PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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5IJD	The crystal structure of mouse TLR4/MD-2/lipid A complex 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. 登録日 2016-03-01 公開日 2016-04-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS. Proc.Natl.Acad.Sci.USA, 113, 2016
1KI7	CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-IODODEOXYURIDINE 分子名称: 5-IODODEOXYURIDINE, SULFATE ION, THYMIDINE KINASE 著者 Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Summers, W.C, Sanderson, M.R. 登録日 1998-05-15 公開日 1998-12-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins, 32, 1998
1RM6	Structure of 4-hydroxybenzoyl-CoA reductase from Thauera aromatica 分子名称: (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-hydroxybenzoyl-CoA reductase alpha subunit, ... 著者 Unciuleac, M, Warkentin, E, Page, C.C, Dutton, P.L, Boll, M, Ermler, U. 登録日 2003-11-27 公開日 2004-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a Xanthine Oxidase-Related 4-Hydroxybenzoyl-CoA Reductase with an Additional [4Fe-4S] Cluster and an Inverted Electron Flow Structure, 12, 2004
5IJT	Human Peroxiredoxin 2 Oxidized (SS) 分子名称: Peroxiredoxin-2, ZINC ION 著者 Haynes, A.C, Bolduc, J.A, Lowther, W.T. 登録日 2016-03-02 公開日 2017-09-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.148 Å) 主引用文献 Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. J. Biol. Chem., 293, 2018
1KIM	CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH DEOXYTHYMIDINE 分子名称: SULFATE ION, THYMIDINE, THYMIDINE KINASE 著者 Champness, J.N, Bennett, M.S, Wien, F, Brown, D.G, Visse, R, Sandhu, G, Davies, A, Rizkallah, P.J, Melitz, C, Summers, W.C, Sanderson, M.R. 登録日 1997-11-12 公開日 1998-05-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins, 32, 1998
5IG9	Crystal structure of macrocyclase MdnC bound with precursor peptide MdnA from Microcystis aeruginosa MRC 分子名称: ATP grasp ligase, Microviridin 著者 Li, K, Condurso, H.L, Bruner, S.D. 登録日 2016-02-27 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.665 Å) 主引用文献 Structural basis for precursor protein-directed ribosomal peptide macrocyclization. Nat.Chem.Biol., 12, 2016
1RPL	2.3 ANGSTROMS CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF DNA POLYMERASE BETA 分子名称: DNA POLYMERASE BETA 著者 Davies II, J.F, Almassy, R.J. 登録日 1994-10-25 公開日 1995-01-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 2.3 A crystal structure of the catalytic domain of DNA polymerase beta. Cell(Cambridge,Mass.), 76, 1994
1KWJ	solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans, minimized average structure 分子名称: HEME C, cytochrome c7 著者 Assfalg, M, Bertini, I, Turano, P, Bruschi, M, Durand, M.C, Giudici-Orticoni, M.T, Dolla, A. 登録日 2002-01-29 公開日 2002-02-06 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A quick solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans and mechanistic implications. J.Biomol.NMR, 22, 2002
5IK1	Open state of P450cam after soaking in camphor 分子名称: CAMPHOR, Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Mahomed, M, Goodin, D.B, Lee, Y.-T. 登録日 2016-03-03 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States. J.Am.Chem.Soc., 138, 2016
1RDM	MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-D-MANNOPYRANOSIDE (1.3 M) 分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ... 著者 Ng, K.K.-S, Drickamer, K, Weis, W.I. 登録日 1995-09-05 公開日 1996-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of monosaccharide recognition by rat liver mannose-binding protein. J.Biol.Chem., 271, 1996
1RDI	MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT COMPLEX WITH ALPHA-METHYL-L-FUCOPYRANOSIDE 分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C, ... 著者 Ng, K.K.-S, Drickamer, K, Weis, W.I. 登録日 1995-09-05 公開日 1996-03-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural analysis of monosaccharide recognition by rat liver mannose-binding protein. J.Biol.Chem., 271, 1996
1KQY	Hevamine Mutant D125A/E127A/Y183F in Complex with Penta-NAG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hevamine A, ... 著者 Rozeboom, H.J, Dijkstra, B.W. 登録日 2002-01-08 公開日 2002-01-23 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis. Eur.J.Biochem., 269, 2002
5IP0	PHA Binding Protein PhaP (Phasin) 分子名称: CADMIUM ION, PHA granule-associated protein 著者 Chen, G.Q, Wang, X.Q, Zhao, H.Y. 登録日 2016-03-09 公開日 2017-01-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila Sci Rep, 6, 2016
5ISL	Linked KDM5A Jmj Domain Bound to the Inhibitor C49 (2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid) 分子名称: 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2016-03-15 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol, 23, 2016
1RIQ	The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase 分子名称: Alanyl-tRNA synthetase 著者 Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. 登録日 2003-11-17 公開日 2004-04-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition Mol.Cell, 13, 2004
1RN4	HIS92ALA MUTATION IN RIBONUCLEASE T1 INDUCES SEGMENTAL FLEXIBILITY. AN X-RAY STUDY 分子名称: PHOSPHATE ION, RIBONUCLEASE T1 著者 Saenger, W, Koellner, G. 登録日 1991-11-07 公開日 1993-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 His92Ala mutation in ribonuclease T1 induces segmental flexibility. An X-ray study. J.Mol.Biol., 224, 1992
1RND	NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE 分子名称: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE A, SULFATE ION 著者 Aguilar, C.F, Thomas, P.J, Mills, A, Moss, D.S, Palmer, R.A. 登録日 1991-10-21 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Newly observed binding mode in pancreatic ribonuclease. J.Mol.Biol., 224, 1992
5IRC	p190A GAP domain complex with RhoA 分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Derewenda, U, Derewenda, Z. 登録日 2016-03-12 公開日 2016-08-17 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. J.Biol.Chem., 291, 2016
5ISP	Staphylococcus aureus F98Y Dihydrofolate Reductase mutant complexed with beta-NADPH and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-4'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (UCP1106) 分子名称: 4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-4-methoxy-phenyl]benzoic acid, Dihydrofolate reductase, GLYCEROL, ... 著者 Anderson, A.C, Reeve, S.M. 登録日 2016-03-15 公開日 2017-06-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations. J. Med. Chem., 59, 2016
5K7W	Crystal structure of the catalytic domain of Mettl3/Mettl14 complex with SAH 分子名称: N6-adenosine-methyltransferase 70 kDa subunit, N6-adenosine-methyltransferase subunit METTL14, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wang, P, Doxtader, K.A, Nam, Y. 登録日 2016-05-26 公開日 2016-07-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Mol.Cell, 63, 2016
1LK3	ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT 分子名称: 9D7 Heavy Chain, 9D7 Light Chain, Interleukin-10 著者 Josephson, K, Jones, B.C, Walter, L.J, DiGiacomo, R, Indelicato, S.R, Walter, M.R. 登録日 2002-04-23 公開日 2002-07-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography. Structure, 10, 2002
5JXG	Structure of the unliganded form of the proprotein convertase furin. 分子名称: CALCIUM ION, CHLORIDE ION, Furin, ... 著者 Dahms, S.O, Arciniega, M, Steinmetzer, T, Huber, R, Than, M.E. 登録日 2016-05-13 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
1LL4	STRUCTURE OF C. IMMITIS CHITINASE 1 COMPLEXED WITH ALLOSAMIDIN 分子名称: 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, CHITINASE 1 著者 Bortone, K, Monzingo, A.F, Ernst, S, Robertus, J.D. 登録日 2002-04-26 公開日 2002-09-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 THE STRUCTURE OF AN ALLOSAMIDIN COMPLEX WITH THE Coccidioides IMMITIS CHITINASE DEFINES A ROLE FOR A SECOND ACID RESIDUE IN SUBSTRATE-ASSISTED MECHANISM J.Mol.Biol., 320, 2002
5JZQ	Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals massive presence of multiple conformations 分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION 著者 Drozdzal, P, Gilski, M, Jaskolski, M. 登録日 2016-05-17 公開日 2016-11-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (0.78 Å) 主引用文献 Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations. Acta Crystallogr D Struct Biol, 72, 2016
5JZY	Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-cyclohexyl-D-alanyl-N-[(4-carbamimidoylphenyl)methyl]-L-prolinamide, DIMETHYL SULFOXIDE, ... 著者 Sandner, A, Heine, A, Klebe, G. 登録日 2016-05-17 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019

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