2W18

Crystal structure of the C-terminal WD40 domain of human PALB2

Summary for 2W18

• Entry DOI: 10.2210/pdb2w18/pdb
• Descriptor: PARTNER AND LOCALIZER OF BRCA2, GLYCEROL (3 entities in total)
• Functional Keywords: fanconi anemia, homologous recomination, polymorphism, phosphoprotein, beta-propeller, wd40, fanc-n, nucleus, wd repeat, coiled coil, nuclear protein
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus: Q86YC2
• Total number of polymer chains: 1
• Total formula weight: 39624.26

Authors

Oliver, A.W.,Pearl, L.H. (deposition date: 2008-10-15, release date: 2009-07-28, Last modification date: 2011-07-13)

• Primary citation: Oliver, A.W.,Swift, S.,Lord, C.J.,Ashworth, A.,Pearl, L.H.; Structural Basis for Recruitment of Brca2 by Palb2; Embo Rep., 10:990-, 2009; PubMed: 19609323; DOI: 10.1038/EMBOR.2009.126

Experimental method

X-RAY DIFFRACTION (1.9 Å)