PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

---

2WKY	Crystal structure of the ligand-binding core of GluR5 in complex with the agonist 4-AHCP 分子名称: 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... 著者 Naur, P, Gajhede, M, Kastrup, J.S. 登録日 2009-06-18 公開日 2009-07-21 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Glutamate Receptor Glur5 Agonist (S)-2-Amino-3-(3-Hydroxy-7,8-Dihydro-6H-Cyclohepta[D]Isoxazol-4-Yl)Propionic Acid and the 8-Methyl Analogue: Synthesis, Molecular Pharmacology, and Biostructural Characterization J.Med.Chem., 52, 2009
4LB3	Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(2-fluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 著者 Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. 登録日 2013-06-20 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
8B97	N-terminal beta-trefoil lectin domain of the Laccaria bicolor lectin in complex with N-acetyl-lactosamine 分子名称: Beta-trefoil domain of the LBL lectin, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Acebron, I, Campanero-Rhodes, M.A, Solis, D, Menendez, M, Garcia, C, Lillo, M.P, Mancheno, J.M. 登録日 2022-10-05 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Atomic crystal structure and sugar specificity of a beta-trefoil lectin domain from the ectomycorrhizal basidiomycete Laccaria bicolor. Int.J.Biol.Macromol., 233, 2023
8BDW	Crystal structure of CnaB2 domain from Lactobacillus plantarum 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell surface adherence protein,collagen-binding domain, LPXTG-motif cell wall anchor, ... 著者 Taberman, H, Hakanpaa, J, Linder, M.B, Aranko, A.S. 登録日 2022-10-20 公開日 2023-02-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Biomolecular Click Reactions Using a Minimal pH-Activated Catcher/Tag Pair for Producing Native-Sized Spider-Silk Proteins. Angew.Chem.Int.Ed.Engl., 62, 2023
3P6D	Human adipocyte lipid-binding protein FABP4 in complex with 3-(4-methoxy-3-methylphenyl) propionic acid 分子名称: 3-(4-methoxy-3-methylphenyl)propanoic acid, Fatty acid-binding protein, adipocyte 著者 Gonzalez, J.M, Pozharski, E. 登録日 2010-10-11 公開日 2011-04-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4). Acta Crystallogr F Struct Biol Commun, 71, 2015
4KUW	Crystal structure of human carbonic anhydrase II in complex with the 5-(3-(4-fluorophenylsulfonyl)ureido)pyridine-2-sulfonamide inhibitor 分子名称: 5-({[(4-fluorophenyl)sulfonyl]carbamoyl}amino)pyridine-2-sulfonamide, BETA-MERCAPTOETHANOL, Carbonic anhydrase 2, ... 著者 Ferraroni, M. 登録日 2013-05-22 公開日 2014-06-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 New classes of carbonic anhydrase inhibitors to be published
1GB1	A NOVEL, HIGHLY STABLE FOLD OF THE IMMUNOGLOBULIN BINDING DOMAIN OF STREPTOCOCCAL PROTEIN G 分子名称: PROTEIN G 著者 Gronenborn, A.M, Clore, G.M. 登録日 1991-05-15 公開日 1993-04-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A novel, highly stable fold of the immunoglobulin binding domain of streptococcal protein G. Science, 253, 1991
8BT1	YdaT transcription regulator (CII functional analog) 分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ... 著者 Prolic-Kalinsek, M, Loris, R. 登録日 2022-11-27 公開日 2023-02-22 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.39788437 Å) 主引用文献 Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7. Acta Crystallogr D Struct Biol, 79, 2023
6YO4	Para-Carborane propyl-sulfonamide in complex with CA IX mimic 分子名称: Carbonic anhydrase 2, Para-Carborane propyl-sulfonamide, ZINC ION 著者 Kugler, M, Brynda, J, Pospisilova, K, Rezacova, P. 登録日 2020-04-14 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme. Chemistry, 26, 2020
5CDH	Structure of Legionella pneumophila Histidine Acid Phosphatase complexed with L(+)-tartrate 分子名称: L(+)-TARTARIC ACID, Major acid phosphatase, PENTAETHYLENE GLYCOL 著者 Tanner, J.J. 登録日 2015-07-04 公開日 2016-01-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Crystal structure and tartrate inhibition of Legionella pneumophila histidine acid phosphatase. Arch.Biochem.Biophys., 585, 2015
6YOK	Para-Carborane di-propyl-sulfonamide in complex with CA IX mimic 分子名称: Carbonic anhydrase 2, Para-Carborane di-propyl-sulfonamide, ZINC ION 著者 Kugler, M, Brynda, J, Pospisilova, K, Rezacova, P. 登録日 2020-04-14 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme. Chemistry, 26, 2020
8BNV	Crystal structure of Pif1 from Deferribacter desulfuricans in apo from 分子名称: AAA family ATPase, GLYCEROL, MAGNESIUM ION 著者 Rety, S, Chen, W.F, Xi, X.G. 登録日 2022-11-14 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural Studies of Pif1 Helicases from Thermophilic Bacteria. Microorganisms, 11, 2023
8BOG	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 7 分子名称: Ephrin type-A receptor 2, ~{N}-[4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]phenyl]-3-(trifluoromethyl)benzamide 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BDN	VCB in complex with compound 23 分子名称: (2~{R})-3-methyl-1-[(2~{S},4~{R})-2-[(5~{R})-5-methyl-5-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-4~{H}-1,2,4-oxadiazol-3-yl]-4-oxidanyl-pyrrolidin-1-yl]-2-(3-methyl-1,2-oxazol-5-yl)butan-1-one, Elongin-B, Elongin-C, ... 著者 Sorrell, F.J, Mueller, J.E, Lehmann, M, Wegener, A. 登録日 2022-10-19 公開日 2023-02-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design. Chemmedchem, 18, 2023
2BO7	DISSECTION OF MANNOSYLGLYCERATE SYNTHASE: AN ARCHETYPAL MANNOSYLTRANSFERASE 分子名称: COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, MANNOSYLGLYCERATE SYNTHASE 著者 Flint, J, Taylor, E, Yang, M, Bolam, D.N, Tailford, L.E, Martinez-Fleites, C, Dodson, E.J, Davis, B.G, Gilbert, H.J, Davies, G.J. 登録日 2005-04-08 公開日 2005-06-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural dissection and high-throughput screening of mannosylglycerate synthase. Nat. Struct. Mol. Biol., 12, 2005
5CGZ	Crystal structure of GalB, the 4-carboxy-2-hydroxymuconate hydratase, from Pseuodomonas putida KT2440 分子名称: 4-oxalmesaconate hydratase, GLYCEROL, ZINC ION 著者 Mazurkewich, S, Brott, A.S, Kimber, M.S, Seah, S.Y.K. 登録日 2015-07-09 公開日 2016-02-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440. J.Biol.Chem., 291, 2016
4ANJ	MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ... 著者 Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M. 登録日 2012-03-19 公開日 2012-10-17 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi. Mol.Cell, 48, 2012
8BHE	K141H and S142H double mutant of hGSTA1-1 分子名称: Glutathione S-transferase A1 著者 Papageorgiou, A.C, Poudel, N. 登録日 2022-10-31 公開日 2023-03-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1. Int J Mol Sci, 24, 2023
6YEI	Arabidopsis thaliana glutamate dehydrogenase isoform 1 in complex with NAD 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... 著者 Ruszkowski, M, Grzechowiak, M, Jaskolski, M. 登録日 2020-03-24 公開日 2020-05-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural Studies of Glutamate Dehydrogenase (Isoform 1) FromArabidopsis thaliana, an Important Enzyme at the Branch-Point Between Carbon and Nitrogen Metabolism. Front Plant Sci, 11, 2020
6YLG	Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement) 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Kater, L, Beckmann, R. 登録日 2020-04-07 公開日 2020-07-29 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
8BHC	K141H and S142H double mutant of hGSTA1-1 分子名称: Glutathione S-transferase A1 著者 Papageorgiou, A.C, Poudel, N. 登録日 2022-10-31 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 A Key Role in Catalysis and Enzyme Thermostability of a Conserved Helix H5 Motif of Human Glutathione Transferase A1-1. Int J Mol Sci, 24, 2023
4IWK	Crystal structure of iron soaked (overnight) ferritin from Pseudo-nitzschia multiseries 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2013-01-23 公開日 2013-03-20 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Mechanism of ferrous iron binding and oxidation by ferritin from a pennate diatom. J.Biol.Chem., 288, 2013
6C7W	Carbonic anhydrase 2 in complex with [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE inhibitor 分子名称: Carbonic anhydrase 2, SODIUM ION, ZINC ION, ... 著者 Peat, T.S, Mujumdar, P, Poulsen, S.A. 登録日 2018-01-23 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Synthesis, structure and bioactivity of primary sulfamate-containing natural products. Bioorg. Med. Chem. Lett., 28, 2018
8BFF	Human PPARgamma in complex with MINCH bound to the AF-2 sub-pocket 分子名称: (1~{S},2~{R})-2-[(4~{R})-4-methylheptoxy]carbonylcyclohexane-1-carboxylic acid, Peroxisome proliferator-activated receptor gamma 著者 Useini, A, Straeter, N. 登録日 2022-10-25 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of the activation of PPAR gamma by the plasticizer metabolites MEHP and MINCH. Environ Int, 173, 2023
3OIK	Human Carbonic anhydrase II mutant A65S, N67Q (CA IX mimic) bound by 2-Ethylestradiol 3,17-O,O-bis-sulfamate 分子名称: (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, Carbonic anhydrase 2, GLYCEROL, ... 著者 Sippel, K.H, Stander, B.A, Robbins, A.H, Tu, C.K, Agbandje-McKenna, M, Silverman, D.N, Joubert, A.M, McKenna, R. 登録日 2010-08-19 公開日 2011-07-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8, 2011

<900901902903904905906907908909910911912913914915>