PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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4LX5	X-ray crystal structure of the M6" riboswitch aptamer bound to pyrimido[4,5-d]pyrimidine-2,4-diamine (PPDA) 分子名称: MAGNESIUM ION, Mutated adenine riboswitch aptamer, pyrimido[4,5-d]pyrimidine-2,4-diamine 著者 Dunstan, M.S, Leys, D. 登録日 2013-07-29 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Modular riboswitch toolsets for synthetic genetic control in diverse bacterial species. J.Am.Chem.Soc., 136, 2014
4EAI	Co-crystal structure of an AMPK core with AMP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.285 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4E48	Structure of 20mer double-helical RNA composed of CUG/CUG-repeats 分子名称: 5'-R(P*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*C)-3', POTASSIUM ION, SULFATE ION 著者 Katorcha, E, Malinina, L. 登録日 2012-03-12 公開日 2012-07-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural dynamics of double-helical RNAs composed of CUG/CUG- and CUG/CGG-repeats. J.Biomol.Struct.Dyn., 30, 2012
4M06	Crystal Structure of Mutant Chlorite Dismutase from Candidatus Nitrospira defluvii W145F in Complex with Cyanide 分子名称: 1,2-ETHANEDIOL, CYANIDE ION, Chlorite dismutase, ... 著者 Hagmueller, A, Gysel, K, Djinovic-Carugo, K. 登録日 2013-08-01 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity. Biochemistry, 53, 2014
4EMY	Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. 分子名称: Aminotransferase class I and II, PYRIDOXAL-5'-PHOSPHATE 著者 Chang, C, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-04-12 公開日 2012-05-09 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Crystal structure of aminotransferase from anaerococcus prevotii dsm 20548. TO BE PUBLISHED
4EAK	Co-crystal structure of an AMPK core with ATP 分子名称: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... 著者 Chen, L, Wang, J, Zhang, Y.-Y, Yan, S.F, Neumann, D, Schlattner, U, Wang, Z.-X, Wu, J.-W. 登録日 2012-03-22 公開日 2012-06-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 AMP-activated protein kinase undergoes nucleotide-dependent conformational changes Nat.Struct.Mol.Biol., 19, 2012
4ESK	Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 (NYSGRC-006047)IG-like domain 分子名称: GLYCEROL, Leukocyte-associated immunoglobulin-like receptor 1, POTASSIUM ION, ... 著者 Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) 登録日 2012-04-23 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 IG-like domain to be published
7AAZ	Crystal structure of MerTK in complex with a type 1.5 aminopyridine inhibitor 分子名称: 1,2-ETHANEDIOL, 2-azanyl-~{N}-[(1~{S},2~{S})-2-[[4-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]methoxy]cyclopentyl]-5-(1-methylpyrazol-4-yl)pyridine-3-carboxamide, CHLORIDE ION, ... 著者 Pflug, A, Schimpl, M, McCoull, W, Nissink, J.W.M, Overman, R.C, Rawlins, P.B, Truman, C, Underwood, E, Warwicker, J, Winter-Holt, J. 登録日 2020-09-05 公開日 2020-11-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.855 Å) 主引用文献 A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding. Biochem.J., 477, 2020
4EW1	High resolution structure of human glycinamide ribonucleotide transformylase in apo form. 分子名称: PHOSPHATE ION, SULFATE ION, Trifunctional purine biosynthetic protein adenosine-3 著者 Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. 登録日 2012-04-26 公開日 2013-07-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.522 Å) 主引用文献 Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
4LKO	Crystal structure of human DPP-IV in complex with BMS-744891 分子名称: 3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, Dipeptidyl peptidase 4 著者 Klei, H.E. 登録日 2013-07-08 公開日 2013-09-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J.Med.Chem., 56, 2013
4EY3	Crystal structure of solute binding protein of ABC transporter in complex with p-hydroxybenzoic acid 分子名称: P-HYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal 著者 Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-05-01 公開日 2012-05-30 最終更新日 2012-10-24 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
4LML	GLIC double mutant I9'A T25'A 分子名称: Proton-gated ion channel 著者 Grosman, C, Gonzalez-Gutierrez, G. 登録日 2013-07-10 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proc.Natl.Acad.Sci.USA, 110, 2013
6ZRT	Crystal structure of SARS CoV2 main protease in complex with inhibitor Telaprevir 分子名称: (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, DIMETHYL SULFOXIDE, Main Protease 著者 Oerlemans, R, Wang, W, Lunev, S, Domling, A, Groves, M.R. 登録日 2020-07-14 公開日 2020-08-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Repurposing the HCV NS3-4A protease drug boceprevir as COVID-19 therapeutics. Rsc Med Chem, 12, 2020
7TTM	Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat SHC014 receptor-binding domain 分子名称: 1040 heavy chain, 1040 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Reddem, E.R, Shapiro, L. 登録日 2022-02-01 公開日 2022-04-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
4M09	Crystal Structure of Mutant Chlorite Dismutase from Candidatus Nitrospira defluvii W146Y R173Q 分子名称: 1,2-ETHANEDIOL, Chlorite dismutase, IMIDAZOLE, ... 著者 Gysel, K, Hagmueller, A, Djinovic-Carugo, K. 登録日 2013-08-01 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Manipulating conserved heme cavity residues of chlorite dismutase: effect on structure, redox chemistry, and reactivity. Biochemistry, 53, 2014
4M7S	Crystal structure of SeMet BtrN in an OPEN conformation 分子名称: BtrN, GLYCEROL, IMIDAZOLE, ... 著者 Goldman, P.J, Drennan, C.L. 登録日 2013-08-12 公開日 2013-10-02 最終更新日 2014-02-05 実験手法 X-RAY DIFFRACTION (2.022 Å) 主引用文献 X-ray analysis of butirosin biosynthetic enzyme BtrN redefines structural motifs for AdoMet radical chemistry. Proc.Natl.Acad.Sci.USA, 110, 2013
4LNY	Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 分子名称: CADMIUM ION, CHLORIDE ION, Engineered Protein OR422 著者 Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Sahdev, S, Xiao, R, Maglaqui, M, Kogan, S, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2013-07-12 公開日 2013-08-07 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.929 Å) 主引用文献 Crystal Structure of Engineered Protein OR422. To be Published
4LLL	Crystal structure of S. aureus MepR-DNA complex 分子名称: MepR, Palindromized mepR operator sequence 著者 Birukou, I, Brennan, R.G. 登録日 2013-07-09 公開日 2014-05-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.036 Å) 主引用文献 Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Res., 42, 2014
4LCO	Crystal structure of NE0047 with complex with substrate ammeline 分子名称: 4,6-diamino-1,3,5-triazin-2-ol, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Bitra, A, Biswas, A, Anand, R. 登録日 2013-06-22 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
4LCP	Crytsal structure of NE0047 in complex with 2,6-diaminopurine 分子名称: 9H-PURINE-2,6-DIAMINE, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Bitra, A, Biswas, A, Anand, R. 登録日 2013-06-22 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
7OYF	Crystal structure of depupylase Dop in complex with Pup and ADP/trifluoromagnesate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Cui, H. 登録日 2021-06-24 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation. Nat Commun, 12, 2021
7OYH	Crystal structure of depupylase Dop in complex with Pup and ADP/tetrafluoromagnesate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Cui, H. 登録日 2021-06-24 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation. Nat Commun, 12, 2021
4L5W	Structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 Boone, C.D, Gill, S, McKenna, R. 登録日 2013-06-11 公開日 2014-04-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II. Arch.Biochem.Biophys., 539, 2013
4L7W	Crystal structure mutant H77A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 分子名称: HD domain-containing protein 2, MAGNESIUM ION 著者 Kuzin, A, Su, M, Yakunin, A, Beloglazova, N, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Brown, G, Flick, R, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2013-06-14 公開日 2013-07-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 Northeast Structural Genomics Consortium Target HR6723 To be Published
7TJC	VHH Chl-B2 in complex with Chloramphenicol 分子名称: CHLORAMPHENICOL, GLYCEROL, VHH-Chl-B2 著者 Nordeen, S.A, Schwartz, T.U. 登録日 2022-01-16 公開日 2022-11-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure and specificity of an anti-chloramphenicol single domain antibody for detection of amphenicol residues. Protein Sci., 31, 2022

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