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8VTT
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Meis1 homeobox domain bound to neomycin fragment
分子名称: Homeobox protein Meis1, RIBOSTAMYCIN, SULFATE ION
著者Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N, Sadek, H.A.
登録日2024-01-27
公開日2024-02-14
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals
to be published
8XXN
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Cryo-EM structure of the human 43S ribosome with PDCD4
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J.
登録日2024-01-18
公開日2024-05-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation.
Cell Res., 34, 2024
9NSE
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BU of 9nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, ETHYL-ISOSELENOUREA COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLIC ACID, ...
著者Li, H, Raman, C.S, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L.
登録日1999-01-13
公開日2000-10-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
8VBT
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BU of 8vbt by Molmil
Structure of the monofunctional Staphylococcus aureus PBP1 in its apo form
分子名称: Penicillin-binding protein 1
著者Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
登録日2023-12-12
公開日2024-05-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024
9BAF
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BU of 9baf by Molmil
Solution NMR structure of conofurin-Delta
分子名称: Alpha-conotoxin LvIA
著者Harvey, P.J, Craik, D.J, Hone, A.J, McIntosh, J.M.
登録日2024-04-04
公開日2024-07-03
実験手法SOLUTION NMR
主引用文献Design, Synthesis, and Structure-Activity Relationships of Novel Peptide Derivatives of the Severe Acute Respiratory Syndrome-Coronavirus-2 Spike-Protein that Potently Inhibit Nicotinic Acetylcholine Receptors.
J.Med.Chem., 67, 2024
8WP0
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BU of 8wp0 by Molmil
Structure of the Arabidopsis E529Q/E1174Q ABCB19 in the ATP bound state
分子名称: ABC transporter B family member 19, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Ying, W, Wei, H, Liu, X, Sun, L.
登録日2023-10-08
公開日2024-03-13
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export.
Science, 383, 2024
9IIL
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BU of 9iil by Molmil
Structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with nicotinamide adenine dinucleotide in the presence of poly(ethylene glycol) at 2.20 A resolution
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Viswanathan, V, Kumari, A, Singh, A, Kumar, A, Sharma, P, Chopra, S, Jeyakanthan, J, Sharma, S, Raje, C.I, Singh, T.P.
登録日2024-06-20
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with nicotinamide adenine dinucleotide in the presence of poly(ethylene glycol) at 2.20 A resolution
To Be Published
8WDU
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BU of 8wdu by Molmil
Photosynthetic LH1-RC complex from the purple sulfur bacterium Allochromatium vinosum purified by sucrose density
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, Antenna complex alpha/beta subunit, ...
著者Tani, K, Kanno, R, Harada, A, Kobayashi, A, Minamino, A, Nakamura, N, Ji, X.-C, Purba, E.R, Hall, M, Yu, L.-J, Madigan, M.T, Mizoguchi, A, Iwasaki, K, Humbel, B.M, Kimura, Y, Wang-Otomo, Z.-Y.
登録日2023-09-16
公開日2024-02-21
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献High-resolution structure and biochemical properties of the LH1-RC photocomplex from the model purple sulfur bacterium, Allochromatium vinosum.
Commun Biol, 7, 2024
8VTS
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BU of 8vts by Molmil
Meis1 homeobox domain bound to paromomycin fragment
分子名称: 1,2-ETHANEDIOL, Homeobox protein Meis1, ISOPROPYL ALCOHOL, ...
著者Tomchick, D.R, Ahmed, M.S, Nguyen, N.U.N.
登録日2024-01-27
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Identification of FDA-Approved Drugs That Induce Heart Regeneration in Mammals
to be published
8VFK
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BU of 8vfk by Molmil
Crystal Structure of Delta 109-117 D-Dopachrome Tautomerase (D-DT)
分子名称: CITRATE ANION, D-dopachrome decarboxylase, SODIUM ION
著者Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G.
登録日2023-12-21
公開日2024-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
9IIM
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BU of 9iim by Molmil
Structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with nicotinamide adenine dinucleotide at 2.74 A resolution.
分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Viswanathan, V, Kumari, A, Singh, A, Kumar, A, Sharma, P, Chopra, S, Jeyakanthan, J, Sharma, S, Raje, C.I, Singh, T.P.
登録日2024-06-20
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with nicotinamide adenine dinucleotide at 2.74 A resolution.
To Be Published
8VSH
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BU of 8vsh by Molmil
Crystal structure of Shewanella benthica Group 1 truncated hemoglobin C51S C71S variant with trans heme D
分子名称: Group 1 truncated hemoglobin, {3-[(2R,5'R)-9',14'-diethenyl-5'-hydroxy-5',10',15',19'-tetramethyl-5-oxo-4,5-dihydro-3H-spiro[furan-2,4'-[21,22,23,24]tetraazapentacyclo[16.2.1.13,6.18,11.113,16]tetracosa[1,3(24),6,8,10,12,14,16(22),17,19]decaen]-20'-yl-kappa~4~N~21'~,N~22'~,N~23'~,N~24'~]propanoato}iron
著者Lecomte, J.T.J, Martinez, J.E, Schlessman, J.L, Schultz, T.D, Siegler, M.A.
登録日2024-01-24
公開日2024-04-03
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Heme d formation in a Shewanella benthica hemoglobin.
J.Inorg.Biochem., 259, 2024
8W9O
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BU of 8w9o by Molmil
structure of AtHKT1;1 in KCl at 2.8 Angstroms resolution
分子名称: POTASSIUM ION, Sodium transporter HKT1
著者Wang, J, Su, N, Guo, J.
登録日2023-09-05
公開日2024-02-14
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures and ion transport mechanisms of plant high-affinity potassium transporters.
Mol Plant, 17, 2024
9HVP
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BU of 9hvp by Molmil
Design, activity and 2.8 Angstroms crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease
分子名称: HIV-1 Protease, benzyl [(1R,4S,6S,9R)-4,6-dibenzyl-5-hydroxy-1,9-bis(1-methylethyl)-2,8,11-trioxo-13-phenyl-12-oxa-3,7,10-triazatridec-1-yl]carbamate
著者Neidhart, D.J, Erickson, J.
登録日1990-11-06
公開日1992-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease.
Science, 249, 1990
8YWO
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BU of 8ywo by Molmil
Crystal structure of L-azetidine-2-carboxylate hydrolase soaked in (S)-azetidine-2-carboxylic acid
分子名称: (2S)-azetidine-2-carboxylic acid, (S)-2-haloacid dehalogenase
著者Toyoda, M, Mizutani, K, Mikami, B, Wackett, L.P, Esaki, N, Kurihara, T.
登録日2024-03-31
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Research for the crystal structure of L-azetidine-2-carboxylate hydrolase
To Be Published
8W5K
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BU of 8w5k by Molmil
Cryo-EM structure of the yeast TOM core complex crosslinked by BS3 (from TOM-TIM23 complex)
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ...
著者Wang, Q, Guan, Z.Y, Zhuang, J.J, Huang, R, Yin, P.
登録日2023-08-27
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The architecture of substrate-engaged TOM-TIM23 supercomplex reveals preprotein proximity sites for mitochondrial protein translocation.
Cell Discov, 10, 2024
8W9N
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BU of 8w9n by Molmil
Structure of AtHKT1;1 in NaCl at 2.7 Angstroms resolution
分子名称: SODIUM ION, Sodium transporter HKT1
著者Wang, J, Su, N, Guo, J.
登録日2023-09-05
公開日2024-02-14
最終更新日2024-08-07
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures and ion transport mechanisms of plant high-affinity potassium transporters.
Mol Plant, 17, 2024
8VQX
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BU of 8vqx by Molmil
Structure of SARS-CoV-2 main protease with potent peptide aldehyde inhibitor
分子名称: 1,2-ETHANEDIOL, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, ...
著者Dougan, D.R, Lane, W.
登録日2024-01-19
公開日2024-08-07
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Exploiting high-energy hydration sites for the discovery of potent peptide aldehyde inhibitors of the SARS-CoV-2 main protease with cellular antiviral activity.
Bioorg.Med.Chem., 103, 2024
8Z77
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BU of 8z77 by Molmil
The structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum (pmTcDH), activated by crystals soaking with 1 mM CuCl2 and Na ascorbate during 12 hours
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, Twin-arginine translocation signal domain-containing protein
著者Varfolomeeva, L.A, Solovieva, A.Y, Shipkov, N.S, Dergousova, N.I, Minyaev, M.E, Boyko, K.M, Tikhonova, T.V, Popov, V.O.
登録日2024-04-19
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum (pmTcDH), activated by crystals soaking with 1 mM CuCl2 and Na ascorbate during 12 hours
To Be Published
8WQM
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BU of 8wqm by Molmil
Complex structure of AtHPPD with Atovaquone
分子名称: 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, G.-F, Lin, H.-Y, Dong, J.
登録日2023-10-11
公開日2024-03-13
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Complex structure of AtHPPD with Atovaquone
To Be Published
9IJ6
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BU of 9ij6 by Molmil
Crystal structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with Adenosine phosphate at 2.40 A resolution.
分子名称: ADENOSINE MONOPHOSPHATE, Glyceraldehyde-3-phosphate dehydrogenase, MAGNESIUM ION, ...
著者Viswanathan, V, Kumari, A, Singh, A, Kumar, A, Sharma, P, Chopra, S, Jeyakanthan, J, Sharma, S, Raje, C.I, Singh, T.P.
登録日2024-06-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the complex of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii with Adenosine phosphate at 2.40 A resolution.
To Be Published
8WNF
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BU of 8wnf by Molmil
Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in apo form
分子名称: ACETATE ION, GLYCEROL, Isoleucine--tRNA ligase, ...
著者Guo, Y, Li, S, Zhang, T.
登録日2023-10-05
公開日2024-02-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase.
Febs Lett., 598, 2024
9BKM
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DHODH in complex with Ligand 10
分子名称: (2M,6P)-2-(2-chloro-6-fluorophenyl)-6-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-7-fluoro-4-(propan-2-yl)isoquinolin-1(2H)-one, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ...
著者Shaffer, P.L.
登録日2024-04-29
公開日2024-07-03
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML.
J.Med.Chem., 67, 2024
8VBZ
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BU of 8vbz by Molmil
Crystal structure of the transpeptidase domain of a S310A mutant of PBP2 from Neisseria gonorrhoeae strain H041
分子名称: Probable peptidoglycan D,D-transpeptidase PenA
著者Stratton, C, Bala, S, Davies, C.
登録日2023-12-13
公開日2024-03-20
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041.
Acs Infect Dis., 10, 2024
8X61
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Cryo-EM structure of ATP-bound FtsE(E163Q)X
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX
著者Zhang, Z.Y, Chen, Y.T.
登録日2023-11-20
公開日2024-05-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structure and activity of the septal peptidoglycan hydrolysis machinery crucial for bacterial cell division.
Plos Biol., 22, 2024

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件を2024-08-21に公開中

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