7KE5
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![BU of 7ke5 by Molmil](/molmil-images/mine/7ke5) | Heavy chain ferritin with N-terminal EBNA1 epitope | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Epstein-Barr nuclear antigen 1,Ferritin heavy chain, FE (III) ION | 著者 | Pederick, J.P, Bruning, J.B. | 登録日 | 2020-10-10 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Immunogenicity study of engineered ferritins with C- and N-terminus insertion of Epstein-Barr nuclear antigen 1 epitope. Vaccine, 39, 2021
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6BZF
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6BW6
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![BU of 6bw6 by Molmil](/molmil-images/mine/6bw6) | Human GPT (DPAGT1) H129 variant in complex with tunicamycin | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase | 著者 | Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y. | 登録日 | 2017-12-14 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation. Nat. Struct. Mol. Biol., 25, 2018
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7JVS
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7RN6
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7KE3
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![BU of 7ke3 by Molmil](/molmil-images/mine/7ke3) | Heavy chain ferritin with C-terminal EBNA1 epitope | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, Ferritin heavy chain,Epstein-Barr nuclear antigen 1 | 著者 | Pederick, J.L, Bruning, J.B. | 登録日 | 2020-10-10 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Immunogenicity study of engineered ferritins with C- and N-terminus insertion of Epstein-Barr nuclear antigen 1 epitope. Vaccine, 39, 2021
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6OYH
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![BU of 6oyh by Molmil](/molmil-images/mine/6oyh) | Crystal structure of MraY bound to carbacaprazamycin | 分子名称: | (5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine, MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase | 著者 | Mashalidis, E.H, Lee, S.Y. | 登録日 | 2019-05-14 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun, 10, 2019
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | 分子名称: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | 著者 | Montemayor, E.J, Brow, D.A, Butcher, S.E. | 登録日 | 2016-09-24 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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6Z1A
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![BU of 6z1a by Molmil](/molmil-images/mine/6z1a) | Ternary complex of Staphylococcus aureus DNA gyrase with AMK12 and DNA | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Kolaric, A, Germe, T, Hrast, M, Stevenson, C.E.M, Lawson, D.M, Burton, N, Voros, J, Maxwell, A, Minovski, N, Anderluh, M. | 登録日 | 2020-05-13 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds. Nat Commun, 12, 2021
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6C08
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6OMX
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7JW5
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![BU of 7jw5 by Molmil](/molmil-images/mine/7jw5) | Crystal structure of WT-CYP199A4 in complex with 4-phenylbenzoic acid | 分子名称: | CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | 登録日 | 2020-08-24 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.526 Å) | 主引用文献 | Different Geometric Requirements for Cytochrome P450-Catalyzed Aliphatic Versus Aromatic Hydroxylation Results in Chemoselective Oxidation Acs Catalysis, 12, 2022
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6GQ4
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![BU of 6gq4 by Molmil](/molmil-images/mine/6gq4) | Neisseria gonorrhoeae Adhesin Complex Protein | 分子名称: | Adhesin, SODIUM ION | 著者 | Orr, C.M, Tews, I. | 登録日 | 2018-06-07 | 公開日 | 2018-09-19 | 最終更新日 | 2018-10-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure of the RecombinantNeisseria gonorrhoeaeAdhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci. mSphere, 3, 2018
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5G41
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![BU of 5g41 by Molmil](/molmil-images/mine/5g41) | Crystal structure of adenylate kinase ancestor 4 with Zn, Mg and Ap5A bound | 分子名称: | ADENYLATE KINSE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... | 著者 | Nguyen, V, Kutter, S, English, J, Kern, D. | 登録日 | 2016-05-03 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Evolutionary drivers of thermoadaptation in enzyme catalysis. Science, 355, 2017
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5G52
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![BU of 5g52 by Molmil](/molmil-images/mine/5g52) | Crystallographic structure of full particle of Deformed Wing Virus | 分子名称: | URIDINE-5'-MONOPHOSPHATE, VP1, VP2, ... | 著者 | Skubnik, K, Novacek, J, Fuzik, T, Pridal, A, Paxton, R, Plevka, P. | 登録日 | 2016-05-18 | 公開日 | 2017-03-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.802 Å) | 主引用文献 | Structure of deformed wing virus, a major honey bee pathogen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7JT8
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![BU of 7jt8 by Molmil](/molmil-images/mine/7jt8) | Apo structure of a pseudomurein peptide ligase type E from Methanothermus fervidus | 分子名称: | MAGNESIUM ION, Mur ligase middle domain protein, SULFATE ION | 著者 | Carbone, V, Schofield, L.R, Sutherland-Smith, A.J, Ronimus, R.S, Subedi, B.P. | 登録日 | 2020-08-17 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases. Microbiology (Reading, Engl.), 168, 2022
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5G65
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6C18
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![BU of 6c18 by Molmil](/molmil-images/mine/6c18) | FGFR1 kinase complex with inhibitor SN37115 | 分子名称: | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{(3S)-1-[(2E)-4-(dimethylamino)but-2-enoyl]pyrrolidin-3-yl}-7-[(propan-2-yl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Fibroblast growth factor receptor 1, SULFATE ION | 著者 | Yosaatmadja, Y, Smaill, J.B, Squire, C.J. | 登録日 | 2018-01-04 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Understanding the structural requirements for covalent inhibition of FGFR1-3 To Be Published
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7JXQ
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![BU of 7jxq by Molmil](/molmil-images/mine/7jxq) | EGFR kinase (T790M/V948R) in complex with allosteric inhibitor JBJ-09-063 | 分子名称: | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... | 著者 | Beyett, T.S, Eck, M.J. | 登録日 | 2020-08-27 | 公開日 | 2021-09-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer. Nat Cancer, 3, 2022
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5G4E
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![BU of 5g4e by Molmil](/molmil-images/mine/5g4e) | S. enterica HisA mutant D10G, Dup13-15, Q24L, G102A, V106L | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, ACETIC ACID, GLYCEROL, ... | 著者 | Soderholm, A, Guo, X, Newton, M, Nasvall, J, Duarte, F, Andersson, D, Patrick, W, Selmer, M. | 登録日 | 2016-05-12 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5G6P
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6OF9
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6K0P
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![BU of 6k0p by Molmil](/molmil-images/mine/6k0p) | Catalytic domain of GH87 alpha-1,3-glucanase D1045A in complex with nigerose | 分子名称: | ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ... | 著者 | Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T. | 登録日 | 2019-05-07 | 公開日 | 2019-12-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.424 Å) | 主引用文献 | Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11. Febs J., 287, 2020
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6GQF
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![BU of 6gqf by Molmil](/molmil-images/mine/6gqf) | The structure of mouse AsterA (GramD1a) with 25-hydroxy cholesterol | 分子名称: | 25-HYDROXYCHOLESTEROL, GLYCEROL, GRAM domain-containing protein 1A | 著者 | Fairall, L, Gurnett, J.E, Vashi, D, Sandhu, J, Tontonoz, P, Schwabe, J.W.R. | 登録日 | 2018-06-07 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells. Cell, 175, 2018
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7JQU
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