6C7P
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3P9T
| SmeT-Triclosan complex | 分子名称: | Repressor, SULFATE ION, TRICLOSAN | 著者 | Hernandez, A, Ruiz, F.M, Romero, A, Martinez, J.L. | 登録日 | 2010-10-18 | 公開日 | 2011-08-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia. Plos Pathog., 7, 2011
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6H0U
| Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor | 分子名称: | (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ... | 著者 | Marcovich, I, Demitri, N, De Zorzi, R, Storici, P. | 登録日 | 2018-07-10 | 公開日 | 2019-05-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem, 14, 2019
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5LZX
| Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2016-10-02 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | 主引用文献 | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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8BGN
| N,N-diacetylchitobiose deacetylase from Pyrococcus chitonophagus | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Diacetylchitobiose deacetylase, ... | 著者 | Rypniewski, W, Bejger, M, Biniek-Antosiak, K. | 登録日 | 2022-10-28 | 公開日 | 2023-01-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural, Thermodynamic and Enzymatic Characterization of N , N -Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus. Int J Mol Sci, 23, 2022
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5LVG
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6M5N
| Apo-Form Structure of Borneol Dehydrogenase | 分子名称: | ACETATE ION, Borneol dehydrogenase, SULFATE ION | 著者 | Khine, A.A, Huang, K.F, Ko, T.P, Chen, H.P. | 登録日 | 2020-03-11 | 公開日 | 2020-07-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structural characterization of borneol dehydrogenase from Pseudomonas sp. TCU-HL1 Acta Crystallogr.,Sect.F, 76, 2020
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8EBU
| XPC release from Core7-XPA-DNA (Cy5) | 分子名称: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | 著者 | Kim, J, Yang, W. | 登録日 | 2022-08-31 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
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5LVK
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8BEF
| Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | 著者 | Klusch, N, Kuehlbrandt, W. | 登録日 | 2022-10-21 | 公開日 | 2023-01-11 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (2.13 Å) | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution. Nat.Plants, 9, 2023
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6MG9
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8BGO
| N,N-diacetylchitobiose deacetylase from Pyrococcus chitonophagus with substrate N,N-diacetylchitobiose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Diacetylchitobiose deacetylase, ZINC ION | 著者 | Rypniewski, W, Bejger, M, Biniek-Antosiak, K. | 登録日 | 2022-10-28 | 公開日 | 2023-01-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Structural, Thermodynamic and Enzymatic Characterization of N , N -Diacetylchitobiose Deacetylase from Pyrococcus chitonophagus. Int J Mol Sci, 23, 2022
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8B3L
| Hen Egg White Lysozyme 2s in situ crystallization | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Henkel, A, Galchenkova, M, Yefanov, O, Hakanpaeae, J, Chapman, H.N, Oberthuer, D. | 登録日 | 2022-09-16 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | JINXED: just in time crystallization for easy structure determination of biological macromolecules. Iucrj, 10, 2023
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6H1U
| GlnH bound to Asp, Mycobacterium tuberculosis | 分子名称: | ASPARTIC ACID, Probable glutamine-binding lipoprotein GlnH (GLNBP) | 著者 | O'Hare, H.M, Wallis, R, Lin, L.Y, Newland-Smith, Z. | 登録日 | 2018-07-12 | 公開日 | 2018-08-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | An Aspartate-Specific Solute-Binding Protein Regulates Protein Kinase G Activity To Control Glutamate Metabolism in Mycobacteria. MBio, 9, 2018
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5M3C
| Structure of the hybrid domain (GGDEF-EAL) of PA0575 from Pseudomonas aeruginosa PAO1 at 2.8 Ang. with GTP and Ca2+ bound to the active site of the GGDEF domain | 分子名称: | CALCIUM ION, Diguanylate cyclase, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Giardina, G, Brunotti, P, Cutruzzola, F, Rinaldo, S. | 登録日 | 2016-10-14 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa. FEBS J., 285, 2018
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5LYE
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8EBY
| XPC release from Core7-XPA-DNA (AP) | 分子名称: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | 著者 | Kim, J, Yang, W. | 登録日 | 2022-08-31 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature, 617, 2023
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8K9R
| Cryo EM structure of the products-bound PGAP1(Bst1)-H443N from Chaetomium thermophilum | 分子名称: | 2-amino-2-deoxy-alpha-D-glucopyranose, 2-azanylethyl [(2R,3S,4S,5S,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl hydrogen phosphate, 2-azanylethyl [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphate, ... | 著者 | Li, T, Hong, J, Qu, Q, Li, D. | 登録日 | 2023-08-01 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Molecular basis of the inositol deacylase PGAP1 involved in quality control of GPI-AP biogenesis. Nat Commun, 15, 2024
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6BIG
| Crystal structure of cobalt-substituted Synechocystis ACO | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, COBALT (II) ION | 著者 | Sui, X, Shi, W, Kiser, P.D. | 登録日 | 2017-11-02 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Preparation and characterization of metal-substituted carotenoid cleavage oxygenases. J. Biol. Inorg. Chem., 23, 2018
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8P1G
| Crystal structure of inactive TtCE16 in complex with acetate | 分子名称: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Dimarogona, M, Kosinas, C, Pentari, C, Zerva, A, Topakas, E, Karampa, P. | 登録日 | 2023-05-12 | 公開日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The role of CE16 exo-deacetylases in hemicellulolytic enzyme mixtures revealed by the biochemical and structural study of the novel TtCE16B esterase. Carbohydr Polym, 327, 2024
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6M9T
| Crystal structure of EP3 receptor bound to misoprostol-FA | 分子名称: | (11alpha,12alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, OLEIC ACID, ... | 著者 | Audet, M, White, K.L, Breton, B, Zarzycka, B, Han, G.W, Lu, Y, Gati, C, Batyuk, A, Popov, P, Velasquez, J, Manahan, D, Hu, H, Weierstall, U, Liu, W, Shui, W, Katrich, V, Cherezov, V, Hanson, M.A, Stevens, R.C. | 登録日 | 2018-08-24 | 公開日 | 2018-12-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor. Nat. Chem. Biol., 15, 2019
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7LOX
| The structure of Agmatinase from E. Coli at 3.2 A displaying guanidine in the active site | 分子名称: | Agmatinase, GUANIDINE, MANGANESE (II) ION | 著者 | Maturana, P, Figueroa, M, Gonzalez-Ordenes, F, Villalobos, P, Martinez-Oyanedel, J, Uribe, E.A, Castro-Fernandez, V. | 登録日 | 2021-02-11 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal Structure of Escherichia coli Agmatinase: Catalytic Mechanism and Residues Relevant for Substrate Specificity. Int J Mol Sci, 22, 2021
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6LLC
| Discovery of A Dual Inhibitor of NQO1 and GSTP1 for Treating Malignant Glioblastoma | 分子名称: | 5-methyl-N-(5-nitro-1,3-thiazol-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1, ... | 著者 | Ye, K, Li, H. | 登録日 | 2019-12-23 | 公開日 | 2020-11-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma. J Hematol Oncol, 13, 2020
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5LZ2
| Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 | 分子名称: | 3-cyano-~{N}-cyclopropyl-benzenesulfonamide, CHLORIDE ION, Platelet-activating factor acetylhydrolase, ... | 著者 | Woolford, A, Day, P. | 登録日 | 2016-09-29 | 公開日 | 2016-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). J. Med. Chem., 59, 2016
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8JPZ
| The thermostability mutant Gox_M8 from Aspergillus niger | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Tu, T, Yan, Y.R. | 登録日 | 2023-06-13 | 公開日 | 2023-12-20 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Revealing the pH-Dependent Activity Mechanism of a Ferrari Oxidoreductase Enzyme-Glucose Oxidase To Be Published
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