PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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8IYL	Tail tip conformation 2 of phage lambda tail 分子名称: IRON/SULFUR CLUSTER, Tail tip assembly protein I, Tail tip protein L, ... 著者 Wang, J.W, Wang, C. 登録日 2023-04-05 公開日 2023-10-18 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Architecture of the bacteriophage lambda tail. Structure, 32, 2024
3LP3	p15 HIV RNaseH domain with inhibitor MK3 分子名称: 3-[4-(diethylamino)phenoxy]-6-(ethoxycarbonyl)-5,8-dihydroxy-7-oxo-7,8-dihydro-1,8-naphthyridin-1-ium, MANGANESE (II) ION, p15 著者 Yan, Y, Munshi, S.K, Prasad, G.S, Su, H.P. 登録日 2010-02-04 公開日 2010-06-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors. J.Virol., 84, 2010
4EX6	Crystal structure of the alnumycin P phosphatase AlnB 分子名称: AlnB, BORIC ACID, MAGNESIUM ION 著者 Oja, T, Niiranen, L, Sandalova, T, Klika, K.D, Niemi, J, Mantsala, P, Schneider, G, Metsa-Ketela, M. 登録日 2012-04-30 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural basis for C-ribosylation in the alnumycin A biosynthetic pathway. Proc.Natl.Acad.Sci.USA, 110, 2013
7PE9	cryo-EM structure of DEPTOR bound to human mTOR complex 2, DEPt-bound subset local refinement 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEB	cryo-EM structure of DEPTOR bound to human mTOR complex 1, focussed on one protomer 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE8	cryo-EM structure of DEPTOR bound to human mTOR complex 2, focussed on one protomer 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEC	cryo-EM structure of DEPTOR bound to human mTOR complex 1, DEPt-bound subset local refinement 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEA	cryo-EM structure of DEPTOR bound to human mTOR complex 1, overall refinement 分子名称: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PE7	cryo-EM structure of DEPTOR bound to human mTOR complex 2, overall refinement 分子名称: ACETYL GROUP, DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, ... 著者 Waelchli, M, Maier, T. 登録日 2021-08-09 公開日 2021-09-15 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PJ1	Solution structure of isolated Drosophila histone H2A-H2B heterodimer 分子名称: Histone H2A, Histone H2B 著者 van Ingen, H, Zhang, H. 登録日 2021-08-23 公開日 2021-12-08 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Mapping the electrostatic potential of the nucleosome acidic patch. Sci Rep, 11, 2021
7B5N	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1. 分子名称: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
6ID1	Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
5MC6	Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. 登録日 2016-11-09 公開日 2017-01-18 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science, 354, 2016
6GGD	p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9324 分子名称: Cellular tumor antigen p53, GLYCEROL, ZINC ION, ... 著者 Joerger, A.C, Bauer, M.R. 登録日 2018-05-03 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.40000892 Å) 主引用文献 A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
6GGB	p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9318 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cellular tumor antigen p53, ... 著者 Joerger, A.C, Bauer, M.R. 登録日 2018-05-03 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
2VG6	Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors 分子名称: O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-bromophenyl)thiocarbamate, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H 著者 Spallarossa, A, Cesarini, S, Ranise, A, Ponassi, M, Unge, T, Bolognesi, M. 登録日 2007-11-08 公開日 2007-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Crystal Structures of HIV-1 Reverse Transcriptase Complexes with Thiocarbamate Non-Nucleoside Inhibitors. Biochem.Biophys.Res.Commun., 365, 2008
3NBH	Crystal structure of human RMI1C-RMI2 complex 分子名称: RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 著者 Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. 登録日 2010-06-03 公開日 2010-09-22 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
6GGA	p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9284 分子名称: (7-bromanyl-9-ethyl-carbazol-3-yl)methyl-methyl-azanium, Cellular tumor antigen p53, ZINC ION 著者 Joerger, A.C, Bauer, M.R. 登録日 2018-05-03 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.55000126 Å) 主引用文献 A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
6TTU	Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Prabu, J.R, Schulman, B.A. 登録日 2019-12-30 公開日 2020-02-12 最終更新日 2020-03-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly. Nature, 578, 2020
6GGE	p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9327 分子名称: Cellular tumor antigen p53, ZINC ION, [9-ethyl-7-(5-methylthiophen-2-yl)carbazol-3-yl]methyl-methyl-azanium 著者 Joerger, A.C, Bauer, M.R. 登録日 2018-05-03 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.25000513 Å) 主引用文献 A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
6GGC	p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9320 分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, GLYCEROL, ... 著者 Joerger, A.C. 登録日 2018-05-03 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
2X6O	Tet Repressor class D in complex with 7-chlor-2-cyano-iso- tetracycline 分子名称: (4S,4AS,6S,8AS)-6-[(1S)-7-CHLORO-4-HYDROXY-1-METHYL-3-OXO-1,3-DIHYDRO-2-BENZOFURAN-1-YL]-4-(DIMETHYLAMINO)-3,8A-DIHYDROXY-1,8-DIOXO-1,4,4A,5,6,7,8,8A-OCTAHYDRONAPHTHALENE-2-CARBONITRILE, CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS D 著者 Volkers, G, Hinrichs, W. 登録日 2010-02-18 公開日 2011-03-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Recognition of Drug Degradation Products by Target Proteins: Isotetracycline Binding to Tet Repressor. J.Med.Chem., 54, 2011
7KUA	Crystal structure of the MarR family transcriptional regulator from Pseudomonas putida bound to Indole 3 acetic acid 分子名称: 1H-INDOL-3-YLACETIC ACID, Transcriptional regulator, MarR family 著者 Walton, W.G, Lietzan, A.D, Redinbo, M.R, Dangl, J.L. 登録日 2020-11-24 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
2VG5	Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors 分子名称: O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-chlorophenyl)thiocarbamate, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H 著者 Spallarossa, A, Cesarini, S, Ranise, A, Ponassi, M, Unge, T, Bolognesi, M. 登録日 2007-11-08 公開日 2007-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structures of HIV-1 Reverse Transcriptase Complexes with Thiocarbamate Non-Nucleoside Inhibitors. Biochem.Biophys.Res.Commun., 365, 2008
6ICZ	Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... 著者 Zhang, X, Zhan, X, Yan, C, Shi, Y. 登録日 2018-09-07 公開日 2019-03-13 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019

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