5IEX
 
 | | Crystal structure of (R,S)-S-{4-[(5-Bromo-4-{[(2R,3R)-2-hydroxy-1-methylpropyl]oxy}- pyrimidin-2-yl)amino]phenyl}-S-cyclopropylsulfoximide bound to CDK2 | | 分子名称: | (2R,3R)-3-[(5-bromo-2-{[4-(S-cyclopropylsulfonimidoyl)phenyl]amino}pyrimidin-4-yl)oxy]butan-2-ol, Cyclin-dependent kinase 2 | | 著者 | Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M. | | 登録日 | 2016-02-25 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016
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5IOJ
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5I1C
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FAB HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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1VCB
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1LLO
 | | HEVAMINE A (A PLANT ENDOCHITINASE/LYSOZYME) COMPLEXED WITH ALLOSAMIDIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, Hevamine-A | | 著者 | Terwisscha Van Scheltinga, A.C, Armand, S, Kalk, K.H, Isogai, A, Henrissat, B, Dijkstra, B.W. | | 登録日 | 1995-11-08 | | 公開日 | 1996-03-08 | | 最終更新日 | 2022-06-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis.
Biochemistry, 34, 1995
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5I09
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5I1A
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-11 | | 分子名称: | ACETATE ION, CNTO388 HEAVY CHAIN, CNTO388 LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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1V73
 | | Crystal Structure of Cold-Active Protein-Tyrosine Phosphatase of a Psychrophile Shewanella SP. | | 分子名称: | ACETIC ACID, CALCIUM ION, psychrophilic phosphatase I | | 著者 | Tsuruta, H, Mikami, B, Aizono, Y. | | 登録日 | 2003-12-09 | | 公開日 | 2005-03-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal Structure of Cold-Active Protein-Tyrosine Phosphatase from a Psychrophile, Shewanella sp
J.Biochem.(Tokyo), 137, 2005
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5I7H
 | | Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 6 [3-(3-(4-Bromophenyl)ureido)benzoic acid] | | 分子名称: | 3-{[(4-bromophenyl)carbamoyl]amino}benzoic acid, CHLORIDE ION, O-phosphoserine sulfhydrylase, ... | | 著者 | Schnell, R, Maric, S, Schneider, G. | | 登録日 | 2016-02-17 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
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1LTH
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5IAA
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1V4V
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1KCD
 | | Endopolygalacturonase I from Stereum purpureum complexed with two galacturonate at 1.15 A resolution. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ENDOPOLYGALACTURONASE, ... | | 著者 | Shimizu, T, Nakatsu, T, Miyairi, K, Okuno, T, Kato, H. | | 登録日 | 2001-11-08 | | 公開日 | 2002-06-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution.
Biochemistry, 41, 2002
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1KCC
 | | Endopolygalacturonase I from Stereum purpureum complexed with a galacturonate at 1.00 A resolution. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ENDOPOLYGALACTURONASE, ... | | 著者 | Shimizu, T, Nakatsu, T, Miyairi, K, Okuno, T, Kato, H. | | 登録日 | 2001-11-08 | | 公開日 | 2002-06-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Active-site architecture of endopolygalacturonase I from Stereum purpureum revealed by crystal structures in native and ligand-bound forms at atomic resolution.
Biochemistry, 41, 2002
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1KRQ
 | | CRYSTAL STRUCTURE ANALYSIS OF CAMPYLOBACTER JEJUNI FERRITIN | | 分子名称: | ferritin | | 著者 | Hortolan, L, Saintout, N, Granier, G, Langlois d'Estaintot, B, Manigand, C, Mizunoe, Y, Wai, S.N, Gallois, B, Precigoux, G. | | 登録日 | 2002-01-10 | | 公開日 | 2002-02-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | STRUCTURE OF CAMPYLOBACTER JEJUNI FERRITIN AT 2.7 A RESOLUTION
To be Published
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5KUT
 | | hMiro2 C-terminal GTPase domain, GDP-bound | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 2 | | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | 登録日 | 2016-07-13 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.693 Å) | | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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5KOW
 | | Structure of rifampicin monooxygenase | | 分子名称: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pentachlorophenol 4-monooxygenase | | 著者 | Tanner, J.J, Liu, L.-K. | | 登録日 | 2016-07-01 | | 公開日 | 2016-09-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Structure of the Antibiotic Deactivating, N-hydroxylating Rifampicin Monooxygenase.
J.Biol.Chem., 291, 2016
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5KIR
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5KKC
 | | l-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD | | 分子名称: | L-lactate dehydrogenase A chain, SULFATE ION, [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Meneely, K.M, Moran, G.R, Lamb, A.L. | | 登録日 | 2016-06-21 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.859 Å) | | 主引用文献 | Ligand binding phenomena that pertain to the metabolic function of renalase.
Arch.Biochem.Biophys., 612, 2016
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1ULQ
 | | Crystal structure of tt0182 from Thermus thermophilus HB8 | | 分子名称: | putative acetyl-CoA acetyltransferase | | 著者 | Ago, H, Hamada, K, Ida, K, Kanda, H, Sugahara, M, Yamamoto, M, Kuroishi, C, Kuramitsu, S, Yokoyama, S, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-16 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of tt0182 from Thermus thermophilus HB8
To be Published
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5KNC
 | | Crystal structure of the 3 ADP-bound V1 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Suzuki, K, Mizutani, K, Maruyama, S, Shimono, K, Imai, F.L, Muneyuki, E, Kakinuma, Y, Ishizuka-Katsura, Y, Shirouzu, M, Yokoyama, S, Yamato, I, Murata, T. | | 登録日 | 2016-06-28 | | 公開日 | 2016-11-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.015 Å) | | 主引用文献 | Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor
Nat Commun, 7, 2016
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5KP0
 | | Recognition and targeting mechanisms by chaperones in flagella assembly and operation | | 分子名称: | Flagellar protein FliT,Flagellum-specific ATP synthase | | 著者 | Khanra, N.K, Rossi, P, Economou, A, Kalodimos, C.G. | | 登録日 | 2016-07-01 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Recognition and targeting mechanisms by chaperones in flagellum assembly and operation.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5KKN
 | | Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 | | 分子名称: | 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 | | 著者 | Wang, R, Paul, D, Tong, L. | | 登録日 | 2016-06-22 | | 公開日 | 2016-07-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1KI3
 | | CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH PENCICLOVIR | | 分子名称: | 9-(4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL)GUANINE, SULFATE ION, THYMIDINE KINASE | | 著者 | Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Jarvest, R.L, Summers, W.C, Sanderson, M.R. | | 登録日 | 1998-05-15 | | 公開日 | 1999-05-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
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1UWX
 | | P1.2 serosubtype antigen derived from N. meningitidis PorA in complex with Fab fragment | | 分子名称: | ANTIBODY, CLASS 1 OUTER MEMBRANE PROTEIN VARIABLE REGION 2, PROTEIN G-PRIME | | 著者 | Tzitzilonis, C, Prince, S.M, Collins, R.F, Maiden, M.C.J, Feavers, I.M, Derrick, J.P. | | 登録日 | 2004-02-12 | | 公開日 | 2005-06-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Variation and Immune Recognition of the P1.2 Subtype Meningococcal Antigen.
Proteins: Struct., Funct., Bioinf., 62, 2005
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