PDB: 5495 件ウェブページステータス検索Chemie searchBIRD

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3I7H	Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX 分子名称: DNA damage-binding protein 1, X protein 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-08 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
3IUC	Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 5 (Glucose-regulated protein, ... 著者 Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) 登録日 2009-08-31 公開日 2009-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5, 2010
3R21	Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I) 分子名称: MAGNESIUM ION, N-(2-aminoethyl)-N-{5-[(1-cycloheptyl-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino]pyridin-2-yl}methanesulfonamide, Serine/threonine-protein kinase 6 著者 Zhang, L, Fan, J, Chong, J.-H, Cesena, A, Tam, B, Gilson, C, Boykin, C, Wang, D, Marcotte, D, Le Brazidec, J.-Y, Aivazian, D, Piao, J, Lundgren, K, Hong, K, Vu, K, Nguyen, K. 登録日 2011-03-11 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I). Bioorg.Med.Chem.Lett., 21, 2011
3I7L	Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2 分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-08 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
1AXC	HUMAN PCNA 分子名称: P21/WAF1, PCNA 著者 Gulbis, J.M, Kuriyan, J. 登録日 1997-10-14 公開日 1998-01-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA. Cell(Cambridge,Mass.), 87, 1996
3RLO	Structural Basis of Cytosolic DNA Recognition by Innate Receptors 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Gamma-interferon-inducible protein 16 著者 Jin, T.C, Xiao, T. 登録日 2011-04-19 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor. Immunity, 36, 2012
1BCY	RECOMBINANT RAT ANNEXIN V, T72K MUTANT 分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. 登録日 1998-05-04 公開日 1998-11-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
3IU5	Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) 分子名称: Protein polybromo-1 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2009-08-30 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3I7K	Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX 分子名称: DNA damage-binding protein 1, X protein 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-08 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
3I8E	Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A 分子名称: DNA damage-binding protein 1, WD repeat-containing protein 42A 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-09 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
1BCK	HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN 分子名称: CYCLOSPORIN C, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A 著者 Mikol, V, Kallen, J, Taylor, P, Walkinshaw, M.D. 登録日 1998-04-30 公開日 1998-09-16 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-Ray Structures and Analysis of 11 Cyclosporin Derivatives Complexed with Cyclophilin A. J.Mol.Biol., 283, 1998
1B64	SOLUTION STRUCTURE OF THE GUANINE NUCLEOTIDE EXCHANGE FACTOR DOMAIN FROM HUMAN ELONGATION FACTOR-ONE BETA, NMR, 20 STRUCTURES 分子名称: ELONGATION FACTOR 1-BETA 著者 Perez, J.M.J, Siegal, G, Kriek, J, Hard, K, Dijk, J, Canters, G.W, Moller, W. 登録日 1999-01-20 公開日 1999-05-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure of the guanine nucleotide exchange domain of human elongation factor 1beta reveals a striking resemblance to that of EF-Ts from Escherichia coli. Structure Fold.Des., 7, 1999
1BFS	STRUCTURE OF NF-KB P50 HOMODIMER BOUND TO A KB SITE 分子名称: NUCLEAR FACTOR NF-KAPPA-B P50 著者 Huang, D.B, Huxford, T, Chen, Y.Q, Ghosh, G. 登録日 1997-09-12 公開日 1998-01-28 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits. Structure, 5, 1997
3PSL	Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic 分子名称: N-alpha acetylated form of histone H3, WD repeat-containing protein 5 著者 Avdic, V, Zhang, P, Lanouette, S, Voronova, A, Skerjanc, I, Couture, J.-F. 登録日 2010-12-01 公開日 2010-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic. Faseb J., 25, 2011
1BG2	HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, KINESIN, ... 著者 Kull, F.J, Sablin, E.P, Lau, R, Fletterick, R.J, Vale, R.D. 登録日 1998-06-04 公開日 1998-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature, 380, 1996
3I89	Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22 分子名称: DNA damage-binding protein 1, WD repeat-containing protein 22 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-09 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
3QSV	Structural basis for DNA recognition by constitutive Smad4 MH1 dimers 分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 4, ZINC ION 著者 Baburajendran, N, Jauch, R, Zhen, C.T.Y, Kolatkar, P.R. 登録日 2011-02-22 公開日 2011-06-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.708 Å) 主引用文献 Structural basis for DNA recognition by constitutive Smad4 MH1 dimers To be Published
1BC1	RECOMBINANT RAT ANNEXIN V, QUADRUPLE MUTANT (T72K, S144K, S228K, S303K) 分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. 登録日 1998-05-04 公開日 1998-11-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1BCZ	RECOMBINANT RAT ANNEXIN V, T72S MUTANT 分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. 登録日 1998-05-04 公開日 1998-11-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1BCW	RECOMBINANT RAT ANNEXIN V, T72A MUTANT 分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. 登録日 1998-05-04 公開日 1998-11-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1BC3	RECOMBINANT RAT ANNEXIN V, TRIPLE MUTANT (T72K, S144K, S228K) 分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION 著者 Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. 登録日 1998-05-04 公開日 1998-11-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1AP0	STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES 分子名称: MODIFIER PROTEIN 1 著者 Ball, L.J, Murzina, N.V, Broadhurst, R.W, Raine, A.R.C, Archer, S.J, Stott, F.J, Murzin, A.G, Singh, P.B, Domaille, P.J, Laue, E.D. 登録日 1997-07-22 公開日 1998-07-22 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the chromatin binding (chromo) domain from mouse modifier protein 1. EMBO J., 16, 1997
3IJ1	Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide 分子名称: Histone H4K20 peptide, Polycomb protein EED 著者 Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. 登録日 2009-08-03 公開日 2009-09-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
1AWU	CYPA COMPLEXED WITH HVGPIA (PSEUDO-SYMMETRIC MONOMER) 分子名称: CYCLOPHILIN A, PEPTIDE FROM THE HIV-1 CAPSID PROTEIN 著者 Vajdos, F.F. 登録日 1997-10-05 公開日 1998-03-18 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein. Protein Sci., 6, 1997
3I8C	Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A 分子名称: DNA damage-binding protein 1, WD repeat-containing protein 21A 著者 Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. 登録日 2009-07-09 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010

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