PDB: 278 件ウェブページステータス検索Chemie searchBIRD

---

4GNI	Structure of the Ssz1 ATPase bound to ATP and Magnesium 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein 著者 Bange, G, Sinning, I. 登録日 2012-08-17 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Structural characterization of a eukaryotic chaperone-the ribosome-associated complex. Nat.Struct.Mol.Biol., 20, 2013
4H5V	HSC70 NBD with Mg 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
7N1R	A novel and unique ATP hydrolysis to AMP by a human Hsp70 BiP 分子名称: ADENOSINE MONOPHOSPHATE, DI(HYDROXYETHYL)ETHER, Endoplasmic reticulum chaperone BiP, ... 著者 Yang, J, Musayev, F, Liu, Q. 登録日 2021-05-28 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A novel and unique ATP hydrolysis to AMP by a human Hsp70 Binding immunoglobin protein (BiP). Protein Sci., 31, 2022
4H5R	HSC70 NBD with Na, Cl and glycerol 分子名称: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4HY9	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin_LYZZ (residues 1 to 11) 分子名称: Chaperone protein DnaK, Pyrrhocoricin, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2012-11-13 公開日 2013-04-17 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
4HYB	Crystal structure of the substrate binding domain of E.coli DnaK in complex with pyrrhocoricin_LYZI (residues 1 to 10) 分子名称: Chaperone protein DnaK, Pyrrhocoricin, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2012-11-13 公開日 2013-04-17 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013
7O6R	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with 1H-Indazole 分子名称: 1H-indazole, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-04-12 公開日 2022-05-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODI	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with methanesulfonamide 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-04-29 公開日 2022-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODD	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with tricine 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-04-29 公開日 2022-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.984 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7ODB	Crystal structure of bovine Hsc70(aa1-554)E213A/D214A in complex with triazine-derivative 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6-methyl-5-sulfanylidene-2H-1,2,4-triazin-3-one, GLYCEROL, ... 著者 Zehe, M, Grimm, C, Sotriffer, C. 登録日 2021-04-29 公開日 2022-06-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.662 Å) 主引用文献 Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct. Acs Chem.Biol., 2024
7OOH	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 分子名称: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 To Be Published
7OOG	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 分子名称: 4-bromanylpyridin-2-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 To Be Published
7OOE	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226 分子名称: AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-05-27 公開日 2021-06-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.369 Å) 主引用文献 Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
7P31	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 分子名称: 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... 著者 Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. 登録日 2021-07-06 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with small molecule ligands To Be Published
4IO8	Crystal structure of human HSP70 complexed with 4-{(2R,3S,4R)-5-[(R)-6-Amino-8-(3,4-dichloro-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxymethyl}-benzonitrile 分子名称: 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Heat shock 70kDa protein 1A variant 著者 Musil, D, Scholz, S. 登録日 2013-01-07 公開日 2013-12-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Functional analysis of hsp70 inhibitors. Plos One, 8, 2013
4JWD	Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(15-28) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4JNE	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, Hsp70 CHAPERONE DnaK, ... 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-15 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4JNF	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: Hsp70 CHAPERONE DnaK 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-15 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.621 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4JWE	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(1-21) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4JN4	Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, GLYCEROL, ... 著者 Qi, R, Sarbeng, E.B, Liu, Q, Le, K.Q, Xu, X, Xu, H, Yang, J, Wong, J.L, Vorvis, C, Hendrickson, W.A, Zhou, L, Liu, Q. 登録日 2013-03-14 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nat.Struct.Mol.Biol., 20, 2013
4JWI	Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(35-43) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4J8F	Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip 分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, Hsc70-interacting protein, ... 著者 Li, Z, Bracher, A. 登録日 2013-02-14 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle. Nat.Struct.Mol.Biol., 20, 2013
4JWC	Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16) 分子名称: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2013-03-27 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7. Protein Pept.Lett., 21, 2014
4KBO	Crystal structure of the human Mortalin (GRP75) ATPase domain in the apo form 分子名称: SODIUM ION, Stress-70 protein, mitochondrial 著者 Amick, J, Page, R.C, Nix, J.C, Misra, S. 登録日 2013-04-23 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone. Protein Sci., 23, 2014
4EZP	Crystal structure of the substrate binding domain of E.coli DnaK in complex with A3-APO(residues 1 to 20) 分子名称: APO-monomer, Chaperone protein DnaK, SULFATE ION 著者 Zahn, M, Straeter, N. 登録日 2012-05-03 公開日 2013-04-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK. J.Mol.Biol., 425, 2013

<123456789101112>