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5I1I
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV4-1
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN
著者Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
登録日2016-02-05
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I00
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tRNA guanine transglycosylase (TGT) in co-crystallized complex with 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
分子名称: 1,2-ETHANEDIOL, 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, CHLORIDE ION, ...
著者Ehrmann, F.R, Heine, A, Klebe, G.
登録日2016-02-03
公開日2017-02-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Co-crystallization, Isothermal titration calorimetry and nanoESI-MS reveal dimer disturbing inhibitors
To be Published
5I1L
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CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV4-1
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL
著者Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
登録日2016-02-05
公開日2016-06-08
最終更新日2016-08-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural diversity in a human antibody germline library.
Mabs, 8, 2016
1JAL
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YCHF PROTEIN (HI0393)
分子名称: YchF protein
著者Teplyakov, A, Gilliland, G.L, Structure 2 Function Project (S2F)
登録日2001-05-30
公開日2003-03-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the YchF protein reveals binding sites for GTP and nucleic acid
J.BACTERIOL., 185, 2003
5I2C
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Arginine-bound CASTOR1 from Homo sapiens
分子名称: ACETATE ION, ARGININE, GATS-like protein 3
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2016-02-08
公開日2016-08-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Nature, 536, 2016
1JDB
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CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI
分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE, CHLORIDE ION, ...
著者Thoden, J.B, Holden, H.M, Wesenberg, G, Raushel, F.M, Rayment, I.
登録日1997-03-25
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1JI6
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CRYSTAL STRUCTURE OF THE INSECTICIDAL BACTERIAL DEL ENDOTOXIN CRY3Bb1 BACILLUS THURINGIENSIS
分子名称: PESTICIDIAL CRYSTAL PROTEIN CRY3BB
著者Cody, V.
登録日2001-06-29
公開日2001-09-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the insecticidal bacterial delta-endotoxin Cry3Bb1 of Bacillus thuringiensis.
Acta Crystallogr.,Sect.D, 57, 2001
1RZT
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Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule
分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*G)-3', ...
著者Pedersen, L.C, Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Blanco, L, Kunkel, T.A.
登録日2003-12-29
公開日2004-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology.
Mol.Cell, 13, 2004
1JJJ
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SOLUTION STRUCTURE OF RECOMBINANT HUMAN EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN
分子名称: EPIDERMAL-TYPE FATTY ACID BINDING PROTEIN (E-FABP)
著者Gutierrez-Gonzalez, L.H, Ludwig, C, Hohoff, C, Rademacher, M, Hanhoff, T, Rueterjans, H, Spener, F, Luecke, C.
登録日2001-07-06
公開日2002-06-19
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP)
BIOCHEM.J., 364, 2002
5I7O
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Mycobacterium tuberculosis CysM in complex with the Urea-scaffold inhibitor 7 [3-(3-(4-Chlorophenyl)ureido)benzoic acid]
分子名称: 3-{[(4-chlorophenyl)carbamoyl]amino}benzoic acid, O-phosphoserine sulfhydrylase, PYRIDOXAL-5'-PHOSPHATE
著者Schnell, R, Maric, S, Schneider, G.
登録日2016-02-18
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
J.Med.Chem., 59, 2016
5I8U
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Crystal Structure of the RV1700 (MT ADPRASE) E142Q mutant
分子名称: ADP-ribose pyrophosphatase, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
著者Thirawatananond, P, Kang, L.-W, Amzel, L.M, Gabelli, S.B.
登録日2016-02-19
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis.
J. Bioenerg. Biomembr., 48, 2016
1JQY
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HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH LIGAND BMSC-0010
分子名称: (3-NITRO-5-(3-MORPHOLIN-4-YL-PROPYLAMINOCARBONYL)PHENYL)-GALACTOPYRANOSIDE, HEAT-LABILE ENTEROTOXIN B CHAIN
著者Merritt, E.A, Hol, W.G.J.
登録日2001-08-09
公開日2002-05-08
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Anchor-based design of improved cholera toxin and E. coli heat-labile enterotoxin receptor binding antagonists that display multiple binding modes.
Chem.Biol., 9, 2002
1S7X
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Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
1JRP
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Crystal Structure of Xanthine Dehydrogenase inhibited by alloxanthine from Rhodobacter capsulatus
分子名称: CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Truglio, J.J, Theis, K, Leimkuhler, S, Rappa, R, Rajagopalan, K.V, Kisker, C.
登録日2001-08-14
公開日2002-01-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of the active and alloxanthine-inhibited forms of xanthine dehydrogenase from Rhodobacter capsulatus
Structure, 10, 2002
1SCE
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CRYSTAL STRUCTURE OF THE CELL CYCLE REGULATORY PROTEIN SUC1 REVEALS A NOVEL BETA-HINGE CONFORMATIONAL SWITCH
分子名称: CHLORIDE ION, SUC1
著者Bourne, Y, Tainer, J.A.
登録日1995-05-11
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch.
Proc.Natl.Acad.Sci.USA, 92, 1995
5IFM
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Human NONO (p54nrb) Homodimer
分子名称: CHLORIDE ION, GLYCEROL, Non-POU domain-containing octamer-binding protein, ...
著者Knott, G.J, Bond, C.S.
登録日2016-02-26
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry.
Acta Crystallogr D Struct Biol, 72, 2016
1KME
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CRYSTAL STRUCTURE OF BACTERIORHODOPSIN CRYSTALLIZED FROM BICELLES
分子名称: 2,10,23-TRIMETHYL-TETRACOSANE, Bacteriorhodopsin, RETINAL, ...
著者Faham, S, Bowie, J.U.
登録日2001-12-14
公開日2002-02-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bicelle crystallization: a new method for crystallizing membrane proteins yields a monomeric bacteriorhodopsin structure.
J.Mol.Biol., 316, 2002
1KVZ
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Solution Structure of Cytotoxic RC-RNase4
分子名称: RC-RNase4
著者Hsu, C.-H, Liao, Y.-D, Chen, L.-W, Wu, S.-H, Chen, C.
登録日2002-01-28
公開日2002-07-28
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献Solution Structure of the Cytotoxic RNase 4 from the Oocytes of Bullfrog Rana Catesbeiana
J.MOL.BIOL., 326, 2003
1RA5
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Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.
分子名称: (4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE, Cytosine deaminase, FE (III) ION, ...
著者Mahan, S.D, Ireton, G.C, Stoddard, B.L, Black, M.E.
登録日2003-10-31
公開日2004-10-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy.
Protein Eng.Des.Sel., 17, 2004
1KVQ
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UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH UDP-PHENOL
分子名称: 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ...
著者Thoden, J.B, Gulick, A.M, Holden, H.M.
登録日1997-03-07
公開日1998-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry, 36, 1997
1RDO
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MANNOSE-BINDING PROTEIN, SUBTILISIN DIGEST FRAGMENT
分子名称: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-C
著者Ng, K.K.-S, Drickamer, K, Weis, W.I.
登録日1995-09-05
公開日1996-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural analysis of monosaccharide recognition by rat liver mannose-binding protein.
J.Biol.Chem., 271, 1996
1R3N
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Crystal structure of beta-alanine synthase from Saccharomyces kluyveri
分子名称: BETA-AMINO ISOBUTYRATE, ZINC ION, beta-alanine synthase
著者Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D.
登録日2003-10-02
公開日2003-11-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278, 2003
5IRO
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Crystal structure of a complex between the Human adenovirus type 4 E3-19K protein and MHC class molecule HLA-A2/TAX
分子名称: Beta-2-microglobulin, E3 19 kDa protein, HLA class I histocompatibility antigen, ...
著者Li, L, Bouvier, M.
登録日2016-03-14
公開日2016-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of the Adenovirus Type 4 (Species E) E3-19K/HLA-A2 Complex Reveals Species-Specific Features in MHC Class I Recognition.
J Immunol., 197, 2016
1KUU
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CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
分子名称: conserved protein
著者Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F.
登録日2002-01-22
公開日2002-05-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD
PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
5IEY
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Crystal structure of a CDK inhibitor bound to CDK2
分子名称: 4-[(4-{[(2R,3R)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide, Cyclin-dependent kinase 2
著者Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M.
登録日2016-02-25
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol., 11, 2016

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