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8VBZ

Crystal structure of the transpeptidase domain of a S310A mutant of PBP2 from Neisseria gonorrhoeae strain H041

Summary for 8VBZ
Entry DOI10.2210/pdb8vbz/pdb
DescriptorProbable peptidoglycan D,D-transpeptidase PenA (2 entities in total)
Functional Keywordspenicillin-binding protein, transpeptidase, complex, hydrolase
Biological sourceNeisseria gonorrhoeae
Total number of polymer chains1
Total formula weight35345.50
Authors
Stratton, C.,Bala, S.,Davies, C. (deposition date: 2023-12-13, release date: 2024-03-20, Last modification date: 2024-04-24)
Primary citationTurner, J.M.,Stratton, C.M.,Bala, S.,Cardenas Alvarez, M.,Nicholas, R.A.,Davies, C.
Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041.
Acs Infect Dis., 10:1298-1311, 2024
Cited by
PubMed: 38446051
DOI: 10.1021/acsinfecdis.3c00713
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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PDB entries from 2024-04-24

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