4NM2
 
 | | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position | | 分子名称: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | 著者 | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | 登録日 | 2013-11-14 | | 公開日 | 2014-01-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.524 Å) | | 主引用文献 | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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4NLD
 | | Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase complex with BMS-791325 also known as (1aR,12bS)-8-cyclohexyl-n-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide and 2-(4-fluorophenyl)-n-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide | | 分子名称: | (1aR,12bS)-8-cyclohexyl-N-(dimethylsulfamoyl)-11-methoxy-1a-{[(1R,5S)-3-methyl-3,8-diazabicyclo[3.2.1]oct-8-yl]carbonyl}-1,1a,2,12b-tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide, 2-(4-fluorophenyl)-N-methyl-6-[(methylsulfonyl)amino]-5-(propan-2-yloxy)-1-benzofuran-3-carboxamide, RNA-directed RNA polymerase, ... | | 著者 | Sheriff, S. | | 登録日 | 2013-11-14 | | 公開日 | 2014-03-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Discovery and Preclinical Characterization of the Cyclopropylindolobenzazepine BMS-791325, A Potent Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase.
J.Med.Chem., 57, 2014
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1MKH
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5XK1
 | | Structure of 8-mer DNA3 | | 分子名称: | DNA (5'-D(*GP*GP*AP*GP*CP*CP*CP*C)-3') | | 著者 | Liu, H.H, Gan, J.H. | | 登録日 | 2017-05-04 | | 公開日 | 2017-12-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs.
Angew. Chem. Int. Ed. Engl., 56, 2017
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3CU8
 | | Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome | | 分子名称: | 14-3-3 protein zeta/delta, MAGNESIUM ION, PROPANOIC ACID, ... | | 著者 | Schumacher, B, Weyand, M, Kuhlmann, J, Ottmann, C. | | 登録日 | 2008-04-16 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol. Cell. Biol., 30, 2010
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2IKK
 | | Structural Genomics, the crystal structure of the C-terminal domain of Yurk from Bacillus subtilis subsp. subtilis str. 168 | | 分子名称: | Hypothetical transcriptional regulator yurK, SULFATE ION | | 著者 | Tan, K, Hatzos, C, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-10-02 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of the C-terminal domain of Yurk from Bacillus subtilis subsp. subtilis str. 168
To be Published
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7L0O
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2CCP
 | | X-RAY STRUCTURES OF RECOMBINANT YEAST CYTOCHROME C PEROXIDASE AND THREE HEME-CLEFT MUTANTS PREPARED BY SITE-DIRECTED MUTAGENESIS | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, YEAST CYTOCHROME C PEROXIDASE | | 著者 | Wang, J, Mauro, J.M, Edwards, S.L, Oatley, S.J, Fishel, L.A, Ashford, V.A, Xuong, N.-H, Kraut, J. | | 登録日 | 1990-02-28 | | 公開日 | 1991-07-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | X-ray structures of recombinant yeast cytochrome c peroxidase and three heme-cleft mutants prepared by site-directed mutagenesis.
Biochemistry, 29, 1990
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2CXB
 | | CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS | | 分子名称: | CYTOCHROME C2, HEME C | | 著者 | Axelrod, H.L, Feher, G, Allen, J.P, Chirino, A.J, Day, M.W, Hsu, B.T, Rees, D.C. | | 登録日 | 1994-04-21 | | 公開日 | 1995-10-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystallization and X-ray structure determination of cytochrome c2 from Rhodobacter sphaeroides in three crystal forms.
Acta Crystallogr.,Sect.D, 50, 1994
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1XXE
 | | RDC refined solution structure of the AaLpxC/TU-514 complex | | 分子名称: | 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION | | 著者 | Coggins, B.E, McClerren, A.L, Jiang, L, Li, X, Rudolph, J, Hindsgaul, O, Raetz, C.R.H, Zhou, P. | | 登録日 | 2004-11-04 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Refined Solution Structure of the LpxC-TU-514 Complex and pK(a) Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design
Biochemistry, 44, 2005
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1Z60
 | | Solution structure of the carboxy-terminal domain of human TFIIH P44 subunit | | 分子名称: | TFIIH basal transcription factor complex p44 subunit, ZINC ION | | 著者 | Kellenberger, E, Dominguez, C, Fribourg, S, Wasielewski, E, Moras, D, Poterszman, A, Boelens, R, Kieffer, B. | | 登録日 | 2005-03-21 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions.
J.Biol.Chem., 280, 2005
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2KSC
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1FI3
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4CG4
 | | Crystal structure of the CHS-B30.2 domains of TRIM20 | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, PYRIN, ... | | 著者 | Weinert, C, Morger, D, Djekic, A, Mittl, P.R.E, Gruetter, M.G. | | 登録日 | 2013-11-20 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of Trim20 C-Terminal Coiled-Coil/B30.2 Fragment: Implications for the Recognition of Higher Order Oligomers
Sci.Rep., 5, 2015
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3IA8
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3IGN
 | | Crystal Structure of the GGDEF domain from Marinobacter aquaeolei diguanylate cyclase complexed with c-di-GMP - Northeast Structural Genomics Consortium Target MqR89a | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Diguanylate cyclase | | 著者 | Vorobiev, S, Neely, H, Seetharaman, J, Wang, H, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2009-07-28 | | 公開日 | 2009-08-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product.
J.Struct.Funct.Genom., 13, 2012
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3IW4
 | | Crystal structure of PKC alpha in complex with NVP-AEB071 | | 分子名称: | 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione, Protein kinase C alpha type | | 著者 | Stark, W, Rummel, G, Strauss, A, Cowan-Jacob, S.W. | | 登録日 | 2009-09-02 | | 公開日 | 2009-11-03 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes
J.Med.Chem., 52, 2009
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5MVO
 | | FoxE P43212 crystal structure of Rhodopseudomonas ferrooxidans SW2 putative iron oxidase | | 分子名称: | COPPER (II) ION, FoxE, HEME C, ... | | 著者 | Pereira, L, Saraiva, I.H, Oliveira, A.S, Soares, C, Gomes, R.O, Frazao, C. | | 登録日 | 2017-01-17 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.668 Å) | | 主引用文献 | Crystallization and preliminary crystallographic studies of FoxE from Rhodobacter ferrooxidans SW2, an Fe(II) oxidoreductase involved in photoferrotrophy.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 68, 2012
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6WIF
 | | Class C beta-lactamase from Acinetobacter baumannii in complex with 4-(Ethyl(methyl)carbamoyl)phenyl boronic acid | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase, ... | | 著者 | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-04-09 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | class C beta-lactamase from Acinetobacter baumannii in complex with 4-(Ethyl(methyl)carbamoyl)phenyl boronic acid
To Be Published
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3BGE
 | | Crystal structure of the C-terminal fragment of AAA+ATPase from Haemophilus influenzae | | 分子名称: | Predicted ATPase, SULFATE ION | | 著者 | Ramagopal, U.A, Patskovsky, Y, Bonanno, J.B, Meyer, A.J, Toro, R, Freeman, J, Adams, J, Koss, J, Maletic, M, Gheyi, T, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2007-11-26 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of the C-terminal fragment of AAA+ATPase from Haemophilus influenzae.
To be Published
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2K90
 | | Dimeric solution structure of the DNA loop d(TGCTTCGT) | | 分子名称: | 5'-D(*TP*GP*CP*TP*TP*CP*GP*T)-3' | | 著者 | Viladoms, J, Escaja, N, Frieden, M, Gomez-Pinto, I, Pedroso, E, Gonzalez, C. | | 登録日 | 2008-09-29 | | 公開日 | 2009-04-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Self-association of short DNA loops through minor groove C:G:G:C tetrads.
Nucleic Acids Res., 37, 2009
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1M1R
 | | Reduced p222 crystal structure of the tetraheme cytochrome c of Shewanella oneidensis MR1 | | 分子名称: | HEME C, SMALL tetraheme cytochrome c, SULFATE ION | | 著者 | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | | 登録日 | 2002-06-20 | | 公開日 | 2002-08-14 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | | 主引用文献 | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c
J.Biol.Chem., 277, 2002
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2K97
 | | Dimeric solution structure of the cyclic octamer d(pCGCTCCGT) | | 分子名称: | 5'-D(P*CP*GP*CP*TP*CP*CP*GP*T)-3' | | 著者 | Viladoms, J, Escaja, N, Frieden, M, Gomez-Pinto, I, Pedroso, E, Gonzalez, C. | | 登録日 | 2008-09-30 | | 公開日 | 2009-04-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Self-association of short DNA loops through minor groove C:G:G:C tetrads.
Nucleic Acids Res., 37, 2009
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3PDF
 | | Discovery of Novel Cyanamide-Based Inhibitors of Cathepsin C | | 分子名称: | 2,5-dibromo-N-{(3R,5S)-1-[(Z)-iminomethyl]-5-methylpyrrolidin-3-yl}benzenesulfonamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhao, B, Laine, D. | | 登録日 | 2010-10-22 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Discovery of novel cyanamide-based inhibitors of cathepsin C.
Acs Med.Chem.Lett., 2, 2011
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2XL6
 | | Cytochrome c prime from Alcaligenes xylosoxidans: Ferrous R124A variant with bound NO | | 分子名称: | CYTOCHROME C', HEME C, NITRATE ION, ... | | 著者 | Hough, M.A, Antonyuk, S.V, Hasnain, S.S. | | 登録日 | 2010-07-19 | | 公開日 | 2010-11-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Distal-to-Proximal No Conversion in Hemoproteins: The Role of the Proximal Pocket.
J.Mol.Biol., 405, 2011
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