7Z03

Endonuclease state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and extended dsDNA

Summary for 7Z03

Entry DOI	10.2210/pdb7z03/pdb
Related	7YZO
EMDB information	14391 14403
Descriptor	Nuclease SbcCD subunit C, Nuclease SbcCD subunit D, DNA (39-MER), ... (7 entities in total)
Functional Keywords	abc-type atpase, nuclease, dna repair, dna binding protein
Biological source	Escherichia coli More
Total number of polymer chains	6
Total formula weight	404176.48
Authors	Gut, F.,Kaeshammer, L.,Lammens, K.,Bartho, J.,van de Logt, E.,Kessler, B.,Hopfner, K.P. (deposition date: 2022-02-21, release date: 2022-08-17, Last modification date: 2022-09-28)
Primary citation	Gut, F.,Kashammer, L.,Lammens, K.,Bartho, J.D.,Boggusch, A.M.,van de Logt, E.,Kessler, B.,Hopfner, K.P. Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50. Mol.Cell, 82:3513-3522.e6, 2022 Cited by PubMed: 35987200 DOI: 10.1016/j.molcel.2022.07.019 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation