6NI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ni9 by Molmil](/molmil-images/mine/6ni9) | |
6NJE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nje by Molmil](/molmil-images/mine/6nje) | Crystal structure of the motor domain of human kinesin family member 22 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF22, ... | 著者 | Walker, B.C, Zhu, H, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Park, H, Cochran, J.C, Structural Genomics Consortium (SGC) | 登録日 | 2019-01-03 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the motor domain of human kinesin family member 22 To Be Published
|
|
6NWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nwm by Molmil](/molmil-images/mine/6nwm) | |
6NNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nnx by Molmil](/molmil-images/mine/6nnx) | |
3O8G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o8g by Molmil](/molmil-images/mine/3o8g) | EthR from Mycobacterium tuberculosis in complex with compound BDM14801 | 分子名称: | 1-(azidoacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR | 著者 | Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B. | 登録日 | 2010-08-03 | 公開日 | 2010-09-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. Acs Chem.Biol., 5, 2010
|
|
6NDP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ndp by Molmil](/molmil-images/mine/6ndp) | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP mutant L193Q from Xanthomonas campestris | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Otero, L.H, Sirigu, S, Klinke, S, Rinaldi, J, Conforte, V, Malamud, F, Goldbaum, F.A, Chavas, L, Bonomi, H.R. | 登録日 | 2018-12-14 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.89 Å) | 主引用文献 | Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms. Febs J., 288, 2021
|
|
6NI6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ni6 by Molmil](/molmil-images/mine/6ni6) | |
6NI5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ni5 by Molmil](/molmil-images/mine/6ni5) | |
6NOW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6now by Molmil](/molmil-images/mine/6now) | |
6NNY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nny by Molmil](/molmil-images/mine/6nny) | |
6NWO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nwo by Molmil](/molmil-images/mine/6nwo) | Structures of the transcriptional regulator BgaR, a lactose sensor. | 分子名称: | CHLORIDE ION, GLYCEROL, Transcriptional regulator BgaR, ... | 著者 | Peat, T.S, Newman, J. | 登録日 | 2019-02-06 | 公開日 | 2019-07-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structures of the transcriptional regulator BgaR, a lactose sensor. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6NX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nx3 by Molmil](/molmil-images/mine/6nx3) | |
6NY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ny6 by Molmil](/molmil-images/mine/6ny6) | Structure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-02-11 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
|
|
6NP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6np6 by Molmil](/molmil-images/mine/6np6) | Crystal structure of the sensor domain of the transcriptional regulator HcpR from Porphyromonas Gingivalis | 分子名称: | Crp/Fnr family transcriptional regulator, GLYCEROL | 著者 | Musayev, F.N, Belvin, B.R, Escalante, C.R, Turner, J, Scarsdale, J.N, Lewis, J.P. | 登録日 | 2019-01-17 | 公開日 | 2019-06-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Nitrosative Stress Sensing in Porphyromonas gingivalis: Structure and Mechanisms of the Heme Binding Transcriptional Regulator HcpR. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6NWJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nwj by Molmil](/molmil-images/mine/6nwj) | |
7ACK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ack by Molmil](/molmil-images/mine/7ack) | CDK2/cyclin A2 in complex with an imidazo[1,2-c]pyrimidin-5-one inhibitor | 分子名称: | 1,2-ETHANEDIOL, 8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one, Cyclin-A2, ... | 著者 | Skerlova, J, Pachl, P, Rezacova, P. | 登録日 | 2020-09-11 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure. Eur.J.Med.Chem., 216, 2021
|
|
6NWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nwh by Molmil](/molmil-images/mine/6nwh) | Structures of the transcriptional regulator BgaR, a lactose sensor. | 分子名称: | CHLORIDE ION, MERCURY (II) ION, Transcriptional regulator BgaR, ... | 著者 | Peat, T.S, Newman, J. | 登録日 | 2019-02-06 | 公開日 | 2019-07-17 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structures of the transcriptional regulator BgaR, a lactose sensor. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6NYB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nyb by Molmil](/molmil-images/mine/6nyb) | Structure of a MAPK pathway complex | 分子名称: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Park, E, Rawson, S, Li, K, Jeon, H, Eck, M.J. | 登録日 | 2019-02-11 | 公開日 | 2019-10-09 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
|
|
5TJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tjj by Molmil](/molmil-images/mine/5tjj) | Crystal structure of IcIR transcriptional regulator from Alicyclobacillus acidocaldarius | 分子名称: | GLYCEROL, Transcriptional regulator, IclR family | 著者 | Michalska, K, Mack, J.C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-10-04 | 公開日 | 2016-10-26 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of IcIR transcriptional regulator from Alicyclobacillus acidocaldarius To Be Published
|
|
3SDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdg by Molmil](/molmil-images/mine/3sdg) | Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors. | 分子名称: | 4,4,4-trifluoro-1-{4-[3-(1,3-thiazol-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}butan-1-one, HTH-type transcriptional regulator EthR | 著者 | Flipo, M, Desroses, M, Lecat-Guillet, N, Villemagne, B, Blondiaux, N, Leroux, F, Piveteau, C, Mathys, V, Flament, M.P, Siepmann, J, Villeret, V, Wohlkonig, A, Wintjens, R, Soror, S.H, Christophe, T, Jeon, H.K, Locht, C, Brodin, P, D prez, B, Baulard, A.R, Willand, N. | 登録日 | 2011-06-09 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors. J.Med.Chem., 55, 2012
|
|
5X3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x3r by Molmil](/molmil-images/mine/5x3r) | Crystal structure of the SmcR complexed with QStatin | 分子名称: | 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, LuxR family transcriptional regulator, SULFATE ION | 著者 | Jang, S.Y, Hwang, J, Kim, M.H. | 登録日 | 2017-02-07 | 公開日 | 2018-01-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | QStatin, a Selective Inhibitor of Quorum Sensing inVibrioSpecies MBio, 9, 2018
|
|
2P7V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p7v by Molmil](/molmil-images/mine/2p7v) | Crystal structure of the Escherichia coli regulator of sigma 70, Rsd, in complex with sigma 70 domain 4 | 分子名称: | MAGNESIUM ION, RNA polymerase sigma factor rpoD, Regulator of sigma D | 著者 | Patikoglou, G.A, Westblade, L.F, Campbell, E.A, Lamour, V, Lane, W.J, Darst, S.A. | 登録日 | 2007-03-20 | 公開日 | 2007-08-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the Escherichia coli regulator of sigma70, Rsd, in complex with sigma70 domain 4. J.Mol.Biol., 372, 2007
|
|
7CPU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cpu by Molmil](/molmil-images/mine/7cpu) | Cryo-EM structure of 80S ribosome from mouse kidney | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | 登録日 | 2020-08-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
|
|
7CPV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cpv by Molmil](/molmil-images/mine/7cpv) | Cryo-EM structure of 80S ribosome from mouse testis | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... | 著者 | Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. | 登録日 | 2020-08-08 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
|
|
7UXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uxk by Molmil](/molmil-images/mine/7uxk) | Structure of CDK2 in complex with FP24322, a Helicon Polypeptide | 分子名称: | 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, FP24322, ... | 著者 | Li, K, Agarwal, S, Tokareva, O, Thomson, T, Wahl, S, Verdine, G, McGee, J. | 登録日 | 2022-05-05 | 公開日 | 2022-12-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|