PDB: 1138 件ウェブページステータス検索Chemie searchBIRD

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5KKX	Crystal structure of a TbpB C-lobe mutant from Neisseria meningitidis M982 分子名称: GLYCEROL, TbpB 著者 Calmettes, C, Moraes, T.F. 登録日 2016-06-23 公開日 2017-07-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineered hybrid transferrin binding protein antigens for protection against Neisseria meningitidis to be published
8OF2	Trypanosoma brucei pteridine reductase 1 (TbPTR1) in complex with 2,4,6 triamminopyrimidine (TAP) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Tassone, G, Landi, G, Mangani, S, Pozzi, C. 登録日 2023-03-13 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents. Eur.J.Med.Chem., 264, 2023
3CVL	Structure of Peroxisomal Targeting Signal 1 (PTS1) binding domain of Trypanosoma brucei Peroxin 5 (TbPEX5)complexed to T. brucei Phosphofructokinase (PFK) PTS1 peptide 分子名称: Peroxisome targeting signal 1 receptor PEX5, T. brucei PFK PTS1 peptide Ac-HEELAKL 著者 Sampathkumar, P, Roach, C, Michels, P.A.M, Hol, W.G.J. 登録日 2008-04-18 公開日 2008-06-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural Insights into the recognition of peroxisomal targeting signal 1 by Trypanosoma brucei peroxin 5. J.Mol.Biol., 381, 2008
4XTU	Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor (N-({[(1R,2S,3R,4R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxycyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide) 分子名称: Bifunctional ligase/repressor BirA, N-({[(1R,2S,3R,4R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxycyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide 著者 De la Mora-Rey, T, Finzel, B.C. 登録日 2015-01-24 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6500299 Å) 主引用文献 Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor (N-({[(1R,2S,3R,4R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxycyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide) To be Published
3EIK	double stranded DNA binding protein 分子名称: 1,2-ETHANEDIOL, TATA-box-binding protein 著者 Cui, S, Wollmann, P, Moldt, M, Hopfner, K.-P. 登録日 2008-09-16 公開日 2009-09-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 structural studies of ecTBP To be Published
2Z5O	Complex of Transportin 1 with JKTBP NLS 分子名称: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
5TBP	Crystal Structure of RXR-alpha ligand binding domain complexed with synthetic modulator K8003 分子名称: ACETATE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Aleshin, A.E, Liddington, R.C, Su, Y, Zhang, X. 登録日 2016-09-12 公開日 2017-08-09 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha. Nat Commun, 8, 2017
7TBP	X-ray structure of the HIV-1 myristoylated matrix protein 分子名称: CITRIC ACID, Capsid protein p24, MYRISTIC ACID, ... 著者 Green, T.J, Saad, J.S, Samal, A.B. 登録日 2021-12-22 公開日 2022-06-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Atomic view of the HIV-1 matrix lattice; implications on virus assembly and envelope incorporation. Proc.Natl.Acad.Sci.USA, 119, 2022
6TBP	3C-like protease from Southampton virus complexed with FMOPL000490a. 分子名称: DIMETHYL SULFOXIDE, Genome polyprotein, ~{N}-(2-hydroxyphenyl)-2-phenoxy-ethanamide 著者 Guo, J, Cooper, J.B. 登録日 2019-11-03 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors. J Struct Biol X, 4, 2020
8TBP	HLA-DRB1*15:01 in complex with smith antigen 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Ting, Y.T, Broury, A, Ooi, J. 登録日 2023-06-29 公開日 2024-02-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.12621117 Å) 主引用文献 Smith-specific regulatory T cells halt the progression of lupus nephritis. Nat Commun, 15, 2024
2P6V	Structure of TAFH domain of the human TAF4 subunit of TFIID 分子名称: SULFATE ION, Transcription initiation factor TFIID subunit 4 著者 Wang, X, Truckses, D.M, Takada, S, Matsumura, T, Tanese, N, Jacobson, R.H. 登録日 2007-03-19 公開日 2007-05-15 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators. Proc.Natl.Acad.Sci.Usa, 104, 2007
2MJU	Solution structure of a C terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB) 分子名称: Polypyrimidine tract-binding protein 2 著者 Esteve, V, Blatter, M, Allain, F.H.-T. 登録日 2014-01-16 公開日 2014-02-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB). PeerJ, 2, 2014
4CQ1	Crystal structure of the neuronal isoform of PTB 分子名称: CHLORIDE ION, POLYPYRIMIDINE TRACT-BINDING PROTEIN 2, ZINC ION 著者 Joshi, A, Buckroyd, A.N, Curry, S. 登録日 2014-02-10 公開日 2014-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Solution and Crystal Structures of a C Terminal Fragment of the Neuronal Isoform of the Polypyrimidine Tract Binding Protein (Nptb) Peerj, 2, 2014
4DX8	ICAP1 in complex with KRIT1 N-terminus 分子名称: BROMIDE ION, Integrin beta-1-binding protein 1, Krev interaction trapped protein 1 著者 Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J. 登録日 2012-02-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation. Mol.Cell, 49, 2013
4JIF	Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide 分子名称: Integrin beta-1-binding protein 1, Krev interaction trapped protein 1 著者 Liu, W, Boggon, T.J. 登録日 2013-03-05 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide. Acta Crystallogr.,Sect.F, 69, 2013
8GXS	PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. 登録日 2022-09-21 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (4.16 Å) 主引用文献 Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
8GXQ	PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. 登録日 2022-09-21 公開日 2022-11-02 実験手法 ELECTRON MICROSCOPY (5.04 Å) 主引用文献 Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
6T9I	cryo-EM structure of transcription coactivator SAGA 分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... 著者 Wang, H, Cheung, A, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
4WV6	Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8 分子名称: 1,2-ETHANEDIOL, Importin subunit alpha-1, Transcription initiation factor TFIID subunit 8 著者 Trowitzsch, S. 登録日 2014-11-04 公開日 2015-01-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun, 6, 2015
6T9K	SAGA Core module 分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... 著者 Wang, H, Cheung, A, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
4V1N	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
4V1O	Architecture of the RNA polymerase II-Mediator core transcription initiation complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. 登録日 2014-09-29 公開日 2015-02-04 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9.7 Å) 主引用文献 Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
8WAS	Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. 分子名称: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (6.13 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAP	Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. 分子名称: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-08 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (5.85 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023
8WAN	Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. 分子名称: Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... 著者 Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. 登録日 2023-09-07 公開日 2023-12-06 最終更新日 2024-01-03 実験手法 ELECTRON MICROSCOPY (6.07 Å) 主引用文献 Structural visualization of transcription initiation in action. Science, 382, 2023

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