PDB: 55921 件ウェブページステータス検索Chemie searchBIRD

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2Y5K	Orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase 分子名称: 1-[5-(2-METHOXYETHYL)-4-METHYL-THIOPHEN-2-YL]SULFONYL-3-[4-METHOXY-6-(METHYLCARBAMOYLAMINO)PYRIDIN-2-YL]UREA, FRUCTOSE-1,6-BISPHOSPHATASE 1 著者 Ruf, A, Hebeisen, P, Haap, W, Kuhn, B, Mohr, P, Wessel, H.P, Zutter, U, Kirchner, S, Benz, J, Joseph, C, Alvarez-Sanchez, R, Gubler, M, Schott, B, Benardeau, A, Tozzo, E, Kitas, E. 登録日 2011-01-14 公開日 2011-05-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase. Bioorg.Med.Chem.Lett., 21, 2011
1JVC	Dimeric DNA Quadruplex Containing Major Groove-Aligned A.T.A.T and G.C.G.C Tetrads Stabilized by Inter-Subunit Watson-Crick A:T and G:C Pairs 分子名称: 5'-D(*GP*AP*GP*CP*AP*GP*GP*T)-3' 著者 Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. 登録日 2001-08-29 公開日 2001-10-24 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Dimeric DNA quadruplex containing major groove-aligned A-T-A-T and G-C-G-C tetrads stabilized by inter-subunit Watson-Crick A-T and G-C pairs. J.Mol.Biol., 312, 2001
2W3L	Crystal Structure of Chimaeric Bcl2-xL and Phenyl Tetrahydroisoquinoline Amide Complex 分子名称: 1-(2-{[(3S)-3-(aminomethyl)-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}phenyl)-4-chloro-5-methyl-N,N-diphenyl-1H-pyrazole-3-carboxamide, APOPTOSIS REGULATOR BCL-2 著者 Porter, J, Payne, A, de Candole, B, Ford, D, Hutchinson, B, Trevitt, G, Turner, J, Edwards, C, Watkins, C, Whitcombe, I, Davis, J, Stubberfield, C, Fisher, M, Lamers, M. 登録日 2008-11-13 公開日 2008-12-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Tetrahydroisoquinoline Amide Substituted Phenyl Pyrazoles as Selective Bcl-2 Inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
1KT9	Crystal Structure of C. elegans Ap4A Hydrolase 分子名称: Diadenosine Tetraphosphate Hydrolase 著者 Bailey, S, Sedelnikova, S.E, Blackburn, G.M, Abdelghany, H.M, Baker, P.J, McLennan, A.G, Rafferty, J.B. 登録日 2002-01-15 公開日 2002-05-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms Structure, 10, 2002
1JWK	Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457A Mutation at Tetrahydrobiopterin Binding Site 分子名称: 1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, GLYCEROL, ... 著者 Aoyagi, M, Arvai, A.S, Ghosh, S, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. 登録日 2001-09-04 公開日 2001-10-31 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457. Biochemistry, 40, 2001
1I76	COMPLEX OF 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID (D-TIC DERIVATIVE) WITH T CATALITIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) 分子名称: 2-(BIPHENYL-4-SULFONYL)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, CALCIUM ION, NEUTROPHIL COLLAGENASE, ... 著者 Gavuzzo, E, Pochetti, G, Mazza, F, Gallina, C, Gorini, B, D'Alessio, S, Pieper, M, Tschesche, H, Tucker, P.A. 登録日 2001-03-08 公開日 2001-03-21 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design. J.Med.Chem., 43, 2000
1K6H	Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA processing 分子名称: RNA (5'-R(P*GP*GP*CP*GP*UP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*GP*CP*GP*CP*C)-3') 著者 Lebars, I, Lamontagne, B, Yoshizawa, S, Abou Elela, S, Fourmy, D. 登録日 2001-10-16 公開日 2001-12-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing. EMBO J., 20, 2001
1K6G	Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing 分子名称: RNA (5'-R(P*GP*GP*CP*GP*UP*CP*AP*UP*GP*AP*GP*UP*CP*CP*AP*UP*GP*GP*CP*GP*CP*C)-3') 著者 Lebars, I, Lamontagne, B, Yoshizawa, S, Abou Elela, S, Fourmy, D. 登録日 2001-10-16 公開日 2001-12-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing. EMBO J., 20, 2001
2XG7	Crystal Structure of BST2-Tetherin Ectodomain expressed in HEK293T cells 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BONE MARROW STROMAL ANTIGEN 2 著者 Steiner, R.A. 登録日 2010-05-31 公開日 2010-10-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural and Functional Studies on the Extracellular Domain of Bst2/Tetherin in Reduced and Oxidized Conformations. Proc.Natl.Acad.Sci.USA, 107, 2010
1K4B	STRUCTURE OF AGUU RNA TETRALOOP, NMR, 20 STRUCTURES 分子名称: 5'-R(*GP*GP*UP*UP*CP*AP*GP*UP*UP*GP*AP*AP*CP*C)-3' 著者 Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. 登録日 2001-10-07 公開日 2001-12-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
1K4A	STRUCTURE OF AGAA RNA TETRALOOP, NMR, 20 STRUCTURES 分子名称: 5'-R(*GP*GP*UP*UP*CP*AP*GP*AP*AP*GP*AP*AP*CP*C)-3' 著者 Wu, H, Yang, P.K, Butcher, S.E, Kang, S, Chanfreau, G, Feigon, J. 登録日 2001-10-07 公開日 2001-12-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 A novel family of RNA tetraloop structure forms the recognition site for Saccharomyces cerevisiae RNase III. EMBO J., 20, 2001
1JJP	A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads 分子名称: 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3' 著者 Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. 登録日 2001-07-09 公開日 2001-09-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads. J.Mol.Biol., 311, 2001
1I94	CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3 分子名称: 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F. 登録日 2001-03-18 公開日 2001-04-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J., 20, 2001
1KTG	Crystal Structure of a C. elegans Ap4A Hydrolase Binary Complex 分子名称: ADENOSINE MONOPHOSPHATE, Diadenosine Tetraphosphate Hydrolase, HYDROXIDE ION, ... 著者 Bailey, S, Sedelnikova, S.E, Blackburn, G.M, Abdelghany, H.M, Baker, P.J, McLennan, A.G, Rafferty, J.B. 登録日 2002-01-16 公開日 2002-05-08 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms Structure, 10, 2002
2YCK	methyltransferase bound with tetrahydrofolate 分子名称: (6S)-5,6,7,8-TETRAHYDROFOLATE, 5-METHYLTETRAHYDROFOLATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE, GLYCEROL, ... 著者 Goetzl, S, Jeoung, J.-H, Hennig, S.E, Dobbek, H. 登録日 2011-03-16 公開日 2011-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
1HYV	HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM 分子名称: CHLORIDE ION, INTEGRASE, SULFATE ION, ... 著者 Molteni, V, Greenwald, J, Rhodes, D, Hwang, Y, Kwiatkowski, W, Bushman, F.D, Siegel, J.S, Choe, S. 登録日 2001-01-22 公開日 2001-04-04 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain. Acta Crystallogr.,Sect.D, 57, 2001
2YCJ	methyltransferase bound with methyltetrahydrofolate 分子名称: 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-METHYLTETRAHYDROFOLATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE, GLYCEROL, ... 著者 Goetzl, S, Jeoung, J.-H, Hennig, S.E, Dobbek, H. 登録日 2011-03-16 公開日 2011-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural Basis for Electron and Methyl-Group Transfer in a Methyltransferase System Operating in the Reductive Acetyl-Coa Pathway J.Mol.Biol., 411, 2011
2ZK4	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 15-oxo-eicosatetraenoic acid 分子名称: (5E,8E,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid, Peroxisome proliferator-activated receptor gamma 著者 Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. 登録日 2008-03-12 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
1HVC	CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR 分子名称: HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE 著者 Bhat, T.N, Baldwin, E.T, Erickson, J.W. 登録日 1994-06-22 公開日 1994-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a tethered dimer of HIV-1 proteinase complexed with an inhibitor. Nat.Struct.Biol., 1, 1994
2ZK3	Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with 8-oxo-eicosatetraenoic acid 分子名称: (5E,11E,14E)-8-oxoicosa-5,9,11,14-tetraenoic acid, Peroxisome proliferator-activated receptor gamma 著者 Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. 登録日 2008-03-12 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
1J0P	Three dimensional Structure of the Y43L mutant of Tetraheme Cytochrome c3 from Desulfovibrio vulgaris Miyazaki F 分子名称: Cytochrome c3, ETHANOL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Ozawa, K, Yasukawa, F, Kumagai, J, Ohmura, T, Cusanvich, M.A, Tomimoto, Y, Ogata, H, Higuchi, Y, Akutsu, H. 登録日 2002-11-19 公開日 2003-11-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 Role of the aromatic ring of Tyr43 in tetraheme cytochrome c(3) from Desulfovibrio vulgaris Miyazaki F. Biophys.J., 85, 2003
2Y95	Solution structure of AUCG tetraloop hairpin found in human Xist RNA A-repeats essential for X-inactivation 分子名称: 5'-R(*GP*GP*CP*GP*CP*AP*UP*CP*GP*GP*CP*GP*CP*C)-3' 著者 Duszczyk, M.M, Sattler, M. 登録日 2011-02-11 公開日 2011-10-26 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The Xist RNA A-Repeat Comprises a Novel Aucg Tetraloop Fold and a Platform for Multimerization. RNA, 17, 2011
1J0O	High Resolution Crystal Structure of the wild type Tetraheme Cytochrome c3 from Desulfovibrio vulgaris Miyazaki F 分子名称: Cytochrome c3, ETHANOL, PROTOPORPHYRIN IX CONTAINING FE 著者 Ozawa, K, Yasukawa, F, Kumagai, J, Ohmura, T, Cusanvich, M.A, Tomimoto, Y, Ogata, H, Higuchi, Y, Akutsu, H. 登録日 2002-11-19 公開日 2003-11-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Role of the aromatic ring of Tyr43 in tetraheme cytochrome c(3) from Desulfovibrio vulgaris Miyazaki F. Biophys.J., 85, 2003
3B7V	HIV-1 protease complexed with gem-diol-amine tetrahedral intermediate NLLTQI 分子名称: CHLORIDE ION, GLYCEROL, Protease, ... 著者 Kovalevsky, A.Y, Chumanevich, A.A, Weber, I.T. 登録日 2007-10-31 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Caught in the Act: The 1.5 A Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate. Biochemistry, 46, 2007
2WZC	The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with ADP, 3PG and aluminium tetrafluoride 分子名称: 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Bowler, M.W, Cliff, M.J, Marston, J.P.M, Baxter, N.J, Hownslow, A.M.H, Varga, A.V, Szabo, J, Vas, M, Blackburn, G.M, Waltho, J.P. 登録日 2009-11-27 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis. J.Am.Chem.Soc., 132, 2010

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