PDB: 278 件ウェブページステータス検索Chemie searchBIRD

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4EZO	Crystal structure of the substrate binding domain of E.coli DnaK in complex with PR-39 (residues 1 to 15) 分子名称: Antibacterial protein PR-39, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZZ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide ELPLVKI 分子名称: Chaperone protein DnaK, synthetic peptide ELPLVKI 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZQ	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of pyrrhocoricin (residues 12 to 20) 分子名称: Chaperone protein DnaK, Pyrrhocoricin 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZS	Crystal structure of the substrate binding domain of E.coli DnaK in complex with metchnikowin (residues 20 to 26) 分子名称: Chaperone protein DnaK, Metchnikowin, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural studies of DnaK in complex with proline rich antimicrobial peptides reveal two different peptide binding modes To be Published
4EZY	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLILTG 分子名称: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLILTG 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZN	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin 分子名称: Chaperone protein DnaK, Pyrrhocoricin 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4EZX	Crystal structure of the substrate binding domain of E.coli DnaK in complex with the designer peptide NRLMLTG 分子名称: Chaperone protein DnaK, SULFATE ION, synthetic peptide NRLMLTG 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
5BPN	Crystal structure of nucleotide-free human Hsp70 NBD double mutant E268Q+R272K. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heat shock 70 kDa protein 1A, ... 著者 Narayanan, D, Engh, R.A. 登録日 2015-05-28 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BN8	Crystal structure of nucleotide-free human Hsp70 NBD. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Heat shock 70 kDa protein 1A, ... 著者 Narayanan, D, Engh, R.A. 登録日 2015-05-25 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Nucleotide binding to variants of the HSP70-NBD. To Be Published
5BN9	Crystal structure of ADP bound human Hsp70 NBD mutant R272K. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Narayanan, D, Engh, R.A. 登録日 2015-05-25 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.689 Å) 主引用文献 Nucleotide binding to variants of the HSP70-NBD. To Be Published
5E86	isolated SBD of BiP with loop34 modification 分子名称: 78 kDa glucose-regulated protein 著者 Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. 登録日 2015-10-13 公開日 2015-12-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.681 Å) 主引用文献 Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
5E84	ATP-bound state of BiP 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. 登録日 2015-10-13 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
5E85	isolated SBD of BiP 分子名称: 78 kDa glucose-regulated protein, SULFATE ION 著者 Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. 登録日 2015-10-13 公開日 2015-12-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
5AQZ	HSP72 with adenosine-derived inhibitor 分子名称: 1,2-ETHANEDIOL, HEAT SHOCK 70 KDA PROTEIN 1A, SANGIVAMYCIN 著者 Cheeseman, M.D, Westwood, I.M, Barbeau, O, Rowlands, M.G, Jones, A.M, Jeganathan, F, Burke, R, Dobson, S.E, Workman, P, Collins, I, van Montfort, R.L.M, Jones, K. 登録日 2015-09-22 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of Hsp70. J.Med.Chem., 59, 2016
5AQW	Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues 分子名称: (1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol, (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2-ETHANEDIOL, ... 著者 Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. 登録日 2015-09-22 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
5AR0	HSP72 with adenosine-derived inhibitor 分子名称: (2R,3R,4S,5R)-2-(6-amino-8-((quinolin-7-ylmethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Cheeseman, M.D, Westwood, I.M, Barbeau, O, Rowlands, M.G, Jones, A.M, Jeganathan, F, Burke, R, Dobson, S.E, Workman, P, Collins, I, van Montfort, R.L.M, Jones, K. 登録日 2015-09-22 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of Hsp70. J.Med.Chem., 59, 2016
5EVZ	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ADP and inorganic phosphate 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-20 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5F2R	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with AMP-PCP 分子名称: 78 kDa glucose-regulated protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-12-02 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5EXW	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ATP 分子名称: 7-deazaadenosine-5'-triphosphate, 78 kDa glucose-regulated protein 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-24 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5F1X	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ATP 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-30 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5EY4	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 2'-deoxy-ATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 78 kDa glucose-regulated protein 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-24 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5F0X	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 2'-deoxy-ADP and inorganic phosphate 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, 78 kDa glucose-regulated protein, ... 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-28 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
5EX5	Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ADP and inorganic phosphate 分子名称: 7-deazaadenosine-5'-diphosphate, 78 kDa glucose-regulated protein, MAGNESIUM ION, ... 著者 Hughes, S.J, Antoshchenko, T, Song, J.H, Pizarro, J, Park, H.W. 登録日 2015-11-23 公開日 2016-06-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. Plos One, 11, 2016
7SQC	Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii 分子名称: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ... 著者 Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R. 登録日 2021-11-05 公開日 2022-04-13 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ciliary central apparatus structure reveals mechanisms of microtubule patterning. Nat.Struct.Mol.Biol., 29, 2022
7X3K	Cryo-EM structure of RAC in the State C2 RNC-RAC complex 分子名称: Ribosome-associated complex subunit SSZ1, Zuotin 著者 Chen, Y, Gao, N. 登録日 2022-03-01 公開日 2022-06-29 実験手法 ELECTRON MICROSCOPY (6 Å) 主引用文献 Structural remodeling of ribosome associated Hsp40-Hsp70 chaperones during co-translational folding. Nat Commun, 13, 2022

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