7X3J
 
 | | Cryo-EM structure of human TRiC-tubulin-S2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | | 著者 | Cong, Y, Liu, C.X. | | 登録日 | 2022-03-01 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
|
|
7X6Q
 | | cryo-EM structure of human TRiC-ATP-closed state | | 分子名称: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | | 著者 | Cong, Y, Liu, C.X. | | 登録日 | 2022-03-08 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
|
|
7X7Y
 | | Cryo-EM structure of Human TRiC-ATP-open state | | 分子名称: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | | 著者 | Cong, Y, Liu, C.X. | | 登録日 | 2022-03-10 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
|
|
6H4B
 | | A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature. | | 分子名称: | ORF026, Orf20 | | 著者 | Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A. | | 登録日 | 2018-07-20 | | 公開日 | 2019-08-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | | 主引用文献 | The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
|
|
8E1I
 | | Asp1 kinase in complex with ATP Mg 5-IP7 | | 分子名称: | (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, ADENOSINE-5'-TRIPHOSPHATE, Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase, ... | | 著者 | Goldgur, Y, Shuman, S, Benjamin, B. | | 登録日 | 2022-08-10 | | 公開日 | 2022-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.
Mbio, 13, 2022
|
|
5M8W
 | | PCE reductive dehalogenase from S. multivorans in complex with 4-chlorophenol | | 分子名称: | 4-chlorophenol, BENZAMIDINE, GLYCEROL, ... | | 著者 | Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. | | 登録日 | 2016-10-30 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.279 Å) | | 主引用文献 | Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer.
Nat Commun, 8, 2017
|
|
2K2I
 | | NMR Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a repeat sequence of human Sfi1 (R641-T660) | | 分子名称: | Centrin-2, SFI1 peptide | | 著者 | Martinez-Sanz, J, Assairi, L, Blouquit, Y, Duchambon, P, Mouawad, L, Craescu, C. | | 登録日 | 2008-04-02 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics and thermodynamics of the human centrin 2/hSfi1 complex
J.Mol.Biol., 395, 2010
|
|
7YFY
 | | Cryo-EM structure of the Mili-piRNA- target ternary complex | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, RNA (5'-R(P*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-09 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
|
|
7YAS
 | | HYDROXYNITRILE LYASE, LOW TEMPERATURE NATIVE STRUCTURE | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, PROTEIN (HYDROXYNITRILE LYASE), ... | | 著者 | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | | 登録日 | 1999-03-15 | | 公開日 | 1999-10-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis.
Protein Sci., 8, 1999
|
|
6TX2
 | | Human HPF1 | | 分子名称: | Histone PARylation factor 1, SODIUM ION | | 著者 | Suskiewicz, M.J, Ahel, I. | | 登録日 | 2020-01-13 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
|
|
6EB3
 | | Structural and enzymatic characterization of an esterase from a metagenomic library | | 分子名称: | 1,2-ETHANEDIOL, 1,3-dihydroxypropan-2-yl butanoate, 2-hydroxypropane-1,3-diyl dibutanoate, ... | | 著者 | Guzzo, C.R, Carvalho, C.F, Teixeira, R.D, Farah, C.S. | | 登録日 | 2018-08-03 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Functional and Structural characterisation of an Esterase from Amazonian Dark Soil
To Be Published
|
|
8DQI
 | | Crystal structure of pyrrolysyl-tRNA synthetase from Methanomethylophilus alvus engineered for acridone amino acid (RS1) bound to ATP and acridone after 2- weeks of crystal growth | | 分子名称: | (2~{S})-2-azanyl-3-(9-oxidanylidene-10~{H}-acridin-2-yl)propanoic acid, AA_TRNA_LIGASE_II domain-containing protein, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gottfried-Lee, I, Karplus, P.A, Mehl, R.A, Cooley, R.B. | | 登録日 | 2022-07-19 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structures of Methanomethylophilus alvus Pyrrolysine tRNA-Synthetases Support the Need for De Novo Selections When Altering the Substrate Specificity.
Acs Chem.Biol., 17, 2022
|
|
6HXE
 | |
6I0R
 | | Structure of quinolinate synthase in complex with 5-mercaptopyridine-2,3-dicarboxylic acid | | 分子名称: | 5-mercaptopyridine-2,3-dicarboxylic acid, FE (III) ION, HYDROSULFURIC ACID, ... | | 著者 | Volbeda, A, Fontecilla-Camps, J.C. | | 登録日 | 2018-10-26 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination.
Chem.Commun.(Camb.), 55, 2019
|
|
2IKH
 | | Human aldose reductase complexed with nitrofuryl-oxadiazol inhibitor at 1.55 A | | 分子名称: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {[5-(5-NITRO-2-FURYL)-1,3,4-OXADIAZOL-2-YL]THIO}ACETIC ACID | | 著者 | Steuber, H, Koch, C, Heine, A, Klebe, G. | | 登録日 | 2006-10-02 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution
J.Mol.Biol., 368, 2007
|
|
2IKJ
 | | Human aldose reductase complexed with nitro-substituted IDD-type inhibitor | | 分子名称: | (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Steuber, H, Koch, C, Heine, A, Klebe, G. | | 登録日 | 2006-10-02 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural and Thermodynamic Study on Aldose Reductase: Nitro-substituted Inhibitors with Strong Enthalpic Binding Contribution
J.Mol.Biol., 368, 2007
|
|
1FWO
 | | THE SOLUTION STRUCTURE OF A 35-RESIDUE FRAGMENT FROM THE GRANULIN/EPITHELIN-LIKE SUBDOMAIN OF RICE ORYZAIN BETA (ROB 382-416 (C398S,C399S,C407S,C413S)) | | 分子名称: | ORYZAIN BETA CHAIN | | 著者 | Tolkatchev, D, Xu, P, Ni, F. | | 登録日 | 2000-09-24 | | 公開日 | 2001-05-09 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A peptide derived from the C-terminal part of a plant cysteine protease folds into a stack of two beta-hairpins, a scaffold present in the emerging family of granulin-like growth factors.
J.Pept.Res., 57, 2001
|
|
5MRV
 | | Crystal structure of human carboxypeptidase O in complex with NvCI | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase O, Metallocarboxypeptidase inhibitor, ... | | 著者 | Garcia-Pardo, J, Garcia-Guerrero, M.C, Fernandez-Alvarez, R, Lyons, P, Aviles, F.X, Lorenzo, J, Reverter, D. | | 登録日 | 2016-12-27 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | | 主引用文献 | Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
8SF6
 | | Promiscuous amino acid gamma synthase from Caldicellulosiruptor hydrothermalis in closed conformation | | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | 著者 | Buller, A.R, Zmich, A.P, Bingman, C.A. | | 登録日 | 2023-04-10 | | 公開日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family.
Acs Catalysis, 13, 2023
|
|
2E0H
 | |
8SF5
 | |
1Q9S
 | | Crystal structure of riboflavin kinase with ternary product complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | | 著者 | Karthikeyan, S, Zhou, Q, Osterman, A.L, Zhang, H. | | 登録日 | 2003-08-25 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Ligand binding-induced conformational changes in riboflavin kinase: structural basis for the ordered mechanism.
Biochemistry, 42, 2003
|
|
5JZQ
 | |
1GPR
 | |
5N04
 | | X-ray crystal structure of an LPMO | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... | | 著者 | Frandsen, K.E.H, Poulsen, J.-C.N, Lo Leggio, L. | | 登録日 | 2017-02-02 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH.
Carbohydr. Res., 448, 2017
|
|
