PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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5CGN	Structure of quasiracemic Ala-Magainin 2 with a beta amino acid substitution at position 8 分子名称: CHLORIDE ION, D-Ala-Magainin Derivative, L-ACPC8-Ala-Magainin 著者 Hayouka, Z, Thomas, N.C, Mortenson, D.E, Satyshur, K.A, Weisblum, B, Forest, K.T, Gellman, S.H. 登録日 2015-07-09 公開日 2015-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif. J.Am.Chem.Soc., 137, 2015
3OO6	Crystal structures and biochemical characterization of the bacterial solute receptor AcbH reveal an unprecedented exclusive substrate preference for b-D-galactopyranose 分子名称: ABC transporter binding protein AcbH, SULFATE ION, beta-D-galactopyranose 著者 Vahedi-Faridi, A, Bulut, H, Licht, A. 登録日 2010-08-30 公開日 2010-12-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structures of the bacterial solute receptor AcbH displaying an exclusive substrate preference for beta-D-galactopyranose J.Mol.Biol., 406, 2011
6IBM	Crystal structure of human alpha-galactosidase A in complex with alpha-galactose configured cyclosulfate ME776 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Rowland, R.J, Wu, L, Davies, G.J. 登録日 2018-11-30 公開日 2019-10-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Alpha-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal alpha-galactosidase A in Fabry disease Chem Sci, 2019
3OVR	Crystal Structure of hRPE and D-Xylulose 5-Phosphate Complex 分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, 5-O-phosphono-D-xylulose, FE (II) ION, ... 著者 Liang, W.G, Ouyang, S.Y, Shaw, N, Joachimiak, A, Zhang, R.G, Liu, Z.J. 登録日 2010-09-17 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Conversion of D-ribulose 5-phosphate to D-xylulose 5-phosphate: new insights from structural and biochemical studies on human RPE Faseb J., 25, 2011
6IBT	Crystal structure of human alpha-galactosidase A in complex with alpha-galactose configured cyclophellitol aziridine ME737 分子名称: (1~{S},2~{S},3~{S},4~{S},5~{R},6~{S})-5-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3,4-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Rowland, R.J, Wu, L, Davies, G.J. 登録日 2018-11-30 公開日 2019-10-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Alpha-d-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal alpha-galactosidase A in Fabry disease Chem Sci, 2019
4Z03	C. bescii Family 3 pectate lyase double mutant K108A in complex with trigalacturonic acid 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2015-03-25 公開日 2015-12-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The catalytic mechanism and unique low pH optimum of Caldicellulosiruptor bescii family 3 pectate lyase. Acta Crystallogr.,Sect.D, 71, 2015
3B9W	The 1.3 A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins 分子名称: Ammonium transporter family, GLYCEROL, octyl beta-D-glucopyranoside 著者 Lupo, D, Winkler, F.K. 登録日 2007-11-07 公開日 2007-11-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The 1.3-A resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH3 transport by Rhesus family proteins. Proc.Natl.Acad.Sci.Usa, 104, 2007
3P10	Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL694, 2-(thiophen-2-yl)phenyl methanol 分子名称: (2-thiophen-2-ylphenyl)methanol, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-09-29 公開日 2010-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
5O52	Glycogen Phosphorylase b in complex with 33b 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... 著者 Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. 登録日 2017-05-31 公開日 2017-09-27 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
1MQP	THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-6 分子名称: GLYCEROL, alpha-D-glucuronidase 著者 Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. 登録日 2002-09-17 公開日 2003-09-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implications. J.Biol.Chem., 279, 2004
3PAG	Crystal structure of the V130D mutant of OXA-24/40 in complex with doripenem 分子名称: (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase, SULFATE ION 著者 Powers, R.A, Leonard, D.A, Schneider, K.D. 登録日 2010-10-19 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with Doripenem. J.Mol.Biol., 406, 2011
5CX8	Structure of RagB, a major immunodominant virulence factor of Porphyromonas gingivalis. 分子名称: 3-deoxy-5-O-phosphono-beta-D-ribofuranose, 3-deoxy-beta-D-glucopyranose, 6-O-phosphono-D-tagatose, ... 著者 Goulas, T, Garcia-Ferrer, I, Hutcherson, J.A, Potempa, B.A, Potempa, J, Scott, D.A, Gomis-Ruth, F.X. 登録日 2015-07-28 公開日 2015-10-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis. Mol Oral Microbiol, 31, 2016
2ZE9	Crystal structure of H168A mutant of phospholipase D from Streptomyces antibioticus, as a complex with phosphatidylcholine 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Phospholipase D 著者 Suzuki, A, Toda, H, Iwasaki, Y, Yamane, T, Yamane, T. 登録日 2007-12-06 公開日 2007-12-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of phospholipase D from streptomyces antibioticus To be Published
5NHC	Crystal structure of xylose isomerase from Piromyces E2 in complex with two Co2+ ions and xylulose 分子名称: 4-HYDROXYPROLINE, COBALT (II) ION, D-XYLULOSE, ... 著者 Rozeboom, H.J, Janssen, D.B. 登録日 2017-03-21 公開日 2017-11-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Metal Dependence of the Xylose Isomerase from Piromyces sp. E2 Explored by Activity Profiling and Protein Crystallography. Biochemistry, 56, 2017
3OVW	ENDOGLUCANASE I NATIVE STRUCTURE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I 著者 Davies, G.J, Schulein, M. 登録日 1997-10-06 公開日 1998-04-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the endoglucanase I from Fusarium oxysporum: native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 A resolution. Biochemistry, 36, 1997
3P0Z	Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytidine and FOL955, 4-(1H-imidazol)-1-yl)phenol 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 4-(1H-IMIDAZOL-1-YL)PHENOL, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-09-29 公開日 2010-10-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
4NZ5	Structure of Vibrio cholerae chitin de-N-acetylase in complex with 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) and cadmium ion 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, ACETATE ION, CADMIUM ION, ... 著者 Albesa-Jove, D, Andres, E, Biarnes, X, Planas, A, Guerin, M.E. 登録日 2013-12-11 公開日 2014-11-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.874 Å) 主引用文献 Vibrio cholerae protein To be Published
1FX6	AQUIFEX AEOLICUS KDO8P SYNTHASE 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, PHOSPHATE ION 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-25 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
5OX4	Glycogen Phosphorylase in complex with CK900 分子名称: (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(4-aminophenyl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... 著者 Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. 登録日 2017-09-05 公開日 2018-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
1FY6	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH CADMIUM AND A5P 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-28 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
4IM7	Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-MANNONIC ACID, Hypothetical oxidoreductase ydfI, ... 著者 Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. 登録日 2013-01-02 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate To be Published
1FXQ	AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP AND A5P 分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE 著者 Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. 登録日 2000-09-26 公開日 2001-04-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
5FQG	The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, FORMIC ACID 著者 Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. 登録日 2015-12-10 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens J.Mol.Biol., 428, 2016
1V03	Crystal structure of the Sorghum bicolor dhurrinase 1 分子名称: ACETONITRILE, DHURRINASE, PHENOL, ... 著者 Moriniere, J, Verdoucq, L, Bevan, D.R, Esen, A, Henrissat, B, Czjzek, M. 登録日 2004-03-22 公開日 2004-05-20 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Determinants of Substrate Specificity in Family 1 Beta-Glucosidases: Novel Insights from the Crystal Structure of Sorghum Dhurrinase-1, a Plant Beta-Glucosidase with Strict Specificity, in Complex with its Natural Substrate J.Biol.Chem., 279, 2004
4BNY	Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d) pyrimidin-4-yl)morpholine at 1.8A resolution 分子名称: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG, 4-(2-phenylthieno[3,2-d]pyrimidin-4-yl)morpholine 著者 Cukier, C.D, Schnell, R, Lindqvist, Y, Schneider, G. 登録日 2013-05-17 公開日 2013-09-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-Acyl-Acp Reductase from Pseudomonas Aeruginosa Acs Chem.Biol., 8, 2013

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