7JPR
 
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6BZH
 | | Structure of mouse RIG-I tandem CARDs | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58 | | 著者 | Kershaw, N.J, D'Cruz, A.A, Babon, J.J, Nicholson, S.E. | | 登録日 | 2017-12-24 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification of a second binding site on the TRIM25 B30.2 domain.
Biochem. J., 475, 2018
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7ZSC
 | | Crystal structure of the heterodimeric human C-P4H-II with truncated alpha subunit (C-P4H-II delta281) | | 分子名称: | Prolyl 4-hydroxylase subunit alpha-2, Protein disulfide-isomerase, SULFATE ION | | 著者 | Lebedev, A, Koski, M.K, Wierenga, R.K, Murthy, A.V, Sulu, R. | | 登録日 | 2022-05-06 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H alpha 2 beta 2 tetramer.
J.Biol.Chem., 298, 2022
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6WWC
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7ANZ
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6BMX
 | | Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor SHP844 | | 分子名称: | 1-(3-chloro-4-{[1-(2-hydroxy-3-methoxyphenyl)-5-oxo[1,2,4]triazolo[4,3-a]quinazolin-4(5H)-yl]methyl}benzene-1-carbonyl)-L-proline, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Stams, T, Fodor, M. | | 登録日 | 2017-11-15 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.424 Å) | | 主引用文献 | Dual Allosteric Inhibition of SHP2 Phosphatase.
ACS Chem. Biol., 13, 2018
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5JJR
 | | Dengue 3 NS5 protein with compound 29 | | 分子名称: | 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Lescar, J, El Sahili, A. | | 登録日 | 2016-04-25 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
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7JSX
 | | EPYC1(106-135) peptide-bound Rubisco | | 分子名称: | EPYC1, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain 2, ... | | 著者 | Matthies, D, He, S, Jonikas, M.C. | | 登録日 | 2020-08-16 | | 公開日 | 2020-11-18 | | 最終更新日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (2.06 Å) | | 主引用文献 | The structural basis of Rubisco phase separation in the pyrenoid.
Nat.Plants, 6, 2020
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7ZQ9
 | | Dimeric PSI of Chlamydomonas reinhardtii at 2.74 A resolution (symmetry expanded) | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Naschberger, A, Amunts, A. | | 登録日 | 2022-04-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex.
Nat.Plants, 8, 2022
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6WWA
 | | Crystal structure of human SHLD2-SHLD3-REV7 complex | | 分子名称: | Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 2,Shieldin complex subunit 3 chimera | | 著者 | Xie, W, Patel, D.J. | | 登録日 | 2020-05-08 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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1AUC
 | | HUMAN THIOREDOXIN (OXIDIZED WITH DIAMIDE) | | 分子名称: | THIOREDOXIN | | 著者 | Anderson, J.F, Sanders, D.A.R, Gasdaska, J, Weichsel, A, Powis, G, Montfort, W.R. | | 登録日 | 1997-08-22 | | 公開日 | 1998-02-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Biochemistry, 36, 1997
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6C16
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6X46
 | | NMR solution structure of Asterix/Gtsf1 from mouse (CHHC zinc finger domains) | | 分子名称: | Gametocyte-specific factor 1, ZINC ION | | 著者 | Ipsaro, J.J, O'Brien, P.A, Bhattacharya, S, Palmer III, A.G, Joshua-Tor, L. | | 登録日 | 2020-05-22 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons.
Cell Rep, 34, 2021
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5LP4
 | | Penicillin-Binding Protein (PBP2) from Helicobacter pylori | | 分子名称: | Penicillin-binding protein 2 (Pbp2), SULFATE ION | | 著者 | Contreras-Martel, C, Martins, A, Ecobichon, C, Maragno, D.M, Mattei, P.J, El Ghachi, M, Boneca, I.G, Dessen, A. | | 登録日 | 2016-08-11 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Molecular architecture of the PBP2-MreC core bacterial cell wall synthesis complex.
Nat Commun, 8, 2017
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5JJS
 | | Dengue 3 NS5 protein with compound 27 | | 分子名称: | 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-{[(1R,3R)-3-methoxycyclohexyl]sulfonyl}benzamide, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Lescar, J, El Sahili, A. | | 登録日 | 2016-04-25 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Plos Pathog., 12, 2016
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1GUS
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6WW9
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5JMO
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7AOI
 | | Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate | | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | | 著者 | Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. | | 登録日 | 2020-10-14 | | 公開日 | 2020-12-02 | | 最終更新日 | 2021-03-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
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5LQZ
 | | Structure of F-ATPase from Pichia angusta, state1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ... | | 著者 | Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. | | 登録日 | 2016-08-17 | | 公開日 | 2016-11-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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7ZQC
 | | Monomeric PSI of Chlamydomonas reinhardtii at 2.31 A resolution | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Naschberger, A, Amunts, A. | | 登録日 | 2022-04-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.31 Å) | | 主引用文献 | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex.
Nat.Plants, 8, 2022
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6SPJ
 | | A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 1 | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Chantadul, V, Amporndanai, K, Wright, G, Antonyuk, S, Hasnain, S. | | 登録日 | 2019-09-01 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy.
Commun Biol, 3, 2020
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7ZQE
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6O0M
 | | crystal structure of BCL-2 F104L mutation with venetoclax | | 分子名称: | 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-[(3-nitro-4-{[(oxan-4-yl )methyl]amino}phenyl)sulfonyl]-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2, DI(HYDROXYETHYL)ETHER | | 著者 | Birkinshaw, R.W, Luo, C.S, Colman, P.M, Czabotar, P.E. | | 登録日 | 2019-02-16 | | 公開日 | 2019-05-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Nat Commun, 10, 2019
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7ZQD
 | | Dimeric PSI of Chlamydomonas reinhardtii at 2.97 A resolution | | 分子名称: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | | 著者 | Naschberger, A, Amunts, A. | | 登録日 | 2022-04-29 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Algal photosystem I dimer and high-resolution model of PSI-plastocyanin complex.
Nat.Plants, 8, 2022
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