3PAG

Crystal structure of the V130D mutant of OXA-24/40 in complex with doripenem

Summary for 3PAG

Related3ISG 3PAE
DescriptorBeta-lactamase, (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywordshydrolase, carbapenemase, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological sourceAcinetobacter baumannii
Total number of polymer chains2
Total molecular weight56803.04
Authors
Powers, R.A.,Leonard, D.A.,Schneider, K.D. (deposition date: 2010-10-19, release date: 2011-01-19, Last modification date: 2016-10-05)
Primary citation
Schneider, K.D.,Ortega, C.J.,Renck, N.A.,Bonomo, R.A.,Powers, R.A.,Leonard, D.A.
Structures of the Class D Carbapenemase OXA-24 from Acinetobacter baumannii in Complex with Doripenem.
J.Mol.Biol., 406:583-594, 2011
PubMed: 21215758 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2010.12.042
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227604.6%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution