1HVC

CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR

Summary for 1HVC

Entry DOI	10.2210/pdb1hvc/pdb
Descriptor	HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE (3 entities in total)
Functional Keywords	hydrolase(acid protease)
Biological source	Human immunodeficiency virus 1
Total number of polymer chains	1
Total formula weight	22756.83
Authors	Bhat, T.N.,Baldwin, E.T.,Erickson, J.W. (deposition date: 1994-06-22, release date: 1994-10-15, Last modification date: 2024-02-07)
Primary citation	Bhat, T.N.,Baldwin, E.T.,Liu, B.,Cheng, Y.S.,Erickson, J.W. Crystal structure of a tethered dimer of HIV-1 proteinase complexed with an inhibitor. Nat.Struct.Biol., 1:552-556, 1994 Cited by PubMed: 7664084 DOI: 10.1038/nsb0894-552 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation