PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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2MWZ	Xanthine and 8-oxoguanine in G-quadruplexes: formation of a G G X O tetrad 分子名称: DNA (5'-D(*TP*TP*GP*GP*GP*TP*TP*AP*(8OG)P*GP*GP*TP*TP*AP*GP*GP*(3ZO)P*TP*TP*AP*GP*GP*GP*A)-3') 著者 Cheong, V.V, Heddi, B, Lech, C.J, Phan, A.T. 登録日 2014-12-04 公開日 2015-10-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Xanthine and 8-oxoguanine in G-quadruplexes: formation of a GGXO tetrad. Nucleic Acids Res., 43, 2015
4IRK	structure of Polymerase-DNA complex, dna 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*A*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*C)-3'), ... 著者 Nair, D.T, Sharma, A. 登録日 2013-01-14 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli. Nucleic Acids Res., 41, 2013
3A7A	Crystal structure of E. coli lipoate-protein ligase A in complex with octyl-amp and apoH-protein 分子名称: ADENOSINE MONOPHOSPHATE, Glycine cleavage system H protein, Lipoate-protein ligase A, ... 著者 Fujiwara, K, Hosaka, H, Nakagawa, A. 登録日 2009-09-20 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Global conformational change associated with the two-step reaction catalyzed by Escherichia coli lipoate-protein ligase A. J.Biol.Chem., 285, 2010
2ISH	Botulinum Neurotoxin A Light Chain WT Crystal Form C 分子名称: Neurotoxin BoNT/A, ZINC ION 著者 Brunger, A.T, Stegmann, C.M. 登録日 2006-10-17 公開日 2006-11-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J.Biol.Chem., 282, 2007
1CCI	HOW FLEXIBLE ARE PROTEINS? TRAPPING OF A FLEXIBLE LOOP 分子名称: 2,3-DIMETHYLIMIDAZOLIUM ION, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Cao, Y, Musah, R.A, Wilcox, S.K, Goodin, D.B, Mcree, D.E. 登録日 1996-12-18 公開日 1997-07-07 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity. Nat.Struct.Biol., 3, 1996
2IDN	NMR structure of a new modified Thrombin Binding Aptamer containing a 5'-5' inversion of polarity site 分子名称: 3'-D(P*GP*G*T)-5'-5'-D(P*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3' 著者 Randazzo, A, Martino, L, Virno, A, Mayol, L, Giancola, C. 登録日 2006-09-15 公開日 2007-01-09 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site. Nucleic Acids Res., 34, 2006
1C0C	BOVINE PANCREATIC RIBONUCLEASE A DESICCATED FOR 4.0 DAYS 分子名称: RIBONUCLEASE A, SULFATE ION 著者 Bell, J.A. 登録日 1999-07-15 公開日 1999-10-14 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystal structures of a severely desiccated protein Protein Sci., 8, 1999
1RZT	Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule 分子名称: 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*G)-3', ... 著者 Pedersen, L.C, Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Blanco, L, Kunkel, T.A. 登録日 2003-12-29 公開日 2004-03-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol.Cell, 13, 2004
1S1J	Crystal Structure of ZipA in complex with indoloquinolizin inhibitor 1 分子名称: (12bS)-1,2,3,4,12,12b-hexahydroindolo[2,3-a]quinolizin-7(6H)-one, Cell division protein zipA 著者 Jenning, L.D, Foreman, K.W, Rush III, T.S, Tsao, D.H, Mosyak, L, Li, Y, Sukhdeo, M.N, Ding, W, Dushin, E.G, Kenney, C.H, Moghazeh, S.L, Peterson, P.J, Ruzin, A.V, Tuckman, M, Sutherland, A.G. 登録日 2004-01-06 公開日 2004-05-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction Bioorg.Med.Chem.Lett., 14, 2004
4JPG	2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as Novel PKM2 Activators 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 2-(1H-benzimidazol-1-ylmethyl)-4H-pyrido[1,2-a]pyrimidin-4-one, Pyruvate kinase isozymes M1/M2 著者 Greasley, S.E, Hickey, M, Phonephaly, H, Cronin, C. 登録日 2013-03-19 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators. Bioorg.Med.Chem.Lett., 23, 2013
1YMW	The study of reductive unfolding pathways of RNase A (Y92G mutant) 分子名称: Ribonuclease pancreatic 著者 Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. 登録日 2005-01-21 公開日 2006-01-31 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
1YMR	The study of reductive unfolding pathways of RNase A (Y92A mutant) 分子名称: Ribonuclease pancreatic 著者 Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. 登録日 2005-01-21 公開日 2006-01-31 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
1YMN	The study of reductive unfolding pathways of RNase A (Y92L mutant) 分子名称: Ribonuclease pancreatic 著者 Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. 登録日 2005-01-21 公開日 2006-01-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
1B2Z	DELETION OF A BURIED SALT BRIDGE IN BARNASE 分子名称: PROTEIN (BARNASE), ZINC ION 著者 Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. 登録日 1998-12-03 公開日 1998-12-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
1BCJ	MANNOSE-BINDING PROTEIN-A MUTANT (QPDWGHV) COMPLEXED WITH N-ACETYL-D-GALACTOSAMINE 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Kolatkar, A.R, Weis, W.I. 登録日 1998-04-30 公開日 1998-06-17 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain. J.Biol.Chem., 273, 1998
1ARL	CARBOXYPEPTIDASE A WITH ZN REMOVED 分子名称: APO-CARBOXYPEPTIDASE A=ALPHA= (COX) 著者 Greenblatt, H.M, Feinberg, H, Tucker, P.A, Shoham, G. 登録日 1994-11-22 公開日 1996-08-01 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Carboxypeptidase A: native, zinc-removed and mercury-replaced forms. Acta Crystallogr.,Sect.D, 54, 1998
2BXS	Human Monoamine Oxidase A in complex with Clorgyline, Crystal Form B 分子名称: AMINE OXIDASE [FLAVIN-CONTAINING] A, FLAVIN-ADENINE DINUCLEOTIDE, N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE 著者 De Colibus, L, Binda, C, Edmondson, D.E, Mattevi, A. 登録日 2005-07-27 公開日 2005-08-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B Proc.Natl.Acad.Sci.USA, 102, 2005
1RD6	Crystal Structure of S. Marcescens Chitinase A Mutant W167A 分子名称: Chitinase A 著者 Aronson, N.N, Halloran, B.A, Alexyev, M.F, Zhou, X.E, Wang, Y, Meehan, E.J, Chen, L. 登録日 2003-11-05 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mutation of a conserved tryptophan in the chitin-binding cleft of Serratia marcescens chitinase A enhances transglycosylation. Biosci.Biotechnol.Biochem., 70, 2006
1B2V	HEME-BINDING PROTEIN A 分子名称: CALCIUM ION, PROTEIN (HEME-BINDING PROTEIN A), PROTOPORPHYRIN IX CONTAINING FE 著者 Arnoux, P, Haser, R, Izadi, N, Lecroisey, A, Wandersma, N.C, Czjzek, M. 登録日 1998-12-01 公開日 1999-06-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of HasA, a hemophore secreted by Serratia marcescens. Nat.Struct.Biol., 6, 1999
1KWJ	solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans, minimized average structure 分子名称: HEME C, cytochrome c7 著者 Assfalg, M, Bertini, I, Turano, P, Bruschi, M, Durand, M.C, Giudici-Orticoni, M.T, Dolla, A. 登録日 2002-01-29 公開日 2002-02-06 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 A quick solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans and mechanistic implications. J.Biomol.NMR, 22, 2002
1XKK	EGFR kinase domain complexed with a quinazoline inhibitor- GW572016 分子名称: Epidermal growth factor receptor, N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE, PHOSPHATE ION 著者 Wood, E.R, Truesdale, A.T, McDonald, O.B, Yuan, D, Hassell, A, Dickerson, S.H, Ellis, B, Pennisi, C, Horne, E, Lackey, K, Alligood, K.J, Rusnak, D.W, Gilmer, T.M, Shewchuk, L.M. 登録日 2004-09-29 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res., 64, 2004
3B8D	Fructose 1,6-bisphosphate aldolase from rabbit muscle 分子名称: Fructose-bisphosphate aldolase A, SULFATE ION 著者 Maurady, A, Sygusch, J. 登録日 2007-11-01 公開日 2007-11-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases. J.Biol.Chem., 277, 2002
3B9D	Crystal structure of Vibrio harveyi chitinase A complexed with pentasaccharide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase A 著者 Songsiriritthigul, C, Aguda, A.H, Robinson, R.C, Suginta, W. 登録日 2007-11-05 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Crystal structures of Vibrio harveyi chitinase A complexed with chitooligosaccharides: implications for the catalytic mechanism J.Struct.Biol., 162, 2008
4NQM	Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand 分子名称: 2-chloro-N-[5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-2-(morpholin-4-yl)phenyl]benzenesulfonamide, Bromodomain-containing protein 4, SUCCINIC ACID 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Martin, S, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-11-25 公開日 2013-12-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal Structure of the first bromodomain of human BRD4 in complex with a triazolo-phthalazine ligand To be Published
1L3Q	H. rufescens abalone shell Lustrin A consensus repeat, FPGKNVNCTSGE, pH 7.4, 1-H NMR structure 分子名称: Lustrin A 著者 Evans, J.S, Wustman, B.A, Zhang, B, Morse, D.E. 登録日 2002-02-28 公開日 2002-03-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Model peptide studies of sequence regions in the elastomeric biomineralization protein, Lustrin A. I. The C-domain consensus-PG-, -NVNCT-motif Biopolymers, 63, 2002

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