4U	Structure of SARS-CoV-2 main protease in complex with a covalent inhibitor 分子名称: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide 著者 Greasley, S.E, Ferre, R.A, Liu, W. 登録日 2023-11-29 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.819 Å) 主引用文献 A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19. J.Med.Chem., 2024
8V4R	Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans 分子名称: ACETIC ACID, ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-11-29 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP and CoA from Candida albicans To be published
8V4Q	Myxococcus xanthus EncA 3xHis pore mutant with tetrahedral symmetry 分子名称: Type 1 encapsulin shell protein EncA 著者 Szyszka, T.N, Andreas, M.P, Lie, F, Miller, L.M, Adamson, L.S.R, Fatehi, F, Twarock, R, Draper, B.E, Jarrold, M.F, Giessen, T.W, Lau, Y.H. 登録日 2023-11-29 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages. Proc.Natl.Acad.Sci.USA, 121, 2024
8V4P	Crystal structure of Acetyl-CoA synthetase 2 in complex with Adenosine-5'-allylphosphate from Candida albicans 分子名称: 5'-O-{(S)-hydroxy[(prop-2-en-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-11-29 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Acetyl-CoA synthetase 2 in complex with Adenosine-5'-allylphosphate from Candida albicans To be published
8V4O	Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans 分子名称: ADENOSINE MONOPHOSPHATE, Acetyl-coenzyme A synthetase 2, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-11-29 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of Acetyl-CoA synthetase 2 in complex with AMP from Candida albicans To be published
8V4N	Myxococcus xanthus EncA 3xHis pore mutant with T=1 icosahedral symmetry 分子名称: Type 1 encapsulin shell protein EncA 著者 Szyszka, T.N, Andreas, M.P, Lie, F, Miller, L.M, Adamson, L.S.R, Fatehi, F, Twarock, R, Draper, B.E, Jarrold, M.F, Giessen, T.W, Lau, Y.H. 登録日 2023-11-29 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.43 Å) 主引用文献 Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages. Proc.Natl.Acad.Sci.USA, 121, 2024

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