PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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7OSW	Structure and folding of a 600-million-year-old nuclear coactivator binding domain suggest conservation of dynamic properties 分子名称: NCBD 著者 Chi, C. 登録日 2021-06-09 公開日 2022-04-20 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The dynamic properties of a nuclear coactivator binding domain are evolutionarily conserved. Commun Biol, 5, 2022
7PEQ	Model of the outer rings of the human nuclear pore complex 分子名称: Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ... 著者 Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. 登録日 2021-08-11 公開日 2021-10-20 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 The cellular environment shapes the nuclear pore complex architecture. Nature, 598, 2021
7Q4O	Substrate-bound A-like U2 snRNP 分子名称: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... 著者 Tholen, J, Galej, W.P. 登録日 2021-11-01 公開日 2022-03-30 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q4P	U2 snRNP after ATP-dependent remodelling 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, Splicing factor 3A subunit 3, ... 著者 Tholen, J, Galej, W.P. 登録日 2021-11-01 公開日 2022-03-30 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
6SZS	Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Muller, C, Beckert, B, Wilson, D.N. 登録日 2019-10-02 公開日 2019-12-04 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis. Nat Commun, 10, 2019
6BY1	E. coli pH03H9 complex 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Amiri, H, Noller, H.F. 登録日 2017-12-19 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 Structural evidence for product stabilization by the ribosomal mRNA helicase. Rna, 25, 2019
7S1K	Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Tsai, K, Stojkovic, V, Lee, D.J, Young, I.D, Szal, T, Vazquez-Laslop, N, Mankin, A.S, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2022-01-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
7SSW	Late translocation intermediate with EF-G dissociated (Structure VI) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SSN	Pre translocation 70S ribosome with A/P* and P/E tRNA (Structure II-B) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SS9	Late translocation intermediate with EF-G partially dissociated (Structure V) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Loveland, A.B, Gamper, H.B, Hou, Y, Korostelev, A.A. 登録日 2021-11-10 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST7	Pre translocation intermediate stalled with viomycin and bound with EF-G in a GDP and Pi state (Structure III-vio) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-12 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST6	Pre translocation, non-rotated 70S ribosome (Structure I) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-12 公開日 2022-02-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SSL	Pre translocation intermediate with EF-G bound to GDP and Pi (Structure III) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7ST2	Post translocation, non-rotated 70S ribosome with EF-G dissociated (Structure VII) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7QCD	CryoEM structure of the Smc5/6-holocomplex (composite structure) 分子名称: E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosome element 4, ... 著者 Hallett, S.T, Oliver, A.W. 登録日 2021-11-23 公開日 2022-09-21 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Cryo-EM structure of the Smc5/6 holo-complex. Nucleic Acids Res., 50, 2022
7S1I	Wild-type Escherichia coli stalled ribosome with antibiotic radezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2022-03-02 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
7S1J	Wild-type Escherichia coli ribosome with antibiotic radezolid 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. 登録日 2021-09-02 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
8PVA	Structure of bacterial ribosome determined by cryoEM at 100 keV 分子名称: 16S rRNA, 23S rRNA, 50S ribosomal protein L14, ... 著者 McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. 登録日 2023-07-17 公開日 2023-11-29 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
7SSO	Pre translocation 70S ribosome with A/A and P/E tRNA (Structure II-A) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-11 公開日 2022-02-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
7SSD	Mid translocation intermediate with EF-G bound with GDP (Structure IV) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Carbone, C.E, Korostelev, A.A. 登録日 2021-11-10 公開日 2022-02-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP. Nat Commun, 12, 2021
8PHJ	cA4-bound Cami1 in complex with 70S ribosome 分子名称: 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ... 著者 Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G. 登録日 2023-06-20 公開日 2023-12-13 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling. Science, 382, 2023
6TE1	Structure of the KDM1A/CoREST complex with the inhibitor 2-[3-{4-chloro-3-[(4-chlorophenyl)ethynyl]phenyl}-1-(3-morpholin-4-ylpropyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-2-oxoethanol 分子名称: 5-[4-cyclobutyl-1-[2-(4-piperidin-4-yloxyphenoxy)ethyl]imidazol-2-yl]-4-methyl-thieno[3,2-b]pyrrole, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Pasqualato, S, Cecatiello, V. 登録日 2019-11-11 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models. Acs Med.Chem.Lett., 11, 2020
8P18	E167K RF2 on E. coli 70S release complex with UGG (Structure III) 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. 登録日 2023-05-11 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria To Be Published
8P16	E167K RF2 on E. coli 70S release complex with UGG (Structure I) 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. 登録日 2023-05-11 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria To Be Published
8P17	E167K RF2 on E. coli 70S release complex with UGG (Structure II) 分子名称: 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ... 著者 Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. 登録日 2023-05-11 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.78 Å) 主引用文献 The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria To Be Published

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