PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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9BJA	C. difficile Tcdb cysteine protease domain in complex with IP6 分子名称: INOSITOL HEXAKISPHOSPHATE, Toxin B 著者 Veyron, S, Cummer, R. 登録日 2024-04-25 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-activity relationship of inositol thiophosphate analogs as allosteric activators of Clostridioides difficile Toxin B Chemrxiv, 2024
9EOG	PHF type tau filament from R406W mutant 分子名称: Microtubule-associated protein tau 著者 Qi, C, Scheres, S.H.W, Michel, G. 登録日 2024-03-14 公開日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024
9ICS	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MNCL2 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
9ERO	CTE type III tau filament from vacuolar tauopathy 分子名称: Microtubule-associated protein tau 著者 Qi, C, Scheres, H.W.S, Goedert, M. 登録日 2024-03-24 公開日 2024-05-29 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G. Acta Neuropathol, 147, 2024
9B64	GluA2 flip Q in complex with TARPgamma2 at pH5, class23, structure of LBD-TMD-TARPgamma2 分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T, Greger, I.H. 登録日 2024-03-23 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization To Be Published
9B6A	GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of LBD-TMD-TARPgamma2 分子名称: Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit 著者 Nakagawa, T, Greger, I.H. 登録日 2024-03-23 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization To Be Published
8XX0	Crystal structure of anti-IgE antibody HMK-12 Fab complexed with IgE F(ab')2 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SPE7 immunoglobulin E F(ab')2 heavy chain, ... 著者 Hirano, T, Koyanagi, A, Kasai, M, Okumura, K. 登録日 2024-01-17 公開日 2024-07-31 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Allosteric inhibition of the IgE-Fc epsilon RI interactions by targeting epitopes on IgE F(ab')2 regions To Be Published
9ICO	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1995-12-16 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
8XM1	Phytase mutant APPAmut4 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phytase 著者 Tu, T, Wang, Q. 登録日 2023-12-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The mutant crystal structure of phytase APPAmut4 from Yersinia intermedia To Be Published
9C61	Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26 分子名称: (4R)-4-[4-(5-fluoro-1H-indol-3-yl)piperidine-1-carbonyl]piperidin-2-one, Non-specific serine/threonine protein kinase, UNKNOWN ATOM OR ION 著者 Zeng, H, Dong, A, Kutera, M, Ilyassov, O, Seitova, A, Loppnau, P, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Halabelian, L. 登録日 2024-06-07 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the human LRRK2 WDR domain in complex with CACHE1193-26 To be published
9F48	KS + AT di-domain of polyketide synthase 13 in Mycobacterium tuberculosis 分子名称: Polyketide synthase Pks13 著者 Johnston, H.E, Futterer, K. 登録日 2024-04-26 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 CryoEM structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis To be published
9B36	Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map. 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. 登録日 2024-03-18 公開日 2024-05-22 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.29 Å) 主引用文献 Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
9JDW	CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH ALPHA-AMINO BUTYRIC ACID 分子名称: ALPHA-AMINOBUTYRIC ACID, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE) 著者 Fritsche, E, Humm, A, Huber, R. 登録日 1998-10-12 公開日 1999-02-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study. J.Biol.Chem., 274, 1999
9ICI	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND ZNCL2 (1 MILLIMOLAR) 分子名称: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-15 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis. Biochemistry, 35, 1996
8XM2	The mutant crystal structure of phytase APPAmut9 from Yersinia intermedia 分子名称: Phytase 著者 Tu, T, Dong, R.Y. 登録日 2023-12-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The mutant crystal structure of phytase APPAmut9 from Yersinia intermedia To Be Published
9EY6	Crystal structure of human tyrosinase-related protein 1 (TYRP1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5,6-dihydroxyindole-2-carboxylic acid oxidase, ... 著者 Ng, Y.M, Soler-Lopez, M. 登録日 2024-04-09 公開日 2024-05-22 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.228 Å) 主引用文献 Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies. Chembiochem, 25, 2024
8ZAH	Crystal structure of the channel protein CorA from Campylobacter jejuni 分子名称: Magnesium transport protein CorA, SULFATE ION 著者 Ahn, S.Y, Yoon, S.I. 登録日 2024-04-25 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and biochemical analysis of the unique interactions of the Campylobacter jejuni CorA channel protein with divalent cations. Biochem.Biophys.Res.Commun., 723, 2024
8ZNB	Cryo-EM structure of W89F mutated Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH in the steady stage of reaction 分子名称: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Wakabayashi, T, Nakasako, M. 登録日 2024-05-26 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.53 Å) 主引用文献 Mechanism for drastic reduction in catalytic activity of Trp89Phe-mutated glutamate dehydrogenase revealed by crystal structure and cryoEM-sampling of metastable conformation in action To Be Published
9F4J	UP1 in complex with Z416341642 分子名称: (2R)-N,2-dimethyl-N-(propan-2-yl)morpholine-4-sulfonamide, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed 著者 Dunnett, L, Prischi, F. 登録日 2024-04-28 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
9CI8	T cell receptor complex 分子名称: T cell receptor delta constant, T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... 著者 Gully, B.S, Rossjohn, J. 登録日 2024-07-02 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 T cell receptor complex To Be Published
9ICW	DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; NATIVE STRUCTURE 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1995-12-16 公開日 1996-11-15 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity Biochemistry, 35, 1996
8ZM1	Structure of human pyruvate dehydrogenase kinase 2 complexed with compound 6 分子名称: (5~{R})-5-propan-2-ylindeno[1,2-b]pyridin-5-ol, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 著者 Akai, S, Orita, T, Nomura, A, Adachi, T. 登録日 2024-05-22 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Design and synthesis of novel fluorene derivatives as inhibitors of pyruvate dehydrogenase kinase. Bioorg.Med.Chem.Lett., 109, 2024
8ZFM	Caenorhabditis elegans ACR-23 in betaine bound state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ... 著者 Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S. 登録日 2024-05-08 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine To Be Published
9ASB	Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs 分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. 登録日 2024-02-24 公開日 2024-04-17 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024
9AVL	Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs 分子名称: (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zuo, H, Park, J, Frangaj, A, Ye, J, Lu, G, Manning, J.J, Asher, W.B, Lu, Z, Hu, G, Wang, L, Mendez, J, Eng, E, Zhang, Z, Lin, X, Grasucci, R, Hendrickson, W.A, Clarke, O.B, Javitch, J.A, Conigrave, A.D, Fan, Q.R. 登録日 2024-03-04 公開日 2024-04-17 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Promiscuous G-protein activation by the calcium-sensing receptor. Nature, 629, 2024

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