PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

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5VC5	Crystal structure of human WEE1 kinase domain in complex with PD-166285 分子名称: 1,2-ETHANEDIOL, 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, ... 著者 Zhu, J.-Y, Schonbrunn, E. 登録日 2017-03-31 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
5VMC	Influenza hemagglutinin H1 mutant DH1 in complex with 6'SLN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... 著者 Ni, F, Kondrashkina, E, Wang, Q. 登録日 2017-04-27 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Determinant of receptor-preference switch in influenza hemagglutinin. Virology, 513, 2017
1UM4	Catalytic Antibody 21H3 with hapten 分子名称: (1R)-1-PHENYLETHYL 4-(ACETYLAMINO)BENZYLPHOSPHONATE, Antibody 21H3 H chain, Antibody 21H3 L chain 著者 Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. 登録日 2003-09-23 公開日 2004-10-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms To be Published
4MEX	Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2014-06-25 実験手法 X-RAY DIFFRACTION (3.902 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
7M1V	Structure of Zika virus NS2b-NS3 protease mutant binding the compound NSC86314 in the super-open conformation 分子名称: 1,2-ETHANEDIOL, 4-(2-{2,4-diamino-5-[2-(4-{[(2E)-1,3-thiazolidin-2-ylidene]sulfamoyl}phenyl)hydrazinyl]phenyl}hydrazinyl)-N-[(2S)-1,3-thiazolidin-2-yl]benzene-1-sulfonamide, CHLORIDE ION, ... 著者 Aleshin, A.E, Shiryaev, S.A, Liddington, R.C. 登録日 2021-03-15 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 To be provided To Be Published
2G0A	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(II) bound in active site 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III, LEAD (II) ION 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
5MR8	Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K9ac histone peptide 分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3, ZINC ION 著者 Tallant, C, Savitsky, P, Fedorov, O, Nunez-Alonso, G, Siejka, P, Krojer, T, Williams, E, Srikannathasan, V, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2016-12-21 公開日 2018-01-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K9ac histone peptide To Be Published
5MXK	Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7G9. 分子名称: 1,2-ETHANEDIOL, HTH-type transcriptional regulator EthR, ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide 著者 Mendes, V, Chan, D.S.-H, Thomas, S.E, McConnell, B, Matak-Vinkovic, D, Coyne, A.G, Abell, C, Blundell, T.L. 登録日 2017-01-23 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.932 Å) 主引用文献 Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry. Angew. Chem. Int. Ed. Engl., 56, 2017
6CUJ	Crystal structure of the C-terminal domain of neisserial heparin binding antigen (NHBA) 分子名称: Gna2132 著者 Malito, E, Spraggon, G. 登録日 2018-03-26 公開日 2018-09-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.805 Å) 主引用文献 Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody. PLoS ONE, 13, 2018
2BBA	Crystal Structure and Thermodynamic Characterization of the EphB4 Receptor in Complex with an ephrin-B2 Antagonist Peptide Reveals the Determinants for Receptor Specificity. 分子名称: Agonist peptide, Ephrin type-B receptor 4, SULFATE ION 著者 Chrencik, J.E, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) 登録日 2005-10-17 公開日 2006-07-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity. Structure, 14, 2006
1UXQ	Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax 分子名称: 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Lorentzen, E, Hensel, R, Pohl, E. 登録日 2004-03-01 公開日 2004-08-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
5MTT	Maltodextrin binding protein MalE1 from L. casei BL23 bound to maltotetraose 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MalE1, ... 著者 Homburg, C, Bommer, M, Wuttge, S, Hobe, C, Beck, S, Dobbek, H, Deutscher, J, Licht, A, Schneider, E. 登録日 2017-01-10 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Inducer exclusion in Firmicutes: insights into the regulation of a carbohydrate ATP binding cassette transporter from Lactobacillus casei BL23 by the signal transducing protein P-Ser46-HPr. Mol. Microbiol., 105, 2017
5MU4	Tail Tubular Protein A of Klebsiella pneumoniae bacteriophage KP32 分子名称: Tail tubular protein A 著者 Pyra, A, Brzozowska, E, Pawlik, K, Dauter, M, Dauter, Z, Gamian, A. 登録日 2017-01-12 公開日 2017-05-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Tail tubular protein A: a dual-function tail protein of Klebsiella pneumoniae bacteriophage KP32. Sci Rep, 7, 2017
2FZS	Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site 分子名称: ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE, ... 著者 Szyk, A, Maurizi, M.R. 登録日 2006-02-10 公開日 2006-05-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site. J.Struct.Biol., 156, 2006
4N7I	Crystal Structure of Intracellular B30.2 Domain of BTN3A1 分子名称: BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, CHLORIDE ION, ... 著者 Sandstrom, A, Adams, E.J. 登録日 2013-10-15 公開日 2014-04-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4015 Å) 主引用文献 The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human V gamma 9V delta 2 T Cells. Immunity, 40, 2014
6CMN	Co-Crystal Structure of HIV-1 TAR Bound to Lab-Evolved RRM TBP6.7 分子名称: TAR-Binding Protein 6.7, Trans-Activation Response RNA Element 著者 Belashov, I.A, Wedekind, J.E. 登録日 2018-03-05 公開日 2018-06-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Structure of HIV TAR in complex with a Lab-Evolved RRM provides insight into duplex RNA recognition and synthesis of a constrained peptide that impairs transcription. Nucleic Acids Res., 46, 2018
1ZNX	Crystal Structure Of Mycobacterium tuberculosis Guanylate Kinase In Complex With GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase 著者 Hible, G, Christova, P, Renault, L, Seclaman, E, Thompson, A, Girard, E, Munier-Lehmann, H, Cherfils, J. 登録日 2005-05-12 公開日 2005-11-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Unique GMP-binding site in Mycobacterium tuberculosis guanosine monophosphate kinase Proteins, 62, 2006
1OSD	crystal structure of Oxidized MerP from Ralstonia metallidurans CH34 分子名称: hypothetical protein MerP 著者 Serre, L, Rossy, E, Pebay-Peyroula, E, Cohen-Addad, C, Coves, J. 登録日 2003-03-19 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Oxidized Form of the Periplasmic Mercury-binding Protein MerP from Ralstonia metallidurans CH34 J.MOL.BIOL., 339, 2004
5V5Y	CRYSTAL STRUCTURE OF HUMAN WEE1 KINASE DOMAIN IN COMPLEX WITH MK1775 分子名称: 1,2-ETHANEDIOL, 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, DIMETHYL SULFOXIDE, ... 著者 ZHU, J.-Y, SCHONBRUNN, E. 登録日 2017-03-15 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017
5LA3	[FeFe]-hydrogenase CpI from Clostridium pasteurianum, variant E279A 分子名称: FE2/S2 (INORGANIC) CLUSTER, IRON/SULFUR CLUSTER, Iron hydrogenase 1, ... 著者 Duan, J, Esselborn, J, Hofmann, E, Winkler, M, Happe, T. 登録日 2016-06-13 公開日 2017-06-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Accumulating the hydride state in the catalytic cycle of [FeFe]-hydrogenases. Nat Commun, 8, 2017
1OTT	Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex 分子名称: CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... 著者 Dutzler, R, Campbell, E.B, MacKinnon, R. 登録日 2003-03-23 公開日 2003-04-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Gating the Selectivity Filter in ClC Chloride Channels Science, 300, 2003
1Z7Y	Crystal Structure of the Arabidopsis thaliana O-Acetylserine Sulfhydrylase K46A mutant 分子名称: Cysteine synthase, N-[(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXYPHOSPHORANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLENE]METHIONINE 著者 Bonner, E.R, Cahoon, R.E, Knapke, S.M, Jez, J.M. 登録日 2005-03-28 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular Basis of Cysteine Biosynthesis in Plants: STRUCTURAL AND FUNCTIONAL ANALYSIS OF O-ACETYLSERINE SULFHYDRYLASE FROM ARABIDOPSIS THALIANA. J.Biol.Chem., 280, 2005
1Z96	Crystal structure of the Mud1 UBA domain 分子名称: UBA-domain protein mud1 著者 Trempe, J.-F, Brown, N.R, Lowe, E.D, Noble, M.E.M, Gordon, C, Campbell, I.D, Johnson, L.N, Endicott, J.A. 登録日 2005-03-31 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain Embo J., 24, 2005
7UMS	Structure of the VP5*/VP8* assembly from the human rotavirus strain CDC-9 in complex with antibody 41 - Upright conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 41 heavy chain, ... 著者 Jenni, S, Zongli, L, Wang, Y, Bessey, T, Salgado, E.N, Schmidt, A.G, Greenberg, H.B, Jiang, B, Harrison, S.C. 登録日 2022-04-07 公開日 2022-07-27 最終更新日 2022-08-31 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion. J.Virol., 96, 2022
7UMT	Structure of the VP5*/VP8* assembly from the human rotavirus strain CDC-9 - Reversed conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... 著者 Jenni, S, Zongli, L, Wang, Y, Bessey, T, Salgado, E.N, Schmidt, A.G, Greenberg, H.B, Jiang, B, Harrison, S.C. 登録日 2022-04-07 公開日 2022-07-27 最終更新日 2022-08-31 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion. J.Virol., 96, 2022

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