8Y2H
 
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9FEE
 | | Cryo-EM structure of Trypanosoma cruzi glycosomal malate dehydrogenase | | 分子名称: | malate dehydrogenase | | 著者 | Lipinski, O, Sonani, R.R, Blat, A, Jemiola-Rzeminska, M, Patel, S.N, Sood, T, Dubin, G. | | 登録日 | 2024-05-19 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Cryo-EM structure of Trypanosoma cruzi glycosomal malate dehydrogenase
To Be Published
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8ZMU
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9B3Q
 | | The structure of the human cardiac F-actin mutant A331P | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | 著者 | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | | 登録日 | 2024-03-20 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of human cardiac actin
To Be Published
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8OJR
 | | Solution NMR Structure of Alpha-Synuclein 1-25 Peptide in 50% TFE. | | 分子名称: | Alpha-synuclein | | 著者 | Allen, S.G, Williams, C, Meade, R.M, Tang, T.M.S, Crump, M.P, Mason, J.M. | | 登録日 | 2023-03-24 | | 公開日 | 2023-08-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An N-terminal alpha-Synuclein fragment binds lipid vesicles to modulate lipid induced aggregation
Cell Rep Phys Sci, 2023
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8XKG
 | | Crystal structure of Acinetobacter baumannii IspD | | 分子名称: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, GLYCEROL | | 著者 | Chen, X, Wu, D. | | 登録日 | 2023-12-23 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents, 63, 2024
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8YB5
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9IIW
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8W0U
 | | Human LCAD complexed with Acetoacetyl Coenzyme A | | 分子名称: | ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE, Long-chain specific acyl-CoA dehydrogenase, ... | | 著者 | Xia, C, Kim, J.J.P. | | 登録日 | 2024-02-14 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.
Sci Rep, 14, 2024
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9AZP
 | | INF2 at the Barbed End of F-Actin with Incoming Profilin-Actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Palmer, N.J, Barrie, K.R, Dominguez, R. | | 登録日 | 2024-03-11 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Mechanisms of actin filament severing and elongation by formins.
Nature, 632, 2024
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8OZV
 | | Imine Reductase from Ajellomyces dermatitidis in complex with 2,2-difluoroacetophenone | | 分子名称: | 2,2-bis(fluoranyl)-1-phenyl-ethanone, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase | | 著者 | Sharma, M, Grogan, G. | | 登録日 | 2023-05-09 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms.
Acta Crystallogr.,Sect.F, 79, 2023
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9ILD
 | | Complex structure of Cap3 and CD-NTase | | 分子名称: | Cyclic GMP-AMP synthase, Peptidase, ZINC ION | | 著者 | Li, F.Q, Ma, W.F. | | 登録日 | 2024-06-29 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.179 Å) | | 主引用文献 | Structural and functional characterization of the bacterial Cap3 enzyme in deconjugation and regulation of the cyclic dinucleotide transferase CD-NTase
To Be Published
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8YUA
 | | Tubulin-RB3-TTL in complex with compound SI10 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-~{N}-(4-methoxyphenyl)-~{N}-methyl-thieno[3,2-d]pyrimidin-4-amine, CALCIUM ION, ... | | 著者 | Wu, C.Y, Wang, Y.X. | | 登録日 | 2024-03-27 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | The complex structure of tubulin-RB3-TTL in complex with compound SI10
To Be Published
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8ZB8
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9EMC
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8XHU
 | | Crystal structure of Helicobacter pylori IspDF | | 分子名称: | 1,2-ETHANEDIOL, Bifunctional enzyme IspD/IspF, CHLORIDE ION, ... | | 著者 | Chen, X, Wu, D. | | 登録日 | 2023-12-18 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents, 63, 2024
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9BUJ
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8XZ7
 | | FGFR1 kinase domain with a covalent inhibitor 10h | | 分子名称: | 5-azanyl-3-[2-[4,6-bis(fluoranyl)-2-methyl-3~{H}-benzimidazol-5-yl]ethynyl]-1-[[3-(prop-2-enoylamino)phenyl]methyl]pyrazole-4-carboxamide, Fibroblast growth factor receptor 1, SULFATE ION | | 著者 | Chen, X.J, Chen, Y.H. | | 登録日 | 2024-01-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4-carboxamide derivatives as pan-FGFR covalent inhibitors.
Eur.J.Med.Chem., 275, 2024
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9BNJ
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8OM1
 | | Mitochondrial complex I from Mus musculus in the active state | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. | | 登録日 | 2023-03-31 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
Sci Adv, 9, 2023
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8XOW
 | | Mature virion portal of bacteriophage lambda | | 分子名称: | Head completion protein, Head-tail connector protein FII, Portal protein B, ... | | 著者 | Wang, J.W, Gu, Z.W. | | 登録日 | 2024-01-02 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
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8WIJ
 | | Crystal structure of E. coli ThrS catalytic domain mutant L489M in complex with Obafluorin | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Wang, Z, Wang, J, Fang, P. | | 登録日 | 2023-09-24 | | 公開日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Specific glycine-dependent enzyme motion determines the potency of conformation selective inhibitors of threonyl-tRNA synthetase.
Commun Biol, 7, 2024
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8ORI
 | | Crystal structure of Rhizobium etli L-asparaginase ReAIV (orthorhombic) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Loch, J.I, Worsztynowicz, P, Sliwiak, J, Imiolczyk, B, Grzechowiak, M, Gilski, M, Jaskolski, M. | | 登録日 | 2023-04-14 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Rhizobium etli has two L-asparaginases with low sequence identity but similar structure and catalytic center.
Acta Crystallogr D Struct Biol, 79, 2023
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9FT1
 | | Yeast 20S proteasome in complex with epoxyketone inhibitor 13 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... | | 著者 | Maurits, E, Huber, E.M, Dekker, P.M, Wang, X, Heinemeyer, W, Florea, B.I, Groll, M, Overkleeft, H.S. | | 登録日 | 2024-06-23 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites
to be published
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8YTQ
 | | The structure of apoCopC from Thioalkalivibrio paradoxus | | 分子名称: | ACETATE ION, COPPER (II) ION, CopC domain-containing protein, ... | | 著者 | Kulikova, O.G, Solovieva, A.Y, Varfolomeeva, L.A, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O. | | 登録日 | 2024-03-26 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structure of apoCopC from Thioalkalivibrio paradoxus
To Be Published
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