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5A7R
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Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Lambrecht, M.J, Brichacek, M, Barkauskaite, E, Ariza, A, Ahel, I, Hergenrother, P.J.
登録日2015-07-09
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase.
J.Am.Chem.Soc., 137, 2015
5AGQ
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Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes
分子名称: BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A
著者Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M.
登録日2015-02-03
公開日2015-05-06
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
6HX2
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BU of 6hx2 by Molmil
The structure of Dps from Listeria innocua soaked with Cobalt
分子名称: COBALT (II) ION, DNA protection during starvation protein
著者Zeth, K, Okuda, M.
登録日2018-10-15
公開日2019-09-04
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.597 Å)
主引用文献Metal Positions and Translocation Pathways of the Dodecameric Ferritin-like Protein Dps.
Inorg.Chem., 58, 2019
6H4C
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, NICKEL (II) ION, ...
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
2V15
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Terbium binding in Streptococcus suis Dpr protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Havukainen, H, Papageorgiou, A.C, Kauko, A.
登録日2007-05-22
公開日2008-06-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the zinc- and terbium-mediated inhibition of ferroxidase activity in Dps ferritin-like proteins.
Protein Sci., 17, 2008
6H49
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A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
分子名称: Orf20, SULFATE ION
著者Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
登録日2018-07-20
公開日2019-08-28
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
2W18
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Crystal structure of the C-terminal WD40 domain of human PALB2
分子名称: GLYCEROL, PARTNER AND LOCALIZER OF BRCA2
著者Oliver, A.W, Pearl, L.H.
登録日2008-10-15
公開日2009-07-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for Recruitment of Brca2 by Palb2
Embo Rep., 10, 2009
2UX1
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Identification of two zinc-binding sites in the Streptococcus suis Dpr protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Havukainen, H, Kauko, A, Pulliainen, A.T, Haataja, S, Meyer-Klaucke, W, Finne, J, Papageorgiou, A.C.
登録日2007-03-26
公開日2008-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of the Zinc- and Terbium-Mediated Inhibition of Ferroxidase Activity in Dps Ferritin- Like Proteins.
Protein Sci., 17, 2008
5BON
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BU of 5bon by Molmil
Crystal structure of human Nudt15 (MTH2)
分子名称: MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15
著者Carter, M, Jemth, A.-S, Helleday, T, Stenmark, P.
登録日2015-05-27
公開日2015-08-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2.
Nat Commun, 6, 2015
6I8T
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BU of 6i8t by Molmil
THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR
分子名称: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1
著者Casale, E, Papeo, G, Montagnoli, A.
登録日2018-11-21
公開日2019-05-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.
Acs Med.Chem.Lett., 10, 2019
6KMJ
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Crystal structure of Sth1 bromodomain in complex with H3K14Ac
分子名称: GLYCEROL, Histone H3, Nuclear protein STH1/NPS1
著者Chen, G, Li, W, Yan, F, Wang, D, Chen, Y.
登録日2019-07-31
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex.
Structure, 28, 2020
7WVI
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BU of 7wvi by Molmil
Crystal structure of SIA28
分子名称: Heavy chain of SIA28, Light chain of SIA28
著者Chen, Y, Qi, J, Gao, G.F.
登録日2022-02-10
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
6L4P
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Crystal structure of the complex between the axonemal outer-arm dynein light chain-1 and microtubule binding domain of gamma heavy chain
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dynein light chain 1, axonemal, ...
著者Toda, A, Nishikawa, Y, Tanaka, H, Yagi, T, Kurisu, G.
登録日2019-10-19
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.703 Å)
主引用文献The complex of outer-arm dynein light chain-1 and the microtubule-binding domain of the gamma heavy chain shows how axonemal dynein tunes ciliary beating.
J.Biol.Chem., 295, 2020
7CFU
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BU of 7cfu by Molmil
Crystal Structure of FMN-dependent Cysteine Decarboxylases SpaF
分子名称: ARGININE, DNA/pantothenate metabolism flavoprotein, FLAVIN MONONUCLEOTIDE
著者Li, J, Lu, J, Wang, H, Zhu, J.
登録日2020-06-28
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Characterization of FMN-dependent Cysteine Decarboxylases SPAF
To Be Published
1WFQ
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BU of 1wfq by Molmil
Solution structure of the first cold-shock domain of the human KIAA0885 protein (UNR protein)
分子名称: UNR protein
著者Goroncy, A.K, Kigawa, T, Koshiba, S, Tomizawa, T, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-26
公開日2004-11-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The NMR solution structures of the five constituent cold-shock domains (CSD) of the human UNR (upstream of N-ras) protein.
J.Struct.Funct.Genom., 11, 2010
1YDX
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Crystal structure of Type-I restriction-modification system S subunit from M. genitalium
分子名称: CHLORIDE ION, type I restriction enzyme specificity protein MG438
著者Machado, B, Quijada, O, Pinol, J, Fita, I, Querol, E, Carpena, X.
登録日2004-12-27
公開日2005-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of a Putative Type I Restriction-Modification S Subunit from Mycoplasma genitalium
J.Mol.Biol., 351, 2005
7ETJ
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BU of 7etj by Molmil
C5 portal vertex in the partially-enveloped virion capsid
分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
著者Li, Z, Yu, X.
登録日2021-05-13
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for genome packaging, retention, and ejection in human cytomegalovirus.
Nat Commun, 12, 2021
7ETO
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BU of 7eto by Molmil
C1 CVSC-binding penton vertex in the virion capsid of Human Cytomegalovirus
分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ...
著者Li, Z, Yu, X.
登録日2021-05-13
公開日2021-07-14
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis for genome packaging, retention, and ejection in human cytomegalovirus.
Nat Commun, 12, 2021
7EY6
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The portal protein (GP8) of bacteriophage T7
分子名称: Portal protein
著者Liu, H.R, Chen, W.Y.
登録日2021-05-30
公開日2021-09-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural changes in bacteriophage T7 upon receptor-induced genome ejection.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EY8
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portal
分子名称: Portal protein
著者Liu, H.R, Chen, W.Y.
登録日2021-05-30
公開日2021-09-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural changes in bacteriophage T7 upon receptor-induced genome ejection.
Proc.Natl.Acad.Sci.USA, 118, 2021
7CMW
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BU of 7cmw by Molmil
Complex structure of PARP1 catalytic domain with pamiparib
分子名称: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1
著者Feng, Y.C, Peng, H, Hong, Y, Liu, Y.
登録日2020-07-29
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.
J.Med.Chem., 63, 2020
2A5B
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Avidin complexed with 8-oxodeoxyguanosine
分子名称: 2'-DEOXY-8-OXOGUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
2A5C
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Structure of Avidin in complex with the ligand 8-oxodeoxyadenosine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-OXODEOXYADENOSINE, Avidin
著者Conners, R, Hooley, E, Thomas, S, Brady, R.L.
登録日2005-06-30
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
4A0D
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Structure of unliganded human PARG catalytic domain
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ...
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M.
登録日2011-09-08
公開日2012-10-17
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
4B1G
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Structure of unliganded human PARG catalytic domain
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, SULFATE ION
著者Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M.
登録日2012-07-10
公開日2012-12-19
最終更新日2013-01-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012

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