4LS7
 
 | | Crystal structure of Bacillus subtilis beta-ketoacyl-ACP synthase II (FabF) in a non-covalent complex with cerulenin | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Cerulenin, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.674 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
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4NA2
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4NA3
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4NA1
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4MZ0
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4LS6
 | | Crystal structure of beta-ketoacyl-ACP synthase II (FabF) I108F mutant from Bacillus subtilis | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, CHLORIDE ION, GLYCEROL, ... | | 著者 | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | 登録日 | 2013-07-22 | | 公開日 | 2014-04-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural insights into bacterial resistance to cerulenin.
Febs J., 281, 2014
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4OPF
 | | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 | | 分子名称: | NRPS/PKS | | 著者 | Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-02-05 | | 公開日 | 2014-02-19 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4OPE
 | | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS7 | | 分子名称: | NITRATE ION, NRPS/PKS | | 著者 | Osipiuk, J, Mack, J, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-02-05 | | 公開日 | 2014-02-19 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4OQJ
 | | Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmQ KS1 | | 分子名称: | GLYCEROL, PHOSPHATE ION, PKS, ... | | 著者 | Nocek, B, Mack, J, Endras, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2014-02-09 | | 公開日 | 2014-03-19 | | 最終更新日 | 2016-11-02 | | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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2WGE
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2C9H
 | | Structure of mitochondrial beta-ketoacyl synthase | | 分子名称: | MITOCHONDRIAL BETA-KETOACYL SYNTHASE, NICKEL (II) ION | | 著者 | Bunkoczi, G, Wu, X, Smee, C, Gileadi, O, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U. | | 登録日 | 2005-12-12 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of Mitochondrial Beta-Ketoacyl Synthase
To be Published
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2BUI
 | | E. COLI BETA-KETOACYL (ACYL CARRIER PROTEIN) SYNTHASE I IN COMPLEX WITH OCTANOIC ACID, 120K | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, OCTANOIC ACID (CAPRYLIC ACID) | | 著者 | Olsen, J.G, Von Wettstein-Knowles, P, Henriksen, A. | | 登録日 | 2005-06-13 | | 公開日 | 2005-06-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
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2BYZ
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2BYX
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2BZ3
 | | Structure of E.coli KAS I H298E mutant in complex with C12 fatty acid | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, LAURIC ACID, ... | | 著者 | Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A. | | 登録日 | 2005-08-10 | | 公開日 | 2006-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
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2VB9
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
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2WGF
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2VZ9
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2CF2
 | | Architecture of mammalian fatty acid synthase | | 分子名称: | FATTY ACID SYNTHASE, DH DOMAIN, ER DOMAIN, ... | | 著者 | Maier, T, Jenni, S, Ban, N. | | 登録日 | 2006-02-14 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | | 主引用文献 | Architecture of Mammalian Fatty Acid Synthase at 4.5 A Resolution.
Science, 311, 2006
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2VKZ
 | | Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex | | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, FATTY ACID SYNTHASE SUBUNIT ALPHA, ... | | 著者 | Johansson, P, Wiltschi, B, Kumari, P, Kessler, B, Vonrhein, C, Vonck, J, Oesterhelt, D, Grininger, M. | | 登録日 | 2008-01-07 | | 公開日 | 2008-08-12 | | 最終更新日 | 2017-06-21 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2VB7
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli, apo structure after soak in PEG solution | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
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2VBA
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound amino- thiazole inhibitor | | 分子名称: | 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1 | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
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2UV8
 | | Crystal structure of yeast fatty acid synthase with stalled acyl carrier protein at 3.1 angstrom resolution | | 分子名称: | FATTY ACID SYNTHASE SUBUNIT ALPHA (FAS2), FATTY ACID SYNTHASE SUBUNIT BETA (FAS1), FLAVIN MONONUCLEOTIDE | | 著者 | Leibundgut, M, Jenni, S, Frick, C, Ban, N. | | 登録日 | 2007-03-09 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase
Science, 316, 2007
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2VB8
 | | beta-ketoacyl-ACP synthase I (KAS) from E. coli with bound inhibitor thiolactomycin | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, CHLORIDE ION, THIOLACTOMYCIN | | 著者 | Pappenberger, G, Schulz-Gasch, T, Bailly, J, Hennig, M. | | 登録日 | 2007-09-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structure-Assisted Discovery of an Aminothiazole Derivative as a Lead Molecule for Inhibition of Bacterial Fatty-Acid Synthesis.
Acta Crystallogr.,Sect.D, 63, 2007
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2WGD
 | | Crystal structure of KasA of Mycobacterium tuberculosis | | 分子名称: | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Luckner, S.R, Kisker, C. | | 登録日 | 2009-04-17 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structures of Mycobacterium Tuberculosis Kasa Show Mode of Action within Cell Wall Biosynthesis and its Inhibition by Thiolactomycin
Structure, 17, 2009
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