4HIF
 
 | | Ultrahigh-resolution crystal structure of Z-DNA in complex with Zn2+ ions | | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SPERMINE (FULLY PROTONATED FORM), ... | | 著者 | Drozdzal, P, Gilski, M, Kierzek, R, Lomozik, L, Jaskolski, M. | | 登録日 | 2012-10-11 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | | 主引用文献 | Ultrahigh-resolution crystal structures of Z-DNA in complex with Mn(2+) and Zn(2+) ions.
Acta Crystallogr.,Sect.D, 69, 2013
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6AGF
 | | Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1 | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pan, X.J, li, Z.Q, Zhou, Q, Shen, H.Z, Wu, K, Huang, X.S, Chen, J.F, Zhang, J.R, Zhu, X.C, Lei, J.L, Xiong, W, Gong, H.P, Xiao, B.L, Yan, N. | | 登録日 | 2018-08-11 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta 1.
Science, 362, 2018
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2FK6
 | | Crystal Structure of RNAse Z/tRNA(Thr) complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, RIBONUCLEASE Z, ... | | 著者 | Li de la Sierra-Gallay, I, Mathy, N, Pellegrini, O, Condon, C. | | 登録日 | 2006-01-04 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA.
Nat.Struct.Mol.Biol., 13, 2006
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2E7Y
 | | High resolution structure of T. maritima tRNase Z | | 分子名称: | S-1,2-PROPANEDIOL, SULFATE ION, ZINC ION, ... | | 著者 | Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-15 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes
Acta Crystallogr.,Sect.F, 63, 2007
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3CIR
 | | E. coli Quinol fumarate reductase FrdA T234A mutation | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Tomasiak, T.M, Maklashina, E, Cecchini, G, Iverson, T.M. | | 登録日 | 2008-03-11 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II.
J.Biol.Chem., 283, 2008
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1KH5
 | | E. COLI ALKALINE PHOSPHATASE MUTANT (D330N) MIMIC OF THE TRANSITION STATES WITH ALUMINIUM FLUORIDE | | 分子名称: | ALKALINE PHOSPHATASE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E. | | 登録日 | 2001-11-29 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
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1KHJ
 | | E. COLI ALKALINE PHOSPHATASE MUTANT (D153HD330N) MIMIC OF THE TRANSITION STATES WITH ALUMINIUM FLUORIDE | | 分子名称: | ALUMINUM FLUORIDE, Alkaline phosphatase, ZINC ION | | 著者 | Le Du, M.H, Lamoure, C, Muller, B.H, Bulgakov, O.V, Lajeunesse, E, Menez, A, Boulain, J.C. | | 登録日 | 2001-11-30 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Artificial evolution of an enzyme active site: structural studies of three highly active mutants of Escherichia coli alkaline phosphatase.
J.Mol.Biol., 316, 2002
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1KCE
 | | E. COLI THYMIDYLATE SYNTHASE MUTANT E58Q IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | | 著者 | Sage, C.R, Rutenber, E.E, Stout, T.J, Stroud, R.M. | | 登録日 | 1996-10-22 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An essential role for water in an enzyme reaction mechanism: the crystal structure of the thymidylate synthase mutant E58Q.
Biochemistry, 35, 1996
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9NLQ
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9NL5
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5JRD
 | | E. coli Hydrogenase-1 variant P508A | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... | | 著者 | Carr, S.B, Phillips, S.E.V, Armstrong, F.A, Evans, R.M, Brooke, E.J, Islam, S.T.A. | | 登録日 | 2016-05-06 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Importance of the Active Site "Canopy" Residues in an O2-Tolerant [NiFe]-Hydrogenase.
Biochemistry, 56, 2017
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3CW5
 | | E. coli Initiator tRNA | | 分子名称: | Initiator tRNA | | 著者 | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | | 登録日 | 2008-04-21 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis.
Nucleic Acids Res., 36, 2008
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8RND
 | | Cathepsin S in complex with NNPI-C10 inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Cathepsin S, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Petruzzella, A, Lau, K, Pojer, F, Oricchio, E. | | 登録日 | 2024-01-09 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins.
Nat.Chem.Biol., 20, 2024
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9NLB
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9NLJ
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9NLS
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9NKL
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9NJF
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9NJV
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1KMK
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1KMJ
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3D27
 | | E. coli methionine aminopeptidase with Fe inhibitor W29 | | 分子名称: | 4-(3-ethylthiophen-2-yl)benzene-1,2-diol, MANGANESE (II) ION, Methionine aminopeptidase | | 著者 | Ye, Q.Z, Chai, S, He, H.Z. | | 登録日 | 2008-05-07 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
J.Med.Chem., 51, 2008
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8RJ6
 | | E. coli adenylate kinase in complex with ATP and AMP and Mg2+ as a result of enzymatic AP4A hydrolysis. | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | | 登録日 | 2023-12-20 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase.
Sci Adv, 10, 2024
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8RJ4
 | | E. coli adenylate kinase in complex with two ADP molecules and Mg2+ as a result of enzymatic AP4A hydrolysis | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase, CHLORIDE ION, ... | | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | | 登録日 | 2023-12-20 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase.
Sci Adv, 10, 2024
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8RJ9
 | | E. coli adenylate kinase Asp84Ala variant in complex with two ADP molecules as a result of enzymatic AP4A hydrolysis. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase | | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | | 登録日 | 2023-12-20 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Magnesium induced structural reorganization in the active site of adenylate kinase.
Sci Adv, 10, 2024
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