2BXU
 
 | | Design and Discovery of Novel, Potent Thrombin Inhibitors with a Solubilizing Cationic P1-P2-Linker | | 分子名称: | 1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL, ALPHA THROMBIN, HIRUDIN | | 著者 | Bulat, S, Bosio, S, Grabowski, E, Papadopoulos, M.A, Cerezo-Galvez, S, Rosenbaum, C, Matassa, V.G, Ott, I, Metz, G, Schamberger, J, Sekul, R, Feurer, A. | | 登録日 | 2005-07-27 | | 公開日 | 2006-10-26 | | 最終更新日 | 2016-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker
Lett.Drug Des.Discovery, 3, 2006
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2BLZ
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2BLH
 | | Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Nienhaus, K, Ostermann, A, Nienhaus, G.U, Parak, F.G, Schmidt, M. | | 登録日 | 2005-03-04 | | 公開日 | 2005-04-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W
Biochemistry, 44, 2005
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2BYL
 | | Structure of ornithine aminotransferase triple mutant Y85I Y55A G320F | | 分子名称: | ORNITHINE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Markova, M, Peneff, C, Hewlins, M.J.E, Schirmer, T, John, R.A. | | 登録日 | 2005-08-03 | | 公開日 | 2005-09-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Determinants of Substrate Specificity in Omega-Aminotransferases.
J.Biol.Chem., 280, 2005
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2CII
 | | The crystal structure of H-2Db complexed with a partial peptide epitope suggests an MHC Class I assembly-intermediate | | 分子名称: | BETA-2-MICROGLOBULIN, GLYCEROL, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, ... | | 著者 | Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E.Y, Elliott, T. | | 登録日 | 2006-03-21 | | 公開日 | 2006-03-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate.
J. Biol. Chem., 281, 2006
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2C9S
 | | 1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase | | 分子名称: | ACETATE ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S. | | 登録日 | 2005-12-14 | | 公開日 | 2005-12-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
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2C7C
 | | FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180) | | 分子名称: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | | 著者 | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | | 登録日 | 2005-11-22 | | 公開日 | 2006-01-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
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2E6W
 | | Solution structure and calcium binding properties of EF-hands 3 and 4 of calsenilin | | 分子名称: | CALCIUM ION, Calsenilin | | 著者 | Yu, L, Sun, C, Mendoza, R, Hebert, E, Pereda-Lopez, A, Hajduk, P.J, Olejniczak, E.T. | | 登録日 | 2007-01-05 | | 公開日 | 2007-11-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and calcium-binding properties of EF-hands 3 and 4 of calsenilin.
Protein Sci., 16, 2007
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2E85
 | | Crystal Structure of the Hydrogenase 3 Maturation protease | | 分子名称: | CALCIUM ION, Hydrogenase 3 maturation protease | | 著者 | Tanaka, T, Kumarevel, T.S, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-01-18 | | 公開日 | 2008-01-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of hydrogenase maturating endopeptidase HycI from Escherichia coli
Biochem.Biophys.Res.Commun., 389, 2009
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2AMN
 | | Solution structure of Fowlicidin-1, a novel Cathelicidin antimicrobial peptide from chicken | | 分子名称: | cathelicidin | | 著者 | Xiao, Y, Dai, H, Bommineni, Y.R, Prakash, O, Zhang, G. | | 登録日 | 2005-08-09 | | 公開日 | 2006-07-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken.
Febs J., 273, 2006
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2BH4
 | | X-ray structure of the M100K variant of ferric cyt c-550 from Paracoccus versutus determined at 100 K. | | 分子名称: | CYTOCHROME C-550, HEME C | | 著者 | Worrall, J.A.R, Van Roon, A.-M.M, Ubbink, M, Canters, G.W. | | 登録日 | 2005-01-07 | | 公開日 | 2005-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The Effect of Replacing the Axial Methionine Ligand with a Lysine Residue in Cytochrome C-550 from Paracoccus Versutus Assessed by X-Ray Crystallography and Unfolding.
FEBS J., 272, 2005
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2BF6
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2BLY
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2BNK
 | | The structure of phage phi29 replication organizer protein p16.7 | | 分子名称: | EARLY PROTEIN GP16.7 | | 著者 | Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J. | | 登録日 | 2005-03-28 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding.
J.Biol.Chem., 280, 2005
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2BH5
 | | X-ray structure of the M100K variant of ferric cyt c-550 from Paracoccus versutus determined at 295 K. | | 分子名称: | CYTOCHROME C-550, HEME C | | 著者 | Worrall, J.A.R, van Roon, A.-M.M, Ubbink, M, Canters, G.W. | | 登録日 | 2005-01-07 | | 公開日 | 2005-05-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The Effect of Replacing the Axial Methionine Ligand with a Lysine Residue in Cytochrome C-550 from Paracoccus Versutus Assessed by X-Ray Crystallography and Unfolding.
FEBS J., 272, 2005
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2BF8
 | | Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K | | 分子名称: | UBIQUITIN-CONJUGATING ENZYME E2-25 KDA, UBIQUITIN-LIKE PROTEIN SMT3C | | 著者 | Pichler, A, Knipscheer, P, Oberhofer, E, Van Dijk, W.J, Korner, R, Velgaard Olsen, J, Jentsch, S, Melchior, F, Sixma, T.K. | | 登録日 | 2004-12-06 | | 公開日 | 2005-02-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Sumo Imodification of the Ubiquitin Conjugating Enzyme E2-25K
Nat.Struct.Mol.Biol., 12, 2005
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2AM1
 | | sp protein ligand 1 | | 分子名称: | 2,4-DICHLORO-N-(3-CYANO-4,5,6,7-TETRAHYDRO-BENZOTHIOPHEN-2YL)-5-(MORPHOLINE-4-SULFONYL)-BENZAMIDE, GLYCEROL, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, ... | | 著者 | Longenecker, K.L, Stamper, G.F, Hajduk, P.J, Fry, E.H, Jakob, C.G, Harlan, J.E, Edalji, R, Bartley, D.M, Walter, K.A, Solomon, L.R. | | 登録日 | 2005-08-08 | | 公開日 | 2006-01-24 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
Protein Sci., 14, 2005
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2AGH
 | | Structural basis for cooperative transcription factor binding to the CBP coactivator | | 分子名称: | Crebbp protein, Myb proto-oncogene protein, Zinc finger protein HRX | | 著者 | De Guzman, R.N, Goto, N.K, Dyson, H.J, Wright, P.E. | | 登録日 | 2005-07-26 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Cooperative Transcription Factor Binding to the CBP Coactivator
J.Mol.Biol., 355, 2006
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2AM2
 | | sp protein ligand 2 | | 分子名称: | 2-CHLORO-N-(3-CYANO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHEN-2-YL)-5-DIETHYLSULFAMOYL-BENZAMIDE, UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase, MurF protein | | 著者 | Longenecker, K.L, Stamper, G.F, Hajduk, P.J, Fry, E.H, Jakob, C.G, Harlan, J.E, Edalji, R, Bartley, D.M, Walter, K.A, Solomon, L.R. | | 登録日 | 2005-08-08 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure
Protein Sci., 14, 2005
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2E5C
 | | Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate | | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase | | 著者 | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | | 登録日 | 2006-12-20 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase
J.Biochem., 147, 2010
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2E3H
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2E0P
 | | The crystal structure of Cel44A | | 分子名称: | CALCIUM ION, CHLORIDE ION, Endoglucanase, ... | | 著者 | Kitago, Y, Karita, S, Watanabe, N, Sakka, K, Tanaka, I. | | 登録日 | 2006-10-11 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Cel44A, a glycoside hydrolase family 44 endoglucanase from Clostridium thermocellum.
J.Biol.Chem., 282, 2007
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2EO7
 | | Crystal structure of Cel44A, GH family 44 endoglucanase from Clostridium thermocellum | | 分子名称: | CALCIUM ION, CHLORIDE ION, Endoglucanase, ... | | 著者 | Kitao, Y, Karita, S, Watanabe, N, Sakka, K, Tanaka, I. | | 登録日 | 2007-03-29 | | 公開日 | 2007-09-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of Cel44A, a glycoside hydrolase family 44 endoglucanase from Clostridium thermocellum.
J.Biol.Chem., 282, 2007
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5H6V
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2B4J
 | | Structural basis for the recognition between HIV-1 integrase and LEDGF/p75 | | 分子名称: | GLYCEROL, Integrase (IN), PC4 and SFRS1 interacting protein, ... | | 著者 | Cherepanov, P, Ambrosio, A.L, Rahman, S, Ellenberger, T, Engelman, A. | | 登録日 | 2005-09-24 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
Proc.Natl.Acad.Sci.Usa, 102, 2005
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