PDB: 242 件ウェブページステータス検索Chemie searchBIRD

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4QZE	Mouse Tdt, F401A mutant, in complex with a DSB substrate, C-G base pair 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ... 著者 Gouge, J, Delarue, M. 登録日 2014-07-27 公開日 2015-06-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
4QZI	Mouse Tdt, F401A mutant, in complex with a DSB substrate and Zn2+ 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*TP*TP*TP*TP*GP*GP*G)-3', ... 著者 Gouge, J, Delarue, M. 登録日 2014-07-27 公開日 2015-06-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. Embo J., 34, 2015
3LHJ	Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor. 分子名称: Mitogen-activated protein kinase 14, N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide 著者 Mohr, C, Jordan, S. 登録日 2010-01-22 公開日 2010-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase. J.Med.Chem., 53, 2010
5IIT	Structure of SPX domain of the yeast inorganic polyphophate polymerase Vtc4 crystallized by carrier-driven crystallization in fusion with the macro domain of human histone macroH2A1.1 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... 著者 Wild, R, Hothorn, M. 登録日 2016-03-01 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.134 Å) 主引用文献 Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains. Science, 352, 2016
1YFD	Crystal structure of the Y122H mutant of ribonucleotide reductase R2 protein from E. coli 分子名称: MERCURY (II) ION, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 beta chain 著者 Kolberg, M, Logan, D.T, Bleifuss, G, Poetsch, S, Sjoeberg, B.M, Graeslund, A, Lubitz, W, Lassmann, G, Lendzian, F. 登録日 2004-12-31 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A new tyrosyl radical on Phe208 as ligand to the diiron center in Escherichia coli ribonucleotide reductase, mutant R2-Y122H. Combined x-ray diffraction and EPR/ENDOR studies J.Biol.Chem., 280, 2005
7V2Z	ZIKV NS3helicase in complex with ssRNA and ATP-Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Core protein, MANGANESE (II) ION, ... 著者 Lin, M.M, Yang, H.T. 登録日 2021-08-10 公開日 2022-08-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.10101676 Å) 主引用文献 Structural Basis of Zika Virus Helicase in RNA Unwinding and ATP Hydrolysis. Acs Infect Dis., 8, 2022
7ELH	In situ structure of transcriptional enzyme complex and capsid shell protein of mammalian reovirus at initiation state 分子名称: Lambda 1, Minor core protein mu2, PHOSPHATE ION, ... 著者 Zhou, Z.H, Pan, M. 登録日 2021-04-11 公開日 2021-10-20 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins. Nat Commun, 12, 2021
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 2024
7O7Z	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O81	Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O7Y	Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
7O80	Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. 登録日 2021-04-14 公開日 2021-06-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
6D7N	Crystal structure of the W357R/W399R Importin alpha mutant 分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1 著者 Pedersen, L.C, London, R.E, Gabel, S.A. 登録日 2018-04-25 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
6D7M	Crystal structure of the W184R/W231R Importin alpha mutant 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ... 著者 Pedersen, L.C, London, R.E, Gabel, S.A. 登録日 2018-04-25 公開日 2019-03-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.187 Å) 主引用文献 Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
4I2D	Binary complex of mouse TdT with AMPcPP 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, MAGNESIUM ION, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2B	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2G	Binary complex of mouse TdT with ssDNA 分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', COBALT (II) ION, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2A	Binary complex of mouse TdT with ssDNA in absence of divalent transition metal ion 分子名称: 5'-D(*AP*AP*(BRU)P*AP*A)-3', DNA nucleotidylexotransferase, MAGNESIUM ION, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2J	Binary complex of mouse TdT with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2H	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I27	Ternary complex of mouse TdT with ssDNA and incoming nucleotide 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*AP*AP*AP*AP*T)-3', DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2I	Binary complex of mouse TdT with AP5A 分子名称: BIS(ADENOSINE)-5'-PENTAPHOSPHATE, DNA nucleotidylexotransferase, MAGNESIUM ION, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013
4I2E	Ternary complex of mouse TdT with ssDNA and AMPcPP 分子名称: 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Gouge, J, Delarue, M. 登録日 2012-11-21 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism. J.Mol.Biol., 425, 2013

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