PDB: 593 件ウェブページステータス検索Chemie searchBIRD

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2HDV	Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B 分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-20 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2HDX	Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide 分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform 著者 Hu, J, Hubbard, S.R. 登録日 2006-06-21 公開日 2006-08-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS. J.Mol.Biol., 361, 2006
2H46	Native domain-swapped dimer crystal structure of the Grb2 SH2 domain 分子名称: GLYCEROL, Growth Receptor Binding Protein 2 著者 Benfield, A.P, Martin, S.F, Whiddon, B.B. 登録日 2006-05-23 公開日 2006-06-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and energetic aspects of Grb2-SH2 domain-swapping. Arch.Biochem.Biophys., 462, 2007
2HMH	Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide. 分子名称: Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3 著者 Bergamin, E, Wu, J, Hubbard, S.R. 登録日 2006-07-11 公開日 2006-08-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3. Structure, 14, 2006
2HUW	X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand 分子名称: Growth factor receptor-bound protein 2, N-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-L-valyl-L-aspartamide, PHOSPHATE ION 著者 Benfield, A.P, Martin, S.F. 登録日 2006-07-27 公開日 2006-08-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 45, 2006
2IUH	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide 分子名称: C-KIT PHOSPHOTYROSYL PEPTIDE, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUG	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino-Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2IUI	Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with PDGFR phosphotyrosyl peptide 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, Platelet-derived growth factor receptor beta 著者 Nolte, R.T, Eck, M.J, Schlessinger, J, Shoelson, S.E, Harrison, S.C. 登録日 2006-06-03 公開日 2006-06-06 最終更新日 2021-04-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Pi 3-Kinase P85 Amino- Terminal Sh2 Domain and its Phosphopeptide Complexes Nat.Struct.Biol., 3, 1996
2JYQ	NMR structure of the apo v-Src SH2 domain 分子名称: Tyrosine-protein kinase transforming protein Src 著者 Taylor, J.D, Ababou, A, Williams, M.A, Ladbury, J.E. 登録日 2007-12-17 公開日 2008-06-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design Proteins, 73, 2008
2KK6	Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d 分子名称: Proto-oncogene tyrosine-protein kinase FER 著者 Tang, Y, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2009-06-15 公開日 2009-08-11 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d To be Published
2KNO	NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) 分子名称: Tensin-like C1 domain-containing phosphatase 著者 Chen, L, Feng, R, Liu, C, Zhu, G. 登録日 2009-08-27 公開日 2010-09-01 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of SH2 Domain of the Human Tensin Like C1 Domain Containing Phosphatase (TENC1) To be Published
2L3T	Solution structure of tandem SH2 domain from Spt6 分子名称: Transcription elongation factor SPT6 著者 Liu, J, Zhang, J, Wu, J, Shi, Y. 登録日 2010-09-22 公開日 2011-06-15 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the tandem SH2 domains from Spt6 and their binding to the phosphorylated RNA polymerase II C-terminal domain To be Published
2L4K	Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 分子名称: Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 著者 Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. 登録日 2010-10-07 公開日 2010-11-17 最終更新日 2012-10-03 実験手法 SOLUTION NMR 主引用文献 Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012
2L6K	Solution Structure of a Nonphosphorylated Peptide Recognizing Domain 分子名称: Tensin-like C1 domain-containing phosphatase 著者 Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X. 登録日 2010-11-22 公開日 2011-10-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1 Plos One, 6, 2011
2LNW	Identification and structural basis for a novel interaction between Vav2 and Arap3 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2LCT	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Gorenstein, N, Post, C. 登録日 2011-05-09 公開日 2011-06-01 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav. Mol.Cell.Biol., 31, 2011
2LNX	Solution structure of Vav2 SH2 domain 分子名称: Guanine nucleotide exchange factor VAV2 著者 Wu, B, Zhang, J, Wu, J, Shi, Y. 登録日 2012-01-05 公開日 2012-11-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
2MC1	Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide 分子名称: Proto-oncogene vav, Tyrosine-protein kinase SYK 著者 Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B. 登録日 2013-08-13 公開日 2013-08-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. Biopolymers, 99, 2013
2MK2	Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A 分子名称: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 著者 Yang, Y, Ramelot, T.A, Janjua, H, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2014-01-23 公開日 2014-03-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A. To be Published
2MQI	human Fyn SH2 free state 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, VanNuland, N. 登録日 2014-06-20 公開日 2015-07-29 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MRJ	Structure of Fyn protein SH2 bound 分子名称: Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, T, Van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2MRK	Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide 分子名称: C-terminal Tyrosine-protein kinase Fyn, Tyrosine-protein kinase Fyn 著者 Huculeci, R, Buts, L, Lenaerts, A.J, van Nuland, N. 登録日 2014-07-09 公開日 2015-07-15 最終更新日 2016-12-14 実験手法 SOLUTION NMR 主引用文献 Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
2AOA	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain 分子名称: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 著者 Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. 登録日 2005-08-12 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
2AUG	Crystal structure of the Grb14 SH2 domain 分子名称: Growth factor receptor-bound protein 14 著者 Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. 登録日 2005-08-27 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
2AOB	Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain 分子名称: 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 著者 Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. 登録日 2005-08-12 公開日 2005-10-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005

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