PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7YP9	Cryo-EM structure of Escherichia coli paused complex of transcription termination (TTC-pause) 分子名称: DNA (31-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 You, L.L, Zhang, Y. 登録日 2022-08-03 公開日 2022-11-16 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis for intrinsic transcription termination. Nature, 613, 2023
7Z03	Endonuclease state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and extended dsDNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (39-MER), MAGNESIUM ION, ... 著者 Gut, F, Kaeshammer, L, Lammens, K, Bartho, J, van de Logt, E, Kessler, B, Hopfner, K.P. 登録日 2022-02-21 公開日 2022-08-17 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50. Mol.Cell, 82, 2022
7YZO	Endonuclease state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and dsDNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (31-MER), MAGNESIUM ION, ... 著者 Gut, F, Kaeshammer, L, Lammens, K, Bartho, J, van de Logt, E, Kessler, B, Hopfner, K.P. 登録日 2022-02-21 公開日 2022-08-17 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50. Mol.Cell, 82, 2022
7PLQ	Crystal structure of the PARP domain of wheat SRO1 分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ... 著者 Wirthmueller, L, Loll, B. 登録日 2021-09-01 公開日 2021-10-27 最終更新日 2022-11-09 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 The superior salinity tolerance of bread wheat cultivar Shanrong No. 3 is unlikely to be caused by elevated Ta-sro1 poly-(ADP-ribose) polymerase activity. Plant Cell, 34, 2022
6D6K	Structure of polyribonucleotide nucleotidyltransferase from Acinetobacter baumannii 分子名称: Polyribonucleotide nucleotidyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-04-21 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of polyribonucleotide nucleotidyltransferase from Acinetobacter baumannii to be published
7Q2U	The crystal structure of the HINT1 Q62A mutant. 分子名称: CACODYLATE ION, HEXAETHYLENE GLYCOL, Histidine triad nucleotide-binding protein 1, ... 著者 Dolot, R.M, Strom, A.M, Wagner, C.R. 登録日 2021-10-26 公開日 2021-11-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. Biochemistry, 61, 2022
7VCI	Structure of Xenopus laevis NPC nuclear ring asymmetric unit 分子名称: GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ... 著者 Tai, L, Zhu, Y, Sun, F. 登録日 2021-09-03 公開日 2022-02-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (8.1 Å) 主引用文献 8 angstrom structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI. Protein Cell, 13, 2022
6D9C	Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-glucose (open, reduced) 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SODIUM ION, UDP-galactopyranose mutase, ... 著者 Wangkanont, K, Kiessling, L.L, Forest, K.T. 登録日 2018-04-28 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Substrate recognition by FAD in UDP-galactopyranose mutase To be published
6DOG	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 600 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.285 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DOU	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 5 mM Mg2+ and 200 mM Rb+ for 120 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DP7	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 500 mM Mn2+ and 200 mM K+ for 40 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), IODIDE ION, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.381 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DPN	Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.493 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6DAS	Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design 分子名称: N-[(1R)-6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-2,3-dihydro-1H-inden-1-yl]-3-methoxy-4-methylbenzamide, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-05-01 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. J. Med. Chem., 61, 2018
6DQA	Linked KDM5A JMJ Domain Bound to Inhibitor N70 i.e.[2-((3-aminophenyl)(2-(piperidin-1-yl)ethoxy)methyl)thieno[3,2-b]pyridine-7-carboxylic acid] 分子名称: 1,2-ETHANEDIOL, 2-{(R)-(3-aminophenyl)[2-(piperidin-1-yl)ethoxy]methyl}thieno[3,2-b]pyridine-7-carboxylic acid, GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2018-06-10 公開日 2018-11-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.888 Å) 主引用文献 Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A. J. Med. Chem., 61, 2018
7VBV	Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 7 分子名称: ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Orita, T, Doi, S, Iwanaga, T, Fujishima, A, Adachi, T. 登録日 2021-09-01 公開日 2022-02-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors. Bioorg.Med.Chem., 52, 2021
6DEF	Vps1 GTPase-BSE fusion complexed with GMPPCP 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Vps1 GTPase-BSE 著者 Ford, M.G.J, Varlakhanova, N.V, Brady, T.M, Chappie, J.S, Hosford, C.J. 登録日 2018-05-11 公開日 2018-08-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
6DID	HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B. 登録日 2018-05-23 公開日 2018-09-05 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.71 Å) 主引用文献 Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity, 49, 2018
7PRP	Crystal Structure of the B subunit of heat labile enterotoxin LT-IIc from Escherichia coli in apo form 分子名称: FORMIC ACID, Heat-labile enterotoxin IIA, B chain, ... 著者 Varrot, A. 登録日 2021-09-22 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc. Glycobiology, 32, 2022
7PFK	20 minute Fe2+ soaked structure of SynFtn variant E141D 分子名称: CHLORIDE ION, FE (III) ION, Ferritin 著者 Hemmings, A.M, Bradley, J.M. 登録日 2021-08-11 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Key carboxylate residues for iron transit through the prokaryotic ferritin Syn Ftn. Microbiology (Reading, Engl.), 167, 2021
6DM0	Open state GluA2 in complex with STZ and blocked by IEM-1460, after micelle signal subtraction 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... 著者 Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. 登録日 2018-06-04 公開日 2018-08-22 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
7PFH	2 minute Fe2+ soak structure of SynFtn E141D 分子名称: ACETATE ION, CHLORIDE ION, FE (III) ION, ... 著者 Hemmings, A.M, Bradley, J.M. 登録日 2021-08-11 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Key carboxylate residues for iron transit through the prokaryotic ferritin Syn Ftn. Microbiology (Reading, Engl.), 167, 2021
7PTY	Delta-latroinsectotoxin dimer 分子名称: Delta-latroinsectotoxin-Lt1a 著者 Chen, M, Gatsogiannis, C. 登録日 2021-09-27 公開日 2021-12-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Molecular architecture of black widow spider neurotoxins. Nat Commun, 12, 2021
6DPD	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 16 mM Mn2+ and 200 mM K+ for 40 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7PF9	SynFtn Variant E141D 分子名称: CHLORIDE ION, Ferritin, SODIUM ION 著者 Hemmings, A.M, Bradley, J.M. 登録日 2021-08-11 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Key carboxylate residues for iron transit through the prokaryotic ferritin Syn Ftn. Microbiology (Reading, Engl.), 167, 2021
6DQC	LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N50 i.e. 2-(4-((2-(dimethylamino)ethyl)(ethyl)carbamoyl)-5-(4-methoxyphenyl)-1H-pyrazol-1-yl)isonicotinic acid 分子名称: 2-[4-{[2-(dimethylamino)ethyl](ethyl)carbamoyl}-5-(4-methoxyphenyl)-1H-pyrazol-1-yl]pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2018-06-10 公開日 2019-06-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 To be determined To Be Published

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