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1SNT
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Structure of the human cytosolic sialidase Neu2
分子名称: Sialidase 2
著者Chavas, L.M.G, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Kato, R, Monti, E, Wakatsuki, S.
登録日2004-03-12
公開日2004-11-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
1EGC
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BU of 1egc by Molmil
STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A
著者Lee, H.J, Wang, M, Paschke, R, Nandy, A, Ghisla, S, Kim, J.P.
登録日1996-04-11
公開日1997-11-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1ELX
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BU of 1elx by Molmil
E. COLI ALKALINE PHOSPHATASE MUTANT (S102A)
分子名称: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R.
登録日1998-02-10
公開日1998-05-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
J.Mol.Biol., 277, 1998
4XJD
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BU of 4xjd by Molmil
X-ray structure of Lysozyme2
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-08
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
4XJH
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BU of 4xjh by Molmil
X-ray structure of LysozymeS1
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Huang, C.Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M.
登録日2015-01-08
公開日2015-06-03
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献In meso in situ serial X-ray crystallography of soluble and membrane proteins.
Acta Crystallogr.,Sect.D, 71, 2015
4K8D
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BU of 4k8d by Molmil
Crystal structure of the C558(464)A/C559(465)A double mutant of Tn501 MerA in complex with NADPH and Hg2+
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Mercuric reductase, ...
著者Dong, A, Falkowski, M, Malone, M, Miller, S.M, Pai, E.F.
登録日2013-04-18
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structure of the C136(42)A/C141(47)A double mutant of Tn501 MerA in complex with NADPH and Hg2+
to be published
3M1L
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BU of 3m1l by Molmil
Crystal structure of a C-terminal trunacted mutant of a putative ketoacyl reductase (FabG4) from Mycobacterium tuberculosis H37Rv at 2.5 Angstrom resolution
分子名称: 3-oxoacyl-(Acyl-carrier-protein) reductase, ACETATE ION
著者Dutta, D, Bhattacharyya, S, Saha, B, Das, A.K.
登録日2010-03-05
公開日2010-12-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Crystal structure of FabG4 from Mycobacterium tuberculosis reveals the importance of C-terminal residues in ketoreductase activity
J.Struct.Biol., 174, 2011
5HMJ
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Re-refinement of 4xan: hen lysozyme with carboplatin in sodium bromide solution
分子名称: ACETATE ION, BROMIDE ION, DIMETHYL SULFOXIDE, ...
著者Helliwell, J.R.
登録日2016-01-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.299901 Å)
主引用文献Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.
Acta Crystallogr F Struct Biol Commun, 72, 2016
1S74
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BU of 1s74 by Molmil
SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN ALPHA-ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE RECOGNITION BY ENDONUCLEASE IV
分子名称: 5'-D(*CP*GP*TP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*(A3A)P*CP*GP*AP*CP*G)-3'
著者Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W.
登録日2004-01-28
公開日2004-04-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
4KBZ
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BU of 4kbz by Molmil
Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) with (S)-{2-[2-(5-Cyano-3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetylamino}-phenyl-acetic acid
分子名称: (2S)-({[2-(5-cyano-3-hydroxypyridin-2-yl)-1,3-thiazol-4-yl]acetyl}amino)(phenyl)ethanoic acid, Egl nine homolog 1, FE (II) ION, ...
著者Kim, H.T, Hong, Y.R, Chang, H.J.
登録日2013-04-24
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献

5HN3
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BU of 5hn3 by Molmil
Crystal structure of beta-decarboxylating dehydrogenase (TK0280) from Thermococcus kodakarensis (apo form)
分子名称: Homoisocitrate dehydrogenase, IMIDAZOLE, SODIUM ION
著者Shimizu, T, Tomita, T, Nishiyama, M.
登録日2016-01-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and function of an ancestral-type beta-decarboxylating dehydrogenase from Thermococcus kodakarensis
Biochem. J., 474, 2017
4KEV
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BU of 4kev by Molmil
Crystal structure of SsoPox W263L
分子名称: Aryldialkylphosphatase, COBALT (II) ION, FE (II) ION
著者Gotthard, G, Hiblot, J, Chabriere, E, Elias, M.
登録日2013-04-26
公開日2013-10-02
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox.
Plos One, 8, 2013
5HP4
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BU of 5hp4 by Molmil
Crystal structure bacteriohage T5 D15 flap endonuclease (D155K) pseudo-enzyme-product complex with DNA and metal ions
分子名称: CALCIUM ION, DNA (5'-D(*GP*AP*TP*CP*TP*AP*TP*AP*TP*GP*CP*CP*AP*TP*CP*GP*G)-3'), Exodeoxyribonuclease, ...
著者Almalki, F.A, Zhang, J, Sedelnikova, S.E, Rafferty, J.B, Sayers, J.R, Artymiuk, P.A.
登録日2016-01-20
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Direct observation of DNA threading in flap endonuclease complexes.
Nat.Struct.Mol.Biol., 23, 2016
5HVN
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BU of 5hvn by Molmil
3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with NAD.
分子名称: 3-dehydroquinate synthase, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Minasov, G, Light, S.H, Shuvalova, L, Dubrovska, I, Winsor, J, Zhou, M, Grimshaw, S, Kwon, K, Joachimiak, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-01-28
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with NAD.
To Be Published
7D6J
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BU of 7d6j by Molmil
Human serum albumin complexed with benzbromarone
分子名称: Serum albumin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone
著者Kawai, A, Yamasaki, K.
登録日2020-09-30
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions.
Mol Pharm., 18, 2021
1EUH
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BU of 1euh by Molmil
APO FORM OF A NADP DEPENDENT ALDEHYDE DEHYDROGENASE FROM STREPTOCOCCUS MUTANS
分子名称: NADP DEPENDENT NON PHOSPHORYLATING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, SULFATE ION
著者Cobessi, D, Tete-Favier, F, Marchal, S, Branlant, G, Aubry, A.
登録日1998-11-05
公開日1999-07-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Apo and holo crystal structures of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans.
J.Mol.Biol., 290, 1999
4XAQ
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BU of 4xaq by Molmil
mGluR2 ECD and mGluR3 ECD with ligands
分子名称: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, CHLORIDE ION, Metabotropic glutamate receptor 2, ...
著者Clawson, D.K.
登録日2014-12-15
公開日2015-02-04
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures.
J.Med.Chem., 58, 2015
5HXM
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BU of 5hxm by Molmil
Cycloalternan-forming enzyme from Listeria monocytogenes in complex with panose
分子名称: Alpha-xylosidase, CALCIUM ION, CHLORIDE ION, ...
著者Halavaty, A.S, Light, S.H, Minasov, G, Winsor, J, Grimshaw, S, Shuvalova, L, Peterson, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-01-31
公開日2017-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.
Structure, 25, 2017
4XGV
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BU of 4xgv by Molmil
Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V.
登録日2015-01-02
公開日2015-12-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.883 Å)
主引用文献Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm.
Microbiologyopen, 5, 2016
4XB3
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BU of 4xb3 by Molmil
Structure of dextran glucosidase
分子名称: CALCIUM ION, Glucan 1,6-alpha-glucosidase, HEXAETHYLENE GLYCOL
著者Kobayashi, M, Kato, K, Yao, M.
登録日2014-12-16
公開日2015-08-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Structural insights into the catalytic reaction that is involved in the reorientation of Trp238 at the substrate-binding site in GH13 dextran glucosidase
Febs Lett., 589, 2015
3MV6
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BU of 3mv6 by Molmil
Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
分子名称: 3,4-DIHYDROXYBENZOIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Purpero, V.M, Lipscomb, J.D.
登録日2010-05-03
公開日2011-06-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
To be Published
3MVK
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BU of 3mvk by Molmil
The Crystal Structure of FucU from Bifidobacterium longum to 1.65A
分子名称: GLYCEROL, SODIUM ION, TRIETHYLENE GLYCOL, ...
著者Stein, A.J, Xu, X, Cui, H, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2010-05-04
公開日2010-05-12
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Crystal Structure of FucU from Bifidobacterium longum to 1.65A
To be Published
1SIQ
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BU of 1siq by Molmil
The Crystal Structure and Mechanism of Human Glutaryl-CoA Dehydrogenase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glutaryl-CoA dehydrogenase
著者Wang, M, Fu, Z, Paschke, R, Goodman, S, Frerman, F.E, Kim, J.J.
登録日2004-03-01
公開日2004-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
4XHY
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BU of 4xhy by Molmil
NADH:FMN oxidoreductase from Paracoccus denitrificans
分子名称: Flavin reductase domain protein, FMN-binding protein
著者Sedlacek, V, Klumpler, T, Marek, J, Kucera, I.
登録日2015-01-06
公開日2016-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Biochemical properties and crystal structure of the flavin reductase FerA from Paracoccus denitrificans.
Microbiol. Res., 188-189, 2016
4KGX
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The R state structure of E. coli ATCase with CTP bound
分子名称: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R.
登録日2013-04-29
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013

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