PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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5JPJ	Crystal structure of 6aJL2-R24G 分子名称: 6aJL2 protein 著者 Pelaez-Aguilar, A.E, Diaz-Vilchis, A, Amero, C, Becerril, B, Rudino-Pinera, E. 登録日 2016-05-03 公開日 2017-06-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of 6aJL2-R24G light chain variable domain: Does crystal packing explain amyloid fibril formation? Biochem Biophys Rep, 20, 2019
8SBH	YeiE effector binding domain from E. coli 分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ... 著者 Momany, C, Nune, M, Brondani, J.C, Afful, D, Neidle, E. 登録日 2023-04-03 公開日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 FinR, a LysR-type transcriptional regulator involved in sulfur homeostasis with homologs in diverse microorganisms To Be Published
2YEX	Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors 分子名称: 5-METHYL-8-(1H-PYRROL-2-YL)[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE, GLYCEROL, SERINE/THREONINE-PROTEIN KINASE CHK1, ... 著者 Read, J.A, Breed, J, Haye, H, McCall, E, Vallentine, A, White, A. 登録日 2011-03-31 公開日 2012-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Synthesis and Evaluation of Triazolones as Checkpoint Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
5DQF	Horse Serum Albumin (ESA) in complex with Cetirizine 分子名称: (2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, CHLORIDE ION, ... 著者 Handing, K.B, Shabalin, I.G, Majorek, K.A, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2015-09-14 公開日 2015-12-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site. Mol.Immunol., 71, 2016
2YZ3	Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor 分子名称: (S)-2-(MERCAPTOMETHYL)-5-PHENYLPENTANOIC ACID, Metallo-beta-lactamase, SULFATE ION, ... 著者 Yamaguchi, Y, Yamagata, Y, Arakawa, Y, Kurosaki, H. 登録日 2007-05-02 公開日 2008-03-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor. J.Med.Chem., 50, 2007
2YER	Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors 分子名称: 1,2-ETHANEDIOL, 5-(HYDROXYMETHYL)-8-(1H-PYRROL-2-YL)-2H-[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1, ... 著者 Read, J.A, Breed, J, Haye, H, McCall, E, Vallentine, A, White, A, Otterbein, L. 登録日 2011-03-30 公開日 2012-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Synthesis and Evaluation of Triazolones as Checkpoint Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
6D71	Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1 著者 Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M. 登録日 2018-04-23 公開日 2019-10-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.7180779 Å) 主引用文献 Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase. J.Struct.Biol., 212, 2020
1W6B	Solution NMR Structure of a Long Neurotoxin from the Venom of the Asian Cobra, 20 Structures 分子名称: LONG NEUROTOXIN 1 著者 Talebzadeh-Farooji, M, Amininasab, M, Elmi, M.M, Naderi-Manesh, H, Sarbolouki, M.N. 登録日 2004-08-17 公開日 2004-12-22 最終更新日 2018-05-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy. Eur. J. Biochem., 271, 2004
2GAG	Heteroteterameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution 分子名称: 2-FUROIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Chen, Z.W, Hassan-Abdulah, A, Zhao, G, Jorns, M.S, Mathews, F.S. 登録日 2006-03-08 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 a resolution. J.Mol.Biol., 360, 2006
5K9H	Crystal structure of a glycoside hydrolase 29 family member from an unknown rumen bacterium 分子名称: 0940_GH29, GLYCEROL, SODIUM ION, ... 著者 Summers, E.L, Arcus, V.L. 登録日 2016-05-31 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.029 Å) 主引用文献 The structure of a glycoside hydrolase 29 family member from a rumen bacterium reveals unique, dual carbohydrate-binding domains. Acta Crystallogr.,Sect.F, 72, 2016
2FUK	Crystal structure of XC6422 from Xanthomonas campestris: a member of a/b serine hydrolase without lid at 1.6 resolution 分子名称: XC6422 protein 著者 Yang, C.Y, Chin, K.H, Chou, C.C, Wang, A.H.J, Chou, S.H. 登録日 2006-01-27 公開日 2006-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of XC6422 from Xanthomonas campestris at 1.6 A resolution: a small serine alpha/beta-hydrolase Acta Crystallogr.,Sect.F, 62, 2006
6KCK	Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with pterin and p-hydroxybenzoate 分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, CALCIUM ION, ... 著者 Chitnumsub, P, Jaruwat, A, Yuthavong, Y. 登録日 2019-06-28 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
6JWQ	Crystal structure of Plasmodium falciparum HPPK-DHPS wild type 分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... 著者 Chitnumsub, P, Jaruwat, A, Yuthavong, Y. 登録日 2019-04-21 公開日 2020-02-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
6JWU	Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with STZ-DHP 分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ... 著者 Chitnumsub, P, Jaruwat, A, Yuthavong, Y. 登録日 2019-04-21 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
6KCM	Crystal structure of Plasmodium falciparum HPPK-DHPS S436F/A437G/A613S with pterin and p-hydrobenzoate 分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Chitnumsub, P, Jaruwat, A, Yuthavong, Y. 登録日 2019-06-28 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
6JWS	Crystal structure of Plasmodium falciparum HPPK-DHPS A437G with Pteroate 分子名称: 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Chitnumsub, P, Jaruwat, A, Yuthavong, Y. 登録日 2019-04-21 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
6KFZ	SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec at 1.96 angstrom resolution 分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE 著者 Nakamura, R, Takahashi, Y, Fujishiro, T. 登録日 2019-07-09 公開日 2019-10-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes. Febs J., 287, 2020
6KUB	Crystal structure of Plasmodium falciparum histo-aspartic protease (HAP) zymogen (Form 1) 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, HAP protein 著者 Rathore, I, Mishra, V, Bhaumik, P. 登録日 2019-08-31 公開日 2020-05-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Activation mechanism of plasmepsins, pepsin-like aspartic proteases from Plasmodium, follows a unique trans-activation pathway. Febs J., 288, 2021
6L0I	Crystal structure of dihydroorotase in complex with malate at pH6.5 from Saccharomyces cerevisiae 分子名称: (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION 著者 Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. 登録日 2019-09-26 公開日 2020-12-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
6L0F	Crystal structure of dihydroorotase in complex with 5-Aminouracil from Saccharomyces cerevisiae 分子名称: 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, Dihydroorotase, ZINC ION 著者 Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. 登録日 2019-09-26 公開日 2020-12-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 Structural basis for the interaction modes of dihydroorotase with the anticancer drugs 5-fluorouracil and 5-aminouracil. Biochem.Biophys.Res.Commun., 551, 2021
4FOL	S-formylglutathione hydrolase Variant H160I 分子名称: S-formylglutathione hydrolase 著者 Legler, P.M, Millard, C.B. 登録日 2012-06-20 公開日 2012-09-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: Evidence for an oxidation sensitive motif. Arch.Biochem.Biophys., 528, 2012
5DLP	Acetylcholinesterase Methylene Blue no PEG 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, Acetylcholinesterase, ... 著者 Dym, O. 登録日 2015-09-07 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex. Protein Sci., 25, 2016
6KLK	Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU 分子名称: 5-FLUOROURACIL, D-hydantoinase/dihydropyrimidinase, ZINC ION 著者 Huang, Y.H, Chen, I.C, Huang, C.Y. 登録日 2019-07-30 公開日 2019-11-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.759 Å) 主引用文献 Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil. Biochem.Biophys.Res.Commun., 519, 2019
6LJJ	Swine dUTPase in complex with alpha,beta-iminodUTP and magnesium ion 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, ... 著者 Liang, R, Peng, G.Q. 登録日 2019-12-16 公開日 2020-11-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development. J.Biol.Chem., 296, 2020
4FGW	Structure of Glycerol-3-Phosphate Dehydrogenase, GPD1, from Sacharomyces Cerevisiae 分子名称: Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 著者 Aparicio, D, Munmun, N, Carpena, X, Fita, I, Loewen, P. 登録日 2012-06-05 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure of glycerol-3-phosphate dehydrogenase (GPD1) from Saccharomyces cerevisiae at 2.45A resolution Acta Crystallogr.,Sect.F, 68, 2012

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