1NWY
 
 | | COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS WITH AZITHROMYCIN | | 分子名称: | 23S RIBOSOMAL RRNA, 5S RIBOSOMAL RRNA, AZITHROMYCIN, ... | | 著者 | Schluenzen, F, Harms, J, Franceschi, F, Hansen, H.A.S, Bartels, H, Zarivach, R, Yonath, A. | | 登録日 | 2003-02-07 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for the antibiotic activity of ketolides and azalides.
Structure, 11, 2003
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1OAA
 | | MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, SEPIAPTERIN REDUCTASE, ... | | 著者 | Auerbach, G, Herrmann, A, Bacher, A, Huber, R. | | 登録日 | 1997-08-25 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters.
EMBO J., 16, 1997
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1O3Q
 | | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | | 登録日 | 2003-03-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
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1O45
 | | CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU84687. | | 分子名称: | N-ACETYL-N-[1-(1,1'-BIPHENYL-4-YLMETHYL)-2-OXOAZEPAN-3-YL]-3-FORMYL-O-PHOSPHONOTYROSINAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | | 著者 | Lange, G, Loenze, P, Liesum, A. | | 登録日 | 2003-06-15 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
J.Med.Chem., 46, 2003
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1O4F
 | | CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU79073. | | 分子名称: | 1,2,3,4-TETRAHYDROQUINOLIN-8-YL DIHYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | | 著者 | Lange, G, Loenze, P, Liesum, A. | | 登録日 | 2003-06-15 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
J.Med.Chem., 46, 2003
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1O4K
 | | CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH PASBN. | | 分子名称: | BENZYL 2-FORMYLPHENYL HYDROGEN PHOSPHATE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | | 著者 | Lange, G, Loenze, P, Liesum, A. | | 登録日 | 2003-06-15 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
J.Med.Chem., 46, 2003
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1O0R
 | | Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... | | 著者 | Ramakrishnan, B, Balaji, P.V, Qasba, P.K. | | 登録日 | 2003-02-24 | | 公開日 | 2003-03-04 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF BETA 1,4-GALACTOSYLTRANSFERASE COMPLEX WITH UDP-GAL
REVEALS AN OLIGOSACCHARIDE ACCEPTOR BINDING SITE
J.Mol.Biol., 318, 2002
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1O7Z
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1O13
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1O9W
 | | F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17A-G FIMBRIAL ADHESIN | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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1O4J
 | | CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH ISO24. | | 分子名称: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, [(4-ETHYLPHENYL)AMINO]CARBONYLPHOSPHONIC ACID | | 著者 | Lange, G, Loenze, P, Liesum, A. | | 登録日 | 2003-06-15 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
J.Med.Chem., 46, 2003
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1OF0
 | | CRYSTAL STRUCTURE OF BACILLUS SUBTILIS COTA AFTER 1H SOAKING WITH ABTS | | 分子名称: | 3-ETHYL-2-[(2Z)-2-(3-ETHYL-6-SULFO-1,3-BENZOTHIAZOL-2(3H)-YLIDENE)HYDRAZINO]-6-SULFO-3H-1,3-BENZOTHIAZOL-1-IUM, COPPER (I) ION, CU-O LINKAGE, ... | | 著者 | Enguita, F.J, Marcal, D, Grenha, R, Martins, L.O, Henriques, A.O, Carrondo, M.A. | | 登録日 | 2003-04-03 | | 公開日 | 2004-05-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural Characterization of a Bacterial Laccase Reaction Cycle
To be Published
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1P93
 | | CRYSTAL STRUCTURE OF THE AGONIST FORM OF GLUCOCORTICOID RECEPTOR | | 分子名称: | DEXAMETHASONE, Glucocorticoid receptor, Nuclear receptor coactivator 2 | | 著者 | Kauppi, B, Jakob, C, Farnegardh, M, Yang, J, Ahola, H, Alarcon, M, Calles, K, Engstrom, O, Harlan, J, Muchmore, S, Ramqvist, A.-K, Thorell, S, Ohman, L, Greer, J, Gustafsson, J.-A, Carlstedt-Duke, J, Carlquist, M. | | 登録日 | 2003-05-09 | | 公開日 | 2003-07-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain:
RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM.
J.Biol.Chem., 278, 2003
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1OIB
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1OPD
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1OSJ
 | | STRUCTURE OF 3-ISOPROPYLMALATE DEHYDROGENASE | | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE | | 著者 | Qu, C, Akanuma, S, Moriyama, H, Tanaka, N, Oshima, T. | | 登録日 | 1996-10-22 | | 公開日 | 1997-01-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A mutation at the interface between domains causes rearrangement of domains in 3-isopropylmalate dehydrogenase.
Protein Eng., 10, 1997
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1P39
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1OSM
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1OXM
 | | STRUCTURE OF CUTINASE | | 分子名称: | BUTYL-PHOSPHINIC ACID 2,3-BIS-BUTYLCARBAMOYLOXY-PROPYL ESTER GROUP, CUTINASE | | 著者 | Longhi, S, Cambillau, C. | | 登録日 | 1996-10-26 | | 公開日 | 1997-05-15 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of cutinase covalently inhibited by a triglyceride analogue.
Protein Sci., 6, 1997
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1ORK
 | | TET REPRESSOR, CLASS D IN COMPLEX WITH 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEMETHYL-6-DEOXY-TETRACYCLINE | | 分子名称: | 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEOXY-6-DEMETHYL-TETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR | | 著者 | Orth, P, Schnappinger, D, Sum, P.-E, Ellestad, G.A, Hillen, W, Saenger, W, Hinrichs, W. | | 登録日 | 1998-05-21 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.
J.Mol.Biol., 285, 1999
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1OL6
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1OHB
 | | Acetylglutamate kinase from Escherichia coli complexed with ADP and sulphate | | 分子名称: | ACETATE ION, ACETYLGLUTAMATE KINASE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gil-Ortiz, F, Ramon-Maiques, S, Fita, I, Rubio, V. | | 登録日 | 2003-05-23 | | 公開日 | 2003-07-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined from the Structures of Crystalline Complexes, Including a Complex with an Alf(4)(-) Transition State Mimic
J.Mol.Biol., 331, 2003
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1OG3
 | | Crystal structure of the eukaryotic mono-ADP-ribosyltransferase ART2.2 mutant E189I in complex with NAD | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 2 | | 著者 | Ritter, H, Koch-Nolte, F, Marquez, V.E, Schulz, G.E. | | 登録日 | 2003-04-24 | | 公開日 | 2003-08-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Substrate Binding and Catalysis of Ecto-Adp-Ribosyltransferase 2.2 From Rat
Biochemistry, 42, 2003
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1OKZ
 | | Structure of human PDK1 kinase domain in complex with UCN-01 | | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, 7-HYDROXYSTAUROSPORINE, GLYCEROL, ... | | 著者 | Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2003-08-01 | | 公開日 | 2004-07-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition
Biochem.J., 375, 2003
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1OIW
 | | X-ray structure of the small G protein Rab11a in complex with GTPgammaS | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, RAS-RELATED PROTEIN RAB-11A | | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | | 登録日 | 2003-06-26 | | 公開日 | 2004-01-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes
J.Biol.Chem., 279, 2004
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