6Y11
| Respiratory complex I from Thermus thermophilus | 分子名称: | DUF3197 domain-containing protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | 登録日 | 2020-02-10 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.109 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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3IAS
| Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 4 mol/ASU, re-refined to 3.15 angstrom resolution | 分子名称: | CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Sazanov, L.A, Berrisford, J.M. | 登録日 | 2009-07-14 | 公開日 | 2009-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural basis for the mechanism of respiratory complex I J.Biol.Chem., 284, 2009
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7AK5
| Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | 登録日 | 2020-09-29 | 公開日 | 2021-02-03 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Structural basis for a complex I mutation that blocks pathological ROS production. Nat Commun, 12, 2021
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6RFR
| Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | 著者 | Parey, K, Vonck, J. | 登録日 | 2019-04-16 | 公開日 | 2019-12-11 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Sci Adv, 5, 2019
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1OGY
| Crystal structure of the heterodimeric nitrate reductase from Rhodobacter sphaeroides | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DIHEME CYTOCHROME C NAPB MOLECULE: NITRATE REDUCTASE, HEME C, ... | 著者 | Arnoux, P, Sabaty, M, Alric, J, Frangioni, B, Guigliarelli, B, Adriano, J.-M, Pignol, D. | 登録日 | 2003-05-19 | 公開日 | 2003-10-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and Redox Plasticity in the Heterodimeric Periplasmic Nitrate Reductase Nat.Struct.Biol., 10, 2003
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8CA3
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2). | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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7V32
| Deactive state complex I from rotenone dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-08-10 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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8OH9
| Cryo-EM structure of the electron bifurcating transhydrogenase StnABC complex from Sporomusa Ovata (state 1) | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, Formate dehydrogenase-O, ... | 著者 | Kumar, A, Kremp, F, Mueller, V, Schuller, J.M. | 登録日 | 2023-03-20 | 公開日 | 2023-09-13 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Molecular architecture and electron transfer pathway of the Stn family transhydrogenase. Nat Commun, 14, 2023
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8E73
| Vigna radiata supercomplex I+III2 (full bridge) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | 著者 | Maldonado, M, Letts, J.A. | 登録日 | 2022-08-23 | 公開日 | 2023-01-11 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Plant-specific features of respiratory supercomplex I + III 2 from Vigna radiata. Nat.Plants, 9, 2023
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7P61
| Complex I from E. coli, DDM-purified, with NADH, Resting state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-15 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7M
| Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7VZV
| Active state CI from Q10 dataset, Subclass 1 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-16 | 公開日 | 2022-12-14 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7VZW
| Active state CI from Q10 dataset, Subclass 2 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-16 | 公開日 | 2022-12-14 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7W1U
| Active state CI from Rotenone dataset, Subclass 2 | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-20 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6Y79
| Cryo-EM structure of a respiratory complex I F89A mutant | 分子名称: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | 著者 | Parey, K. | 登録日 | 2020-02-28 | 公開日 | 2020-10-28 | 最終更新日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Essential role of accessory subunit LYRM6 in the mechanism of mitochondrial complex I. Nat Commun, 11, 2020
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7T2R
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7W4J
| Deactive state CI from Q1-NADH dataset, Subclass 1 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-28 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7W4K
| Deactive state CI from Q1-NADH dataset, Subclass 2 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-28 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6I1P
| Respiratory complex I from Thermus thermophilus with bound NADH | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | 登録日 | 2018-10-29 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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6TG9
| Cryo-EM Structure of NADH reduced form of NAD+-dependent Formate Dehydrogenase from Rhodobacter capsulatus | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wendler, P, Radon, C, Mittelstaedt, G. | 登録日 | 2019-11-15 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase. Nat Commun, 11, 2020
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8CA4
| Cryo-EM structure NDUFS4 knockout complex I from Mus musculus heart (Class 2 N-domain). | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | 著者 | Yin, Z, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-01-24 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4 -/- mouse. Embo J., 43, 2024
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6TGA
| Cryo-EM Structure of as isolated form of NAD+-dependent Formate Dehydrogenase from Rhodobacter capsulatus | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Wendler, P, Radon, C, Mittelstaedt, G. | 登録日 | 2019-11-15 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase. Nat Commun, 11, 2020
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8B9Z
| Drosophila melanogaster complex I in the Active state (Dm1) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | 登録日 | 2022-10-10 | 公開日 | 2023-01-18 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster. Elife, 12, 2023
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6G2J
| Mouse mitochondrial complex I in the active state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J. | 登録日 | 2018-03-23 | 公開日 | 2018-06-06 | 最終更新日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states. Nat. Struct. Mol. Biol., 25, 2018
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7NYR
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